DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment botv and extl2

DIOPT Version :9

Sequence 1:	NP_523790.1	Gene:	botv / 37198	FlyBaseID:	FBgn0027535	Length:	972	Species:	Drosophila melanogaster
Sequence 2:	XP_012816366.1	Gene:	extl2 / 493327	XenbaseID:	XB-GENE-1001404	Length:	325	Species:	Xenopus tropicalis

Alignment Length:	297	Identity:	91/297 - (30%)
Similarity:	134/297 - (45%)	Gaps:	50/297 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   680 FMGSHTGFRPIGKGLGGAGKEFGESLGGNYPREQFTIVMLTYEREQVLMDSLGRLYGLPYLHKVV 744
            |:|:.|...|........|...|..|....|::.||::|.||.|..:|:..|.....:|.|..|:
Frog    26 FLGALTALLPATNEDAVVGVRRGIPLSAVSPKDVFTLIMQTYNRTDLLLKMLNHYQAMPGLSHVI 90

  Fly   745 VVWNSPKPPLDDLRWPDIG---VPVAVLRAPRNSLNNRFLPFDVIETEAVLSVDDDAHLRHDEIL 806
            ||||:.........|...|   |||...:...|.:.||...|..|:|:|||.:|||..:...:|.
Frog    91 VVWNNVGQDTPQELWESFGPHPVPVTFKKQKVNLMRNRLQSFPEIQTQAVLMMDDDTLVSAYDIS 155

  Fly   807 FGFRVWREHRDRVVGFPGRYHAWDLGNPNGQWHYNSNYSCEL-----------SMVLTGAAFVHK 860
            |.|.:|::..||:|||..|.|   :.:|:|.:.|.   |.||           ||:|.||||.|.
Frog   156 FAFSIWQQFPDRIVGFVPRKH---VSSPSGIYSYG---SFELKAPHTETGDMYSMILIGAAFFHS 214

  Fly   861 YYLYLYTYHLPQAIRDKVDEYMNCEDIAMNFLV-SHITRKPPVKV----------------TSRW 908
            .||.|:. .||.::.:.:|:..||:||||||:| :|:.:...|.|                |..|
Frog   215 DYLRLFE-QLPASVHNMIDQTQNCDDIAMNFMVANHLGKASGVLVKPTDMRNLEKEAGSGYTGMW 278

  Fly   909 TFRCPGCPVSLSEDDTHFQERHKCINFFSRVFGYTPL 945
                        ....|..:|..|:|..:.::...||
Frog   279 ------------HRAEHLLQRSFCLNKLAEIYSTMPL 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
botv	NP_523790.1	TBPIP	<107..185	CDD:284512
		Exostosin	224..551	CDD:281069
		Glyco_transf_64	714..949	CDD:286358	83/263 (32%)
extl2	XP_012816366.1	Glyco_transf_64	60..311	CDD:401264	83/263 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D314330at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010