DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15118 and Ankrd13c

DIOPT Version :9

Sequence 1:	NP_611396.1	Gene:	CG15118 / 37199	FlyBaseID:	FBgn0034418	Length:	637	Species:	Drosophila melanogaster
Sequence 2:	NP_001178499.2	Gene:	Ankrd13c / 685374	RGDID:	1595074	Length:	540	Species:	Rattus norvegicus

Alignment Length:	492	Identity:	146/492 - (29%)
Similarity:	242/492 - (49%)	Gaps:	105/492 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 YPLHWHIWHNELEQLQAAIDQNDKEKIDPRGRTPLMLAVRLANLPCVKCLLAAKCNATYEY---E 72
            ||:|..::..::.:|.:.|..::..:.|..|.|||.|||.|.|..|...|||.  ||..:.   :
  Rat   113 YPVHECVFKGDVRRLSSLIRTHNIGQKDNHGNTPLHLAVMLGNKECAHLLLAH--NAPVKVKNAQ 175

  Fly    73 GWSIVQEAVCTGDVDILTAIIEVRDLQRHVQRVTHVPKLLQHLLDAPDFYIEMKWEFTSWVPLMS 137
            |||.:.||:..||..::||::.....|.........|:||:.|.:..|||:|:.|:|.|||||:|
  Rat   176 GWSPLAEAISYGDRQMITALLRKLKQQSRESVGEKRPRLLKALKELGDFYLELHWDFQSWVPLLS 240

  Fly   138 RLCPSDTYKVYKRGANVRIDTTLLGFDNNTWQRGNRSYIFKG-AKETATMIEID----------H 191
            |:.|||..|:||:|.|:|:||||:.|.:...|||:.|:||.| |..:.:.:.:|          |
  Rat   241 RILPSDACKIYKQGINIRLDTTLIDFTDMKCQRGDLSFIFSGDAAPSESFVVLDNEQKVYQRIHH 305

  Fly   192 DTNEVMVEE-----MSSDIGDIVAIPPALGTVRARLNAPVITNNIEMDKISFERNKCGIWGWRSE 251
            :.:|:..||     |||||                .:|.:.|.:     |||.|.:.| |.:|.:
  Rat   306 EESEMETEEEVDILMSSDI----------------YSATLSTKS-----ISFTRAQTG-WLFRED 348

  Fly   252 KSEMINGYNCKVYGASNVEFVTKTRMDHLSEEQI-KNKTARTPLHSLLGIADEDYVSPADAAAAL 315
            |:|.:..:....|..:.:...::.|.:|||||.| :||.....|.....:.::::
  Rat   349 KTERVGNFLADFYLVNGLVLESRKRREHLSEEDILRNKAIMESLSKGGSLTEQNF---------- 403

  Fly   316 KDRTPSPRLEEASNAGVENGGRNSPAPGNQSNGSSAGASGTSTPKSSVTPEEYFTQEFDLHGRDV 380
                             |...|.|..|               .|::::|.|||.:.|   :|:..
  Rat   404 -----------------EPVRRQSLTP---------------PPQNTITWEEYISAE---NGKAP 433

  Fly   381 GGPKNLSTKVQR--FRANLWLAEEHPIRLQEQVLPILDLMSTMASPHVSKLRDFITMQLPAGFPV 443
            ...:.|..|..:  |:|.:.:::|.|:.: |.:|.:|::::..  .|.:|||:|:.|:||.||||
  Rat   434 HLGRELVCKESKKTFKATVAMSQEFPLGI-ESLLNVLEVIAPF--KHFNKLREFVQMKLPPGFPV 495

  Fly   444 KVEIPLFHVLNACITF---------GNVFALTTPVDH 471
            |::||:|..:.|.:||         |::||:  |.|:
  Rat   496 KLDIPVFPTITATVTFQEFRCDEFDGSIFAI--PEDY 530

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15118	NP_611396.1	ANK	10..>94	CDD:238125	30/85 (35%)
		ANK repeat	12..38	CDD:293786	4/25 (16%)
		Ank_2	13..94	CDD:289560	28/83 (34%)
		ANK repeat	40..70	CDD:293786	15/29 (52%)
		GPCR_chapero_1	155..497	CDD:288735	90/345 (26%)
		vWFA	<558..627	CDD:294047
Ankrd13c	NP_001178499.2	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D425969at2759
OrthoFinder	1	1.000	-	-		FOG0000585
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.920