DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG15117 and beta-Man

DIOPT Version :9

Sequence 1:	NP_725851.1	Gene:	CG15117 / 37197	FlyBaseID:	FBgn0034417	Length:	670	Species:	Drosophila melanogaster
Sequence 2:	NP_001246899.1	Gene:	beta-Man / 40524	FlyBaseID:	FBgn0037215	Length:	908	Species:	Drosophila melanogaster

Alignment Length:	587	Identity:	124/587 - (21%)
Similarity:	214/587 - (36%)	Gaps:	147/587 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 LSKSRPTIPMPVPASYNDITTDNLRDHVGTVW--YDRKFFVPRSWSKD------QRIWLRFGSVH 145
            |:.:..|:|:.:.:::.....|:..| ||..:  || .|.....:..|      ..|.|.|..:.
  Fly    51 LTIANQTLPLGIYSAFAPQVLDSYND-VGLRYLAYD-NFTFSNFFQFDVHHFNRGHINLTFHGID 113

  Fly   146 YEAYVWINGQKVVKHEMGHLPFEAEVTDLLSYGAENRITVMCDNALI------------QTTVPQ 198
            ..:.:.:|.|.:.:.:...:.:..||:.||.  |||.:.|...:.::            :.:||
  Fly   114 TVSEIRLNHQLLGRTDNMFVRYSYEVSSLLQ--AENFLEVEIQSPVVAALARANALKEAKKSVP- 175

  Fly   199 GRITEVPNDG-----GMTIVQ----SYTFDF---FNYAGIHRSVHLYTTPRTFIEEVEVTTNLSK 251
               .|.||:.     .|.:::    |:::|:   ...|||.::|.|.......|.||:|..
  Fly   176 ---PECPNERYHGECHMNMLRKMQASFSWDWGPAAPSAGIWKNVELEIYEVAVIREVDVDV---- 233

  Fly   252 DATVGEVFYSVSVN-----GSAANEADNVLQIQANLYDK----DGILVANATS-------DQKL- 299
             :.|...::::.:.     |...|....::.....|.|:    |...:.|.:.       ||.:
  Fly   234 -SRVNGSYWNMHIRCFLDAGGWQNFNGRLVLYAVELLDRPVVVDRYAIKNISHLAPVIEFDQAVP 297

  Fly   300 GGKLQVNPVKPWWPYLMHSEPGY----LYQLEIKLLA--------TNDELLDVYRLKVGIRTLS- 351
            .||     |..|||      .||    ||.|...|..        ...:......|:||.|||.
  Fly   298 NGK-----VVTWWP------NGYGEQKLYPLHFTLKTWLGPDGPEVRSKTKSHKSLRVGFRTLDL 351

  Fly   352 ---------WNSQQFLINGKPVYFRGFGRHEDSDIRGKGLDN---ALMVRD-----FNLLKWIGA 399
                     .|:..|.:||..::.:| ..:..|.:..:...|   :.::|.     .|:|:..|.
  Fly   352 VEDPAPDGVGNTFLFRVNGVEMFMKG-SNYIPSHLLPEMQTNEQISHLLRSAKEAHMNMLRVWGG 415

  Fly   400 NAYRTSHYPYSEESMQFADEHGIMIIDE----CPSVDTENFSQELLGKHKSSLEQLIHRDRNHPS 460
            ..|.:.::      .|.||..|::|..:    |.....   :.|.|...:..:.|...|..:|||
  Fly   416 GVYESDYF------YQLADSLGLLIWQDMMFACAMYPV---NDEFLSSVREEVRQNAMRLSHHPS 471

  Fly   461 VVMWSIANEPRTGSVS------------ADSYFEL-VANFTRSL----DKTRPITAAIAVSNTQD 508
            |.::...||.....|.            ...|.|| :||....|    ..:||.....:.||  .
  Fly   472 VAIFVTNNENEAALVQNWYGTLFERDRFESEYRELYLANVIHELKLVSHSSRPQPLVSSPSN--G 534

  Fly   509 KAGRSLDIISFNRYNAWYSNAGRLDMITQNVIDEAIAWNKRYNKPIIMSEYGADTLEGLHMQPAY 573
            ||....:.||.|..:....:....| .|::..|..|     :.:|..:||:|..:..|     ||
  Fly   535 KASEPDNYISSNPQDNQNGDVHFYD-YTKDGWDPGI-----FPRPRFVSEFGFQSFPG-----AY 588

  Fly   574 VW 575
            .|
  Fly   589 AW 590

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15117	NP_725851.1	PRK10150	48..648	CDD:236657	124/587 (21%)
		Glyco_hydro_2_N	57..236	CDD:280926	37/178 (21%)
		Glyco_hydro_2	238..348	CDD:279093	28/138 (20%)
		Glyco_hydro_1	356..645	CDD:304882	55/249 (22%)
beta-Man	NP_001246899.1	LacZ	102..>720	CDD:225789	113/534 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45454795
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3250
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740