DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15117 and Gusb

DIOPT Version :9

Sequence 1:	NP_725851.1	Gene:	CG15117 / 37197	FlyBaseID:	FBgn0034417	Length:	670	Species:	Drosophila melanogaster
Sequence 2:	NP_058711.3	Gene:	Gusb / 24434	RGDID:	2772	Length:	648	Species:	Rattus norvegicus

Alignment Length:	640	Identity:	295/640 - (46%)
Similarity:	414/640 - (64%)	Gaps:	34/640 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 VLHFSIALILVNKEVPQTRGMLYPRESETREVRSLDGIWNFVRSDQA-NPTQGVRDEWYAKELSK 91
            |..|.:..:|.:..:....|||:|:|:.:||::.|||:|:| |:|.: |..||...:||.:.|.:
  Rat     7 VCWFVLGQLLCSCALALQGGMLFPKETPSRELKVLDGLWSF-RADYSNNRLQGFEKQWYRQPLRE 70

  Fly    92 SRPTIPMPVPASYNDITTD-NLRDHVGTVWYDRKFFVPRSWSK--DQRIWLRFGSVHYEAYVWIN 153
            |.||:.||||:|:||||.: .||:.:|.|||:|:..:|:.|::  |:|:.||..|.||.|.||:|
  Rat    71 SGPTLDMPVPSSFNDITQEAELRNFIGWVWYEREAVLPQRWTQDTDRRVVLRINSAHYYAVVWVN 135

  Fly   154 GQKVVKHEMGHLPFEAEVTDLLSYG--AENRITVMCDNALIQTTVPQGRITEVPNDGGM----TI 212
            |..||:||.|||||||::|.|:..|  ...|:|:..:|.|...|:|.|.|. ...|..|    ..
  Rat   136 GIHVVEHEGGHLPFEADITKLVQSGPLTTFRVTIAINNTLTPYTLPPGTIV-YKTDPSMYPKGYF 199

  Fly   213 VQSYTFDFFNYAGIHRSVHLYTTPRTFIEEVEVTTNLSKDATVGEVFYSVSVNGSAANEADNVLQ 277
            ||..:||||||||:||||.|||||.|:|:::.|||::.:|  ||.|.|.:||.||      :..|
  Rat   200 VQDISFDFFNYAGLHRSVVLYTTPTTYIDDITVTTDVDRD--VGLVNYWISVQGS------DHFQ 256

  Fly   278 IQANLYDKDGILVANATSDQKLGGKLQVNPVKPWWPYLMHSEPGYLYQLEIKLLATNDELLDVYR 342
            ::..|.|:||.:||..|.::   |:|:|.....|||||||..|.|||.||: .:.|.:.:.|.|.
  Rat   257 LEVRLLDEDGKIVARGTGNE---GQLKVPRAHLWWPYLMHEHPAYLYSLEV-TMTTPESVSDFYT 317

  Fly   343 LKVGIRTLSWNSQQFLINGKPVYFRGFGRHEDSDIRGKGLDNALMVRDFNLLKWIGANAYRTSHY 407
            |.|||||::....:|||||||.||:|..:||||||||:|.|..|:::|||||:|:|||::|||||
  Rat   318 LPVGIRTVAVTKSKFLINGKPFYFQGVNKHEDSDIRGRGFDWPLLIKDFNLLRWLGANSFRTSHY 382

  Fly   408 PYSEESