Protein Alignment botv and extl3

DIOPT Version :10

• Sequence 1: NP_523790.1
• Gene: botv / 37198
• FlyBaseID: FBgn0027535
• Length: 972
• Species: Drosophila melanogaster
• Sequence 2: NP_001008402.1
• Gene: extl3 / 493783
• ZFINID: ZDB-GENE-041124-2
• Length: 917
• Species: Danio rerio
• Alignment Length: 961
• Identity: 462/961 - (48%)
• Similarity: 613/961 - (63%)
• Gaps: 93/961 - (9%)

  Fly    47 WMRQFRRYKLPMVLLMLLFLV---SCLAYRILSVEQDAPPLDLHRSSPLLDAYEDFSAMRAGDL- 107
            |:  .||.:|..:..||.|::   ..:|:..|:...:|...|          ...|.....|:|
Zfish    15 WV--LRRVRLTWLSFMLFFILVFFPLIAHYYLTTIDEAGGPD----------KRIFGPRPGGELC 67

  Fly   108 -KMRIEEMVRIKSTVSVELRELESRRQKLQSDISQYNQKIEELKQELLREQTELERLKISVEQAQ 171
             ...::::.||:.:||.||.:||::||:|..:|::.|.:||..|:.:...:.:|.:||..:.|.:
Zfish    68 EAKHVQDLCRIRESVSEELLQLEAKRQELNGEIARLNLRIEACKRSIDSAKQDLLQLKNVISQTE 132

  Fly   172 VAQREAVQRNTPDLALPRSLLPNT----LPRKSNPITGGMAASCEMHNCFNHSRCSLTSGFPVYL 232
            .:.:|.:.:|.|.|:||..|||:.    .|...:|      .||.:|:||:::||.||||||||:
Zfish   133 HSYKELMAQNQPKLSLPVRLLPDKDDPGYPPPKSP------QSCRLHSCFDYARCPLTSGFPVYV 191

  Fly   233 YDPDEHSVQRKGYDIDGFLKTTLKQTLGYNAHIVKDPKHACIYLVLVGEALLEQDLLRNNRYAAQ 297
            ||...:.   .|..:|..:|.....::..:.::..:|..||:|:.||||.
Zfish   192 YDTGSYP---WGEKLDPLVKQAFASSVKSSVYVTDNPNIACLYIALVGEI--------------- 238

  Fly   298 EAEHQQPSTPTLENDCPVDMEK-LYSLPYWGGDGRNHVLLNLARRDLTSHRTNPLYRQNTMRAIV 361
               .:.||:|...   |.|:|| |.:||||..||.||:|::|:...||.   |.||..:|.||.|
Zfish   239 ---QESPSSPLAS---PSDLEKQLKALPYWRSDGHNHLLVHLSINSLTQ---NFLYNVSTGRAAV 294

  Fly   362 VQSAFEREQFRPGYDLIVPPILGPPGGDVWQECAEMVPARRKYLLTYQGE-LRPKQSSL--NPLD 423
            .||.|...|:|.|:||:|.|::.......:.|....||.:||||.|:||| :...:|||  .|..
Zfish   295 AQSTFFERQYREGFDLVVSPLVHALSEPNFLEVPPQVPVKRKYLFTFQGEKVESLRSSLLEAPPQ 359

  Fly   424 AFILEHLAD--------------MAKGATQDQFVLQFQCVPATEQQEGDSLP-DWTLCGSDSSRR 473
            :|..|...|              ..:.:..||.:::|.|    :.|...||| :|.|||....|.
Zfish   360 SFEEEMEGDPPADYDDRIIGTLKAVQDSHLDQVLVEFTC----KNQAKPSLPTEWALCGKREDRL 420

