Protein Alignment botv and ext1c

DIOPT Version :10

• Sequence 1: NP_523790.1
• Gene: botv / 37198
• FlyBaseID: FBgn0027535
• Length: 972
• Species: Drosophila melanogaster
• Sequence 2: NP_001035420.1
• Gene: ext1c / 497281
• ZFINID: ZDB-GENE-050211-5
• Length: 737
• Species: Danio rerio
• Alignment Length: 832
• Identity: 245/832 - (29%)
• Similarity: 370/832 - (44%)
• Gaps: 188/832 - (22%)

  Fly   174 QREAVQRNTPDLALPRSLLPNTLPRKSNPITGGMAAS----------------CEMHNCFNHSRC 222
            :|..|.|..||. |.|:||||...:......||...|                |.|..||:..||
Zfish    37 RRGEVPRPWPDW-LDRALLPNFAEQLDLQNGGGPGDSPRQRKQAWSSIYKDSRCRMDTCFDFGRC 100

  Fly   223 SLTSGFPVYLYDPDEHSVQRKGYDIDGFLKTTLKQTLGYNAHIVKDPKHACIYLVLVGEALLEQD 287
            ...|||.||:|.|:      ||..:....:..| .::..:.:...||:.||::  ::|...|::|
Zfish   101 QTQSGFRVYIYPPE------KGERVSESYRKIL-TSVSESRYYTSDPREACLF--VLGIDTLDRD 156

  Fly   288 LLRNNRYAAQEAEHQQPSTPTLENDCPVDMEKLYSLPYWGGDGRNHVLLNLARRDLTSHRTNPLY 352
            .|            .|...|.::       |::...|.| .||||||:.||      ...|.|.|
Zfish   157 QL------------SQQFVPNVD-------ERIRGYPLW-NDGRNHVIFNL------YSGTWPNY 195

  Fly   353 RQ----NTMRAIVVQSAFEREQFRPGYDLIVP------PILGPPGGDVWQECAEMVPARRKYLLT 407
            .:    |..:||:.:::...|.||||:|:.:|      |..|...|  |. ....||.||||||.
Zfish   196 TEDLGFNVGQAILAKASLNTEHFRPGFDISIPLFSKEHPQKGGKRG--WL-VRNSVPPRRKYLLM 257

  Fly   408 YQGELRPKQSSLNPLDAFILEHLADMAKGATQDQFVLQFQCVPATEQQEGDSLPDW-----TLCG 467
            ::|     :..|..:.:.....|..:..|.         ..|..|..:.|   .||     ..|.
Zfish   258 FKG-----KRYLTGIGSDTRNALHHIHNGK---------DIVSLTTCRHG---KDWEKHKDARCD 305

  Fly   468 SDSSR------RQLLKDSTFSLILPPLNGRVSSTLMLARIYEALRSGAVPVILGADELRLPYAET 526
            .|:..      ::||.:|||.|:  |...|:.|    .|..|:|::..:||:| ::...||:::.
Zfish   306 HDNQEYERFDYQELLHNSTFCLV--PRGRRLGS----FRFLESLQAACIPVLL-SNGWELPFSDV 363

  Fly   527 VDWRRTALLLPKARITELHFLLRAVQDADLLLLRRQGRLIWERYLSSVQATVDTVIASLRDRLGI 591
            :.|.:..:...:..:.::...:|||....:|.||:|.:.:|:.|.|||...|.|.:..::||
Zfish   364 IQWNQAVVEGDERLLLQVPSTVRAVGMDRVLALRQQTQTLWDAYFSSVDKIVLTTLEIIKDR--- 425

  Fly   592 PPRPVPSVIAQS--VFNSTFIPLKSDPPVGLDTEPEESLGPIEPPYPSPAFRRNYTILRMQAKEA 654
                |.|.|:::  ::|:.        |.||...||.|......|:
Zfish   426 ----VYSHISRNKLMWNAL--------PGGLLVLPEFSTHLAHYPF------------------- 459

  Fly   655 WNDWLDPFYLYPQLPFDPALPSEAKFMGSHTGFRPIGKGLGGAGKEFGESLGGNYPREQFTIVML 719
                   :||                   |.|..|        |:||...:....|
Zfish   460 -------YYL-------------------HLGISP--------GQEFTAVIHATSP--------- 481

  Fly   720 TYEREQVLMDSLGRLYGLPYLHKVVVVWNSPKPPLDDLRWPDIGVPVAVLRAPRNSLNNRFLPFD 784
            ...:.|.:|..|..:....|..:::::|||.|.|....:||.:.||:.|... |...::||||..
Zfish   482 LVSQSQPIMKLLQVVSKSKYCSQIIILWNSEKSPPQRSKWPPMPVPLTVTDG-RRKTSSRFLPHA 545

  Fly   785 VIETEAVLSVDDDAHLRHDEILFGFRVWREHRDRVVGFPGRYHAWDLGNP-NGQWHYNSNYSCEL 848
            .||||||||:|:|..|...||.|.|.|||...||:||:|.|.|.||   | ...|.|.|.::.|.
Zfish   546 AIETEAVLSLDEDTVLLTSEINFAFHVWRSFPDRIVGYPPRSHFWD---PVKKAWGYTSKWTNEY 607

  Fly   849 SMVLTGAAFVHKYYLYLYTYHLPQAIRDKVDEYMNCEDIAMNFLVSHITRKPPVKVTSRWTFR-- 911
            |::||||||.|:||.:|::::||.::|..||...|||||.||||||.:|..|||||..|..::
Zfish   608 SIILTGAAFYHRYYHHLFSHYLPSSLRALVDHSCNCEDILMNFLVSSVTHLPPVKVAQRKQYKEM 672

  Fly   912 --CPGCPVSLSEDDTHFQERHKCINFFSRVFGYTPLLNTQYRADSILFKTRI 961
              ..|..::...:..||.:|.:|:|.||..|||.||.::|:|.|.:|||..:
Zfish   673 PSLQGTKMAPWANPEHFTQRQECVNTFSSWFGYMPLEHSQFRLDPVLFKDHV 724

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
botv	NP_523790.1	CC_brat-like	106..>179	CDD:475168	1/4 (25%)
		Exostosin	224..551	CDD:397245	86/347 (25%)
		Glyco_transf_64	714..953	CDD:430488	100/243 (41%)
ext1c	NP_001035420.1	Exostosin	103..388	CDD:397245	86/346 (25%)
		Glyco_transf_64	472..716	CDD:430488	102/256 (40%)