Protein Alignment CG15111 and ACOT2

DIOPT Version :10

• Sequence 1: NP_725856.1
• Gene: CG15111 / 37200
• FlyBaseID: FBgn0034419
• Length: 411
• Species: Drosophila melanogaster
• Sequence 2: NP_006812.3
• Gene: ACOT2 / 10965
• HGNCID: 18431
• Length: 483
• Species: Homo sapiens
• Alignment Length: 314
• Identity: 74/314 - (23%)
• Similarity: 107/314 - (34%)
• Gaps: 97/314 - (30%)

  Fly    50 PLIFRYSVTFQRGILFLTFIKYPKG----LDLTKPESVGLYATRNFYITVKDHDQDEDGVRVG-- 108
            |:..|.|:..::|.||....:|...    |||.:..::|                   |...|
Human    93 PVTLRASLRDEKGALFQAHARYRADTLGELDLERAPALG-------------------GSFAGLE 138

  Fly   109 ----VWHVLPSN-AVRRFKRELR----VEEEV--AQDPDQQLDPAPG-----NERELKELSPAIR 157
                :|.:.|.. .||..||::|    ||.||  ..|||      ||     ...|...|.|.:|
Human   139 PMGLLWALEPEKPLVRLVKRDVRTPLAVELEVLDGHDPD------PGRLLCQTRHERYFLPPGVR 197

  Fly   158 SEFPV---------VLPENEQLFYERLLRMPGGTVVLYLHGNTASRGSGHRSEVYKLLRKLNYHV 213
            .| ||         .||.....|       ||   ::.:.|.    |.|.......||....:.|
Human   198 RE-PVRVGRVRGTLFLPPEPGPF-------PG---IVDMFGT----GGGLLEYRASLLAGKGFAV 247

  Fly   214 FSFDYRGYADSDPVPPTEEGVVRDAMMVFEYIANTTSNPIVVWGHSLG-TGVAT--HLCAKLASL 275
            .:..|..|.|   :|.|.|.:   .:..||...|...:...|.|..:| .|::.  .||..:||.
Human   248 MALAYYNYED---LPKTMETL---HLEYFEEAMNYLLSHPEVKGPGVGLLGISKGGELCLSMASF 306

  Fly   276 RERAPRGVILESPFTNIRDEIRMHPFAKLYK--NLPWFNFTISQPMYTNRLRFE 327
            .:.....|::.....|:...:.       ||  .||        |:..||.|.:
Human   307 LKGITAAVVINGSVANVGGTLH-------YKGETLP--------PVGVNRNRIK 345

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15111	NP_725856.1	FrsA	183..381	CDD:440691	33/150 (22%)
ACOT2	NP_006812.3	Bile_Hydr_Trans	78..202	CDD:461422	35/134 (26%)
		alpha/beta hydrolases	207..>319	CDD:473884	29/131 (22%)
		BAAT_C	265..474	CDD:430252	21/99 (21%)
		Microbody targeting signal. /evidence=ECO:0000255	481..483