  Fly   474 QLLKDSTFSLILPPLNGR-VSSTLMLARIYEALRSGAVPVILGADELRLPYAETVDWRRTALLLP 537
            ::||.|||:|::.|.:|: |:|.....|::|||..||:||:|| |..:|||...:.|....:::|
Zfish   421 EVLKVSTFALVISPGDGQLVASAGCSMRLFEALEVGAIPVVLG-DHSKLPYHHLIRWSEAVIMVP 484

  Fly   538 KARITELHFLLRAVQDADLLLLRRQGRLIWERYLSSVQATVDTVIASLRDRLGIPPRPVPSVIAQ 602
            |.||||||||||::.|.|||.:|||||.:||.|.|:.::..:|::||:|..:.||..|:....||
Zfish   485 KPRITELHFLLRSISDNDLLAMRRQGRFLWETYFSTSESIFNTILASVRTSIQIPAAPIREEPAQ 549

  Fly   603 SVFNSTFIPLKSDPPVGLDTEPEES----LGP--IEPPYPSPAFRRNYTILRMQAKEAWNDWLDP 661
            .      ||.|:....|.|....::    |||  :||||.||.|.||:|.........||....|
Zfish   550 E------IPHKAGKLAGTDANLADNGDLDLGPVEVEPPYASPRFLRNFTYTAADVYRTWNRAPGP 608

  Fly   662 FYLYPQLPFDPALPSEAKFMGSHTGFRPIGKGLGGAGKEFGESLGGNYPREQFTIVMLTYEREQV 726
            |:|:|..|.||.|||||||:||.|||||||.|.||:||||..:||||.||||||:||||||||:|
Zfish   609 FHLFPHTPLDPVLPSEAKFLGSGTGFRPIGGGSGGSGKEFQAALGGNVPREQFTVVMLTYEREEV 673

  Fly   727 LMDSLGRLYGLPYLHKVVVVWNSPKPPLDDLRWPDIGVPVAVLRAPRNSLNNRFLPFDVIETEAV 791
            ||:||.||.|||||:||||||||||||.|||.|||||:|:.|:|..:|||||||||:|.|||||:
Zfish   674 LMNSLERLNGLPYLNKVVVVWNSPKPPSDDLLWPDIGLPIVVVRTGKNSLNNRFLPWDAIETEAI 738

  Fly   792 LSVDDDAHLRHDEILFGFRVWREHRDRVVGFPGRYHAWDLGNPNGQWHYNSNYSCELSMVLTGAA 856
            ||:|||||||||||:||||||||.|||:||||||:|||||.:.:  |.|||||||||||||||||
Zfish   739 LSIDDDAHLRHDEIMFGFRVWREARDRIVGFPGRFHAWDLNHQS--WLYNSNYSCELSMVLTGAA 801

  Fly   857 FVHKYYLYLYTYHLPQAIRDKVDEYMNCEDIAMNFLVSHITRKPPVKVTSRWTFRCPGCPVSLSE 921
            |.||||.|||:|.:|:||||.||||:|||||||||||||||||||:||||||||||||||.:||.
Zfish   802 FFHKYYAYLYSYVMPRAIRDMVDEYINCEDIAMNFLVSHITRKPPIKVTSRWTFRCPGCPQALSH 866

  Fly   922 DDTHFQERHKCINFFSRVFGYTPLLNTQYRADSILFKTRIPHDKQKCFKYI 972
            ||:||.|||||||||.:|:||.|||.||:|.||:|||||:||||.||||:|
Zfish   867 DDSHFHERHKCINFFVKVYGYMPLLYTQFRVDSVLFKTRLPHDKTKCFKFI 917

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
botv	NP_523790.1	CC_brat-like	106..>179	CDD:475168	22/74 (30%)
		Exostosin	224..551	CDD:397245	126/346 (36%)
		Glyco_transf_64	714..953	CDD:430488	188/238 (79%)
extl3	NP_001008402.1	ADIP	<79..>143	CDD:463295	19/63 (30%)
		Exostosin	183..498	CDD:397245	126/346 (36%)
		Glyco_transf_64	661..898	CDD:430488	188/238 (79%)