DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG15118 and C01F1.6

DIOPT Version :9

Sequence 1:NP_611396.1 Gene:CG15118 / 37199 FlyBaseID:FBgn0034418 Length:637 Species:Drosophila melanogaster
Sequence 2:NP_494753.3 Gene:C01F1.6 / 173761 WormBaseID:WBGene00015301 Length:456 Species:Caenorhabditis elegans


Alignment Length:506 Identity:128/506 - (25%)
Similarity:233/506 - (46%) Gaps:105/506 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly    11 YPLH----WHIWHNELEQLQAAIDQNDKEKIDPRGRTPLMLAVRLANLPCVKCLLAAKCNATYE- 70
            ||||    ::..|:.::.|:|....::|   |..|.|.|.:|..|.:...:..|||.......: 
 Worm    26 YPLHKAAFFNDTHSIVQLLRAGRSLSEK---DTHGNTALHIATMLGHREAIAILLANNAPVRIKN 87

  Fly    71 YEGWSIVQEAVCTGDVDILTAIIEVRDLQRHVQRVTHVPKLLQHLLDAPDFYIEMKWEFTSWVPL 135
            .:||:.:.|:|..||..|:|.::.....|.:.:.....|.|::...|..|||:|.||:|.||:||
 Worm    88 IDGWNPLMESVSYGDRQIITEMLRKLKTQTNEKMSRGKPHLMKMFQDLGDFYMEFKWDFQSWIPL 152

  Fly   136 MSRLCPSDTYKVYKRGANVRIDTTLLGFDNNTWQRGNRSYIFK-GAKETATMIEIDHDTNEVM-- 197
            :||:.|||...:||:|..:|:||||..|....|:||:.:::|. .|.....::.:|:.|....  
 Worm   153 LSRILPSDVCLIYKKGNLLRMDTTLADFSERNWERGDITFLFNVDAPPGEQLVVMDNKTKVFQRG 217

  Fly   198 -VEEMSSDIGDIVAIPPALGTVRARLNAPVITNNIEMDKISFERNKCGIWGWRSEKSEMINGYNC 261
             .||..::|.:.|.:         .::..::..::....:.|::...| |.::..:.|.:..:..
 Worm   218 RREESEAEIDEEVDV---------LMSTDIVNAHMSTKTVGFKQAYSG-WVFKHAREEQMGDFPV 272

  Fly   262 KVYGASNVEFVTKTRMDHLSEEQI-KNKTARTPLHSLLG---IADEDYVSPADAAAALKDRTPSP 322
            ..|....::..|:.|.:||:.:.: |||:.   ||||..   :.|:::       ::|:.|    
 Worm   273 NFYSVEGLKLTTRKRREHLTSDDVKKNKSI---LHSLTSGHTVNDDEF-------SSLQHR---- 323

  Fly   323 RLEEASNAGVENGGRNSPAPG------NQSNGSSAGASGTSTPKSSVTPEEYFTQEFDLHGRDVG 381
                          ::.|.||      .:.:|::.||           |.:            :|
 Worm   324 --------------KSLPPPGRLPTTWEEYSGAAPGA-----------PPQ------------MG 351

  Fly   382 GPKNLSTKVQRFRANLWLAEEHPIRLQEQVLPILDLMSTMAS-PHVSKLRDFITMQLPAGFPVKV 445
            .|:.:.|..::|:|.:.::||.|:    .|..::||:..:|. .|:.|||.|.:.:||.||||.|
 Worm   352 RPQIVKTNEKQFKALVGMSEEFPL----SVDVLVDLLEVVAPFKHLDKLRRFCSARLPPGFPVCV 412

  Fly   446 EIPLFHVLNACITFGNVFALTTPVDHVATLQEQDRVTCLVDDRCFDIPAHY 496
            ||||...:.|.:||                 ::.:.|..:.|:.|.||..|
 Worm   413 EIPLLATIAAKVTF-----------------QKFQFTNDIQDKMFTIPTSY 446

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG15118NP_611396.1 ANK 10..>94 CDD:238125 25/87 (29%)
ANK repeat 12..38 CDD:293786 7/29 (24%)
Ank_2 13..94 CDD:289560 23/85 (27%)
ANK repeat 40..70 CDD:293786 8/29 (28%)
GPCR_chapero_1 155..497 CDD:288735 80/357 (22%)
vWFA <558..627 CDD:294047
C01F1.6NP_494753.3 ANK repeat 27..54 CDD:293786 7/29 (24%)
Ank_2 28..112 CDD:372319 23/86 (27%)
ANK repeat 56..87 CDD:293786 8/30 (27%)
GPCR_chapero_1 172..447 CDD:371788 80/357 (22%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D425969at2759
OrthoFinder 1 1.000 - - FOG0000585
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.920

Return to query results.
Submit another query.