DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15118 and AT3G24210

DIOPT Version :9

Sequence 1:	NP_611396.1	Gene:	CG15118 / 37199	FlyBaseID:	FBgn0034418	Length:	637	Species:	Drosophila melanogaster
Sequence 2:	NP_189063.2	Gene:	AT3G24210 / 822007	AraportID:	AT3G24210	Length:	607	Species:	Arabidopsis thaliana

Alignment Length:	518	Identity:	145/518 - (27%)
Similarity:	222/518 - (42%)	Gaps:	112/518 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 EQLQAAIDQNDKEKIDPRGRTPLMLAVRLANLPCVKCLLAAKCNATYEYE-GWSIVQEAVCTGDV 86
            :.:.|.||:.|.    |...|||.|||:|.:...|:.|:.|..:.|.:.| ||:.:|||||:...
plant    56 DTISAVIDRRDV----PSRDTPLHLAVKLCDSTSVEMLMVAGADWTLQNEDGWNALQEAVCSRQE 116

  Fly    87 DILTAIIEVRDLQRHVQRVT------HVPKLLQHLLDAPDFYIEMKWEF-TSWVPLMSRLCPSDT 144
            .|...|:      ||.|.:.      .:|:|:..:....|||:||.:.| :|.||.:|::.||||
plant   117 AIAMIIV------RHYQPLAWAKWCRRLPRLIATMSKMKDFYLEMSFHFESSVVPFVSKVAPSDT 175

  Fly   145 YKVYKRGANVRIDTTLLGFDNNTWQRGNRSYIF------KGAKETATMIEIDHDTNEVMVEEMSS 203
            |||:|.|:|:|.|.|:.|||....||.::|.:|      .|.....::..::|...||| ..:..
plant   176 YKVWKVGSNLRADMTMAGFDGFKIQRSDQSILFLGDGSEDGEVARGSLYMVNHKDKEVM-NALDG 239

  Fly   204 DIGDIVAIPPALGTVRARLNAPVITN------NIEMDKISFERNKCGIWGW-RSEKSEMINGYNC 261
            ..|     .|:...||..:.|...:|      ::....:|.:.|      | |.|||||:..:..
plant   240 ACG-----VPSEEEVRKEVAAMCKSNIFRPGIDVTQAVLSPQTN------WRRQEKSEMVGPWKA 293

  Fly   262 KVYGASNVEFVTKTR---------------MDHLSEEQIKNKTARTPL-----------HSLLGI 300
            |||..:||....|:|               .|.|::|:.|.......|           :..:..
plant   294 KVYEMNNVVVSVKSRKVPGSLAVEGGDDDICDVLTDEEQKQLEDALKLDLPDFPNVNGENGFIVH 358

  Fly   301 ADEDYVSPADAAAALKD----------------RTPSPRLEEASNAGVEN--GGRNSPAPGNQSN 347
            ..||:|. |:..|..|.                :...||.....|..|.|  |..|...||..
plant   359 HQEDHVE-ANKKAEKKGWLGGWRKKETKQEKQIQYAPPRSSLCVNEKVSNLLGESNQIKPGRH-- 420

  Fly   348 GSSAGASGTSTPKSSVTPEEYFTQEFDLHGRDVGGPKNLSTKVQRFRANLWLAEEHPIRLQEQVL 412
              |........||:.|:.:.....|:         .|.|       |..|||:...|:: .|::|
plant   421 --SVDNEHYRKPKALVSDKTRHESEY---------KKGL-------RPVLWLSPNFPLQ-TEELL 466

  Fly   413 PILDLMSTMASPHVSKLRDFITMQLPAG-FPVKVEIPLFHVLNACITFGNVFALTTPVDHVAT 474
            |:||:::..... :.:||:.:|.:||:| |||||.||:...:...:|| ..|....|||...|
plant   467 PLLDILANKVKA-IRRLRELLTTKLPSGTFPVKVAIPVVPTIKVLVTF-TKFEEIEPVDEFKT 527

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15118	NP_611396.1	ANK	10..>94	CDD:238125	26/71 (37%)
		ANK repeat	12..38	CDD:293786	4/14 (29%)
		Ank_2	13..94	CDD:289560	26/71 (37%)
		ANK repeat	40..70	CDD:293786	11/29 (38%)
		GPCR_chapero_1	155..497	CDD:288735	94/378 (25%)
		vWFA	<558..627	CDD:294047
AT3G24210	NP_189063.2	Ank_5	59..110	CDD:290568	20/54 (37%)
		ANK	<60..>125	CDD:238125	26/74 (35%)
		ANK repeat	71..100	CDD:293786	11/28 (39%)
		GPCR_chapero_1	186..585	CDD:288735	94/378 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D425969at2759
OrthoFinder	1	1.000	-	-		FOG0000585
OrthoInspector	1	1.000	-	-		mtm1007
orthoMCL	1	0.900	-	-		OOG6_102396
Panther	1	1.100	-	-	O	PTHR12447
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X742
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.920