DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment botv and extl2

DIOPT Version :9

Sequence 1:	NP_523790.1	Gene:	botv / 37198	FlyBaseID:	FBgn0027535	Length:	972	Species:	Drosophila melanogaster
Sequence 2:	NP_001070029.1	Gene:	extl2 / 558373	ZFINID:	ZDB-GENE-060929-1122	Length:	332	Species:	Danio rerio

Alignment Length:	264	Identity:	84/264 - (31%)
Similarity:	128/264 - (48%)	Gaps:	43/264 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   710 PREQFTIVMLTYEREQVLMDSLGRLYGLPYLHKVVVVWNSPKPPLDDLRWPDIG---VPVAVLRA 771
            |.|.|||:|.||.|..||:..|.....:|:|..:::|||:|........|.::|   |||.....
Zfish    62 PEESFTIIMQTYNRTDVLLRLLNHYQAVPHLQCIIIVWNNPGETPPRRLWDELGPHPVPVLFREQ 126

  Fly   772 PRNSLNNRFLPFDVIETEAVLSVDDDAHLRHDEILFGFRVWREHRDRVVGFPGRYHAWDLGNPNG 836
            ..|.:.||.:....::|:|||.:|||..|...:|.|.|.||::..|::|||..|.|   :.:.:|
Zfish   127 RVNRMRNRLMMHPDVKTDAVLMLDDDILLSVPDISFAFSVWKQFPDQIVGFVPRKH---VSSASG 188

  Fly   837 QWHYNSNYSCEL-----------SMVLTGAAFVHKYYLYLYTYHLPQAIRDKVDEYMNCEDIAMN 890
            .:.|.   |.||           ||:|.||:|.|:.:|..: ...|..:...:|...||:|||||
Zfish   189 VYSYG---SFELQDPDKGGGDRYSMILVGASFFHRRFLKQF-QEQPAEVHTLLDRTQNCDDIAMN 249

  Fly   891 FLVSHITRKPPVKVTSRWTFRCPGCPVSLS--EDDT------------HFQERHKCINFFSRVFG 941
            |:|:....|.|..|..:        ||.:|  |.|.            |..:|..|:|..::::|
Zfish   250 FIVARQLSKRPSGVFVK--------PVHMSNLEKDASSGFVGMWHRPEHMLQRSYCLNKLAQIYG 306

  Fly   942 YTPL 945
            :.||
Zfish   307 HMPL 310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
botv	NP_523790.1	TBPIP	<107..185	CDD:284512
		Exostosin	224..551	CDD:281069
		Glyco_transf_64	714..949	CDD:286358	82/260 (32%)
extl2	NP_001070029.1	Glyco_transf_64	66..314	CDD:286358	82/260 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D314330at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920