Protein Alignment botv and extl3

DIOPT Version :10

• Sequence 1: NP_523790.1
• Gene: botv / 37198
• FlyBaseID: FBgn0027535
• Length: 972
• Species: Drosophila melanogaster
• Sequence 2: NP_001008036.1
• Gene: extl3 / 493398
• XenbaseID: XB-GENE-855819
• Length: 919
• Species: Xenopus tropicalis
• Alignment Length: 991
• Identity: 477/991 - (48%)
• Similarity: 630/991 - (63%)
• Gaps: 120/991 - (12%)

  Fly    20 GSGGGNEACAPNSSSAQIRHSMGFRTSWMRQFRRYKLPMVLLMLLFLVSCLAYRILSVEQDAPPL 84
            |.|.|.:..       .:|.|...|.||        |...|.::|.....:|:..|:...||...
 Frog    11 GLGNGGQPW-------MLRWSSRIRLSW--------LSFTLFIILVFFPLIAHYYLTTIDDANDP 60

  Fly    85 DLHRSSPLLDAYEDFSAMRAG----DLKMRIEEMVRIKSTVSVELRELESRRQKLQSDISQYNQK 145
            |.....|           |.|    ::| .::::.||:.:||.||.:||::||:|.|:|::.|.|
 Frog    61 DRRIFGP-----------RTGNELCEVK-HVQDLCRIRESVSEELLQLEAKRQELNSEIAKLNLK 113

  Fly   146 IEELKQELLREQTELERLKISVEQAQVAQREAVQRNTPDLALPRSLLPN------TLPRKSNPIT 204
            ||..|:.:...:.:|.:||..:.|.:.:.:|.:.:|.|.|:||..|||.      .||:...
 Frog   114 IEACKKSIENAKQDLLQLKNVISQTEHSYKELMAQNQPKLSLPIRLLPEKDDINIPLPKSKR--- 175

  Fly   205 GGMAASCEMHNCFNHSRCSLTSGFPVYLYDPDEHSVQRKGYDIDGFLKTTLKQTLGYNAHIVKDP 269
                 :|.:||||::|||.|||||||::|:.|::..   |..||..:|..|:.::..|.::.::.
 Frog   176 -----NCGLHNCFDYSRCPLTSGFPVFVYNSDQYPF---GNFIDPLIKQALEASVRNNVYVTENA 232

  Fly   270 KHACIYLVLVGEALLEQDLLRNNRYAAQEAEHQQPSTPTLENDCPVDM-EKLYSLPYWGGDGRNH 333
            .:||||:||:||.                   |:|..|.     |.:: |:|:|||||..||.||
 Frog   233 NNACIYVVLMGEM-------------------QEPVMPK-----PTELEEQLHSLPYWRTDGHNH 273

  Fly   334 VLLNLARRDLTSHRTNPLYRQNTMRAIVVQSAFEREQFRPGYDLIVPPILGPPGGDVWQECAEMV 398
            :::||:|:   |...|.||..:|.||::.||.|...|:|||:|::|.|::.......:.|....|
 Frog   274 LIINLSRK---SETQNYLYNVSTGRAMIAQSTFYDLQYRPGFDIVVSPLVHAMSEPNFLEIPPQV 335

  Fly   399 PARRKYLLTYQGE-LRPKQSSLNPLDAFILEHLADMAKG-----------ATQD---QFVL-QFQ 447
            |.:||||.::||| :...:|||....:| .|.:...|..           |.||   .||: :|.
 Frog   336 PVKRKYLFSFQGEKIESLRSSLQEARSF-EEEMEGNAPADYDDRIITTLKAVQDSKLDFVMVEFT 399

  Fly   448 CVPATEQQEGDSLP-DWTLCGSDSSRRQLLKDSTFSLILPPLNGR-VSSTLMLARIYEALRSGAV 510
            |    :.|...||| :|.|||....|.:|||.|||:||:.|.:.: |.|.....|::|||..||:
 Frog   400 C----KNQAKPSLPTEWALCGERDDRLELLKQSTFALIITPGDSQLVISAGSAMRLFEALEVGAI 460

