DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment botv and LOC101885478

DIOPT Version :9

Sequence 1:	NP_523790.1	Gene:	botv / 37198	FlyBaseID:	FBgn0027535	Length:	972	Species:	Drosophila melanogaster
Sequence 2:	XP_017208153.1	Gene:	LOC101885478 / 101885478	-ID:	-	Length:	745	Species:	Danio rerio

Alignment Length:	805	Identity:	226/805 - (28%)
Similarity:	373/805 - (46%)	Gaps:	176/805 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   188 PRSLLPNTLPRKSNPITGGMAAS--CEMHNCFNHSRCSLTSGFPVYLYDPDEHSVQRKGYDIDGF 250
            |..|..:|.||:...|...:..|  |.|..||:..||.  .||.:|:|.|.:..|..:.|.   .
Zfish    73 PLLLHQHTSPRERREIQKNIYKSRRCRMDTCFDFQRCE--RGFKIYVYPPQKGEVPSESYQ---K 132

  Fly   251 LKTTLKQTLGYNAHIVKDPKHACIYLVLVGEALLEQDLLRNNRYAAQEAEHQQPSTPTLENDCPV 315
            :...::::..|..    ||..||::::.:       |.|..::.:||...:.:
Zfish   133 ILAAIEESRFYTT----DPNEACLFVLSI-------DTLDRDQLSAQYVHNVR------------ 174

  Fly   316 DMEKLYSLPYWGGDGRNHVLLNLARRDLTSHRTNPLYRQ----NTMRAIVVQSAFEREQFRPGYD 376
              .::.|||.| .:||||::.||      ...|.|.|.:    :..:|::.:::.:.:.|||.:|
Zfish   175 --ARIQSLPLW-YEGRNHLIFNL------YSGTWPDYTEELGFDIGQAMLAKASTDMDNFRPHFD 230

  Fly   377 LIVP------PILGPPGGDVWQECAEMVPARRKYLLTYQGELRPKQSSLNPLDAFILEHLADMAK 435
            :.:|      |   ..|||........||..|||||.::|     :..|..:.:.....|..:..
Zfish   231 ISIPLFSKDHP---QKGGDKGFLNLNNVPPLRKYLLVFKG-----KRYLTGIGSETRNALYHIHN 287

  Fly   436 GATQDQFVLQFQCVPATEQQEGDSLPDW-----TLCGSDSSR------RQLLKDSTFSLILPPLN 489
            |   |..:|...|      :.|   .||     ..|..|:..      ::||.:|:|.|:  |..
Zfish   288 G---DDIILLTTC------KHG---KDWEKHKDARCDRDNEEYTKFDYQELLHNSSFCLV--PRG 338

  Fly   490 GRVSSTLMLARIYEALRSGAVPVILGADELRLPYAETVDWRRTALLLPKARITELHFLLRAVQDA 554
            .|:.|    .|..|||::..:||:| ::...||::|.:||.:.|::..:..:.::..:.|:|...
Zfish   339 RRLGS----FRFLEALQAACIPVLL-SNGWELPFSEVIDWSKAAIIGDERLLLQVPSITRSVGSD 398

  Fly   555 DLLLLRRQGRLIWERYLSSVQATVDTVIASLRDRLGIPPRPVPSVIAQSVFNSTFIPLKSDPPVG 619
            .:|.||:|.:.:|:.|.|||...|.|.:..:.||:    |...| .::.::||.        |.|
Zfish   399 RILALRQQTQFLWDAYFSSVTKIVLTTLEIVHDRI----RTHMS-RSRQMWNSL--------PGG 450

  Fly   620 LDTEPEESLGPIEPPYPSPAFRRNYTILRMQAKEAWNDWLDPFYLYPQLPFDPALPSEAKFMGSH 684
            |              |..|.|..:.::.             |||
Zfish   451 L--------------YALPEFSSDLSLF-------------PFY--------------------- 467

  Fly   685 TGFRPIGKGLGGAGKEFGESLGGNYPREQFTIVM--LT--YEREQVLMDSLGRLYGLPYLHKVVV 745
              :..:||.                |.::||.::  ||  ..::|.:...:..:....:..:::|
Zfish   468 --YSTLGKS----------------PPQEFTAIIQALTPLQSQQQPIFKLIHAVAKSKFCVQILV 514

  Fly   746 VWNSPKPPLDDLRWPDIGVPVAVLRAPRNSLNNRFLPFDVIETEAVLSVDDDAHLRHDEILFGFR 810
            :||..|||....:||.|..|.:::...|.:::.||.|...|:|:||||:|:|:.|..:|:.|.|.
Zfish   515 LWNCEKPPPPRNKWPSITTPFSIIEGKRKTMSGRFYPHQAIKTDAVLSLDEDSVLSTNEVDFAFI 579

  Fly   811 VWREHRDRVVGFPGRYHAWDLGNPNGQWHYNSNYSCELSMVLTGAAFVHKYYLYLYTYHLPQAIR 875
            ||:...||:||:|.|.|.||.|  .|:|.|.|.::.|.|||||||||.|:||.:|||::||.::.
Zfish   580 VWQSFPDRIVGYPARSHYWDSG--KGRWGYTSKWTNEYSMVLTGAAFYHRYYHHLYTHYLPMSLL 642

  Fly   876 DKVDEYMNCEDIAMNFLVSHITRKPPVKVTS----RWTFRCPGCPVSLSEDDTHFQERHKCINFF 936
            ..||:..|||||.:|||:|.:|:.||:|||.    :.|....|...|...|..||.:|..|:|.|
Zfish   643 SMVDQLANCEDILINFLISAVTKLPPIKVTQKKQYKETMMQQGSKASRWADPDHFAQRQSCMNSF 707

  Fly   937 SRVFGYTPLLNTQYRADSILFKTRI 961
            :..||:.|||::|.|.|.:|||.::
Zfish   708 TSWFGFMPLLHSQLRLDPVLFKDQV 732

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
botv	NP_523790.1	TBPIP	<107..185	CDD:284512
		Exostosin	224..551	CDD:281069	80/347 (23%)
		Glyco_transf_64	714..949	CDD:286358	97/242 (40%)
LOC101885478	XP_017208153.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D314330at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010