DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15118 and AT1G62050

DIOPT Version :9

Sequence 1:	NP_611396.1	Gene:	CG15118 / 37199	FlyBaseID:	FBgn0034418	Length:	637	Species:	Drosophila melanogaster
Sequence 2:	NP_564790.3	Gene:	AT1G62050 / 842501	AraportID:	AT1G62050	Length:	624	Species:	Arabidopsis thaliana

Alignment Length:	530	Identity:	136/530 - (25%)
Similarity:	229/530 - (43%)	Gaps:	120/530 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 EQLQAAIDQNDKEKIDPRGRTPLMLAVRLANLPCVKCLLAAKCNATYE-YEGWSIVQEAVCTGDV 86
            :|:.|.:|:.|.    |...|||.|||||.:|...:.:.:|..:.:.: ..||:.:|||.|..:.
plant    65 DQISAVLDRRDV----PSRETPLHLAVRLDDLFAARAISSAGGDISLQNASGWNPLQEAFCRRNS 125

  Fly    87 DILTAIIEVRDLQRHVQRVT------HVPKLLQHLLDAPDFYIEMKWEF-TSWVPLMSRLCPSDT 144
            :::..::      ||..|:.      .:|:|:..|....|||:|:.:.| :|.:|.:.::.||||
plant   126 EVMKVLL------RHHHRLAWCKWRRRLPRLIAVLRRMRDFYMEISFHFESSVIPFVGKIAPSDT 184

  Fly   145 YKVYKRGANVRIDTTLLGFDNNTWQRGNRSYIFKGAKETA------TMIEIDHDTNEVM--VEEM 201
            ||::||..|:|.||||.|||....||.::|::|.|..:.:      :::.::.|..:::  .|..
plant   185 YKIWKRDGNLRADTTLAGFDGLKIQRADQSFLFLGDGDESLDISPGSLLVLNRDDRKILDAFESA 249

  Fly   202 SSDIGDI-VA--------IPPALGTVRARLNAPVITNNIEMDKISFERNKCGIWGW-RSEKSEMI 256
            .:.|.|. :|        ..|.:...:|.|                    .|...| |.||.|.:
plant   250 GAPISDSDIAGFCSQSSLYRPGMDVTKAEL--------------------VGRTNWRRQEKMENV 294

  Fly   257 NGYNCKVYGASNVEFVTKTR--MDHLSEEQIKNKTARTPLHSLLGIADEDYV---SPADAAAALK 316
            ..:..:||....|.|..::|  :.....||:      .||.  |...||.::   :|:..|
plant   295 GEWKARVYEIQKVTFSFRSRKIVTGDGSEQV------LPLE--LDEDDEGFLVAENPSFLA---- 347

  Fly   317 DRTPSPRLEEASNAGVENG------GRNS--------PAPGNQSNGSSAGASGTSTPKSS---VT 364
               |.||.:...::.|:..      ||.|        |.|..||.......|....|:.|   |.
plant   348 ---PPPRSQRRHSSFVKEDRDWISVGRKSVDVYPSAAPPPPRQSQSPRRSVSQFQPPRRSMAQVQ 409

  Fly   365 PEEYFTQEFDLHGRDVGGPKNLSTK-------------VQRFRANLWLAEEHPIRLQEQVLPILD 416
            |......:.....|.|..|..:|..             |:....::||.|:.|:: .|::||:||
plant   410 PPRRSVAQAQPPRRSVALPSTVSPVNPPPSPQIKEKEFVKSLHPSVWLTEQFPLK-TEELLPLLD 473

  Fly   417 LMSTMASPHVSKLRDFITMQLPAG-FPVKVEIPLFHVLNACITFGNVFALT------TPVD---- 470
            :::..... |:::||.:|.:.|.| ||||:.||:...:...|||.....|.      ||:.
plant   474 ILANKVKA-VARMRDLLTTKFPPGTFPVKLSIPVVPTVKVVITFTKFVELPPAETFYTPLSSPRF 537

  Fly   471 -HVATLQEQD 479
             :.||..|:|
plant   538 LYSATAGEED 547

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15118	NP_611396.1	ANK	10..>94	CDD:238125	21/71 (30%)
		ANK repeat	12..38	CDD:293786	4/14 (29%)
		Ank_2	13..94	CDD:289560	21/71 (30%)
		ANK repeat	40..70	CDD:293786	10/29 (34%)
		GPCR_chapero_1	155..497	CDD:288735	93/390 (24%)
		vWFA	<558..627	CDD:294047
AT1G62050	NP_564790.3	ANK	17..>135	CDD:238125	22/79 (28%)
		ANK repeat	18..75	CDD:293786	3/9 (33%)
		ANK repeat	80..109	CDD:293786	10/28 (36%)
		Ank_4	81..132	CDD:290365	16/50 (32%)
		GPCR_chapero_1	195..597	CDD:288735	93/390 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D425969at2759
OrthoFinder	1	1.000	-	-		FOG0000585
OrthoInspector	1	1.000	-	-		mtm1007
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12447
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X742
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.020