  Fly   511 PVILGADELRLPYAETVDWRRTALLLPKARITELHFLLRAVQDADLLLLRRQGRLIWERYLSSVQ 575
            ||||| ::::|||.:|:.|....|:|||.||||:|||||::.|.|||.||||||.:||.|.|:..
 Frog   461 PVILG-EQVQLPYHDTIRWNEAVLILPKPRITEVHFLLRSISDNDLLSLRRQGRFLWETYFSTSD 524

  Fly   576 ATVDTVIASLRDRLGIPPRPV---PSVIAQSVFNSTFIPLKSDPPVGLDTEPEES----LGPI-- 631
            ...:|::|::|.|:.||..|:   |:|         .||.:|....|.|....::    |||:
 Frog   525 TVFNTILATVRTRIQIPAAPIKEEPAV---------EIPHRSGKAAGTDPNMADNGDLDLGPVET 580

  Fly   632 EPPYPSPAFRRNYTILRMQAKEAWNDWLDPFYLYPQLPFDPALPSEAKFMGSHTGFRPIGKGLGG 696
            ||||.||.:.||:|:........||....||:|:|..||||.|||||||:||.|||||||.|.||
 Frog   581 EPPYASPKYLRNFTLTAADIYRNWNTAPGPFHLFPHTPFDPLLPSEAKFLGSGTGFRPIGGGAGG 645

  Fly   697 AGKEFGESLGGNYPREQFTIVMLTYEREQVLMDSLGRLYGLPYLHKVVVVWNSPKPPLDDLRWPD 761
            :||||..:||||.||||||:||||||||:|||:||.||.|||||:||||||||||.|.:||.|||
 Frog   646 SGKEFQAALGGNVPREQFTVVMLTYEREEVLMNSLERLNGLPYLNKVVVVWNSPKLPSEDLLWPD 710

  Fly   762 IGVPVAVLRAPRNSLNNRFLPFDVIETEAVLSVDDDAHLRHDEILFGFRVWREHRDRVVGFPGRY 826
            ||||:.::|..:|||||||||:|.||||||||:|||||||||||:||||||||.|||:|||||||
 Frog   711 IGVPIVIVRTEKNSLNNRFLPWDQIETEAVLSIDDDAHLRHDEIMFGFRVWREARDRIVGFPGRY 775

  Fly   827 HAWDLGNPNGQWHYNSNYSCELSMVLTGAAFVHKYYLYLYTYHLPQAIRDKVDEYMNCEDIAMNF 891
            ||||:  |:..|.||||||||||||||||||.||||.|||:|.:||||||.||||:|||||||||
 Frog   776 HAWDI--PHRSWLYNSNYSCELSMVLTGAAFFHKYYAYLYSYVMPQAIRDMVDEYINCEDIAMNF 838

  Fly   892 LVSHITRKPPVKVTSRWTFRCPGCPVSLSEDDTHFQERHKCINFFSRVFGYTPLLNTQYRADSIL 956
            ||||||||||:||||||||||||||.:||.||:||.|||||||||.:|:||.|||.||:|.||:|
 Frog   839 LVSHITRKPPIKVTSRWTFRCPGCPQALSHDDSHFHERHKCINFFVKVYGYMPLLYTQFRVDSVL 903

  Fly   957 FKTRIPHDKQKCFKYI 972
            ||||:||||.||||:|
 Frog   904 FKTRLPHDKTKCFKFI 919

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
botv	NP_523790.1	CC_brat-like	106..>179	CDD:475168	24/72 (33%)
		Exostosin	224..551	CDD:397245	130/345 (38%)
		Glyco_transf_64	714..953	CDD:430488	189/238 (79%)
extl3	NP_001008036.1	TPR_MLP1_2	<71..150	CDD:462316	24/79 (30%)
		Exostosin	190..500	CDD:397245	130/345 (38%)
		Glyco_transf_64	663..900	CDD:430488	189/238 (79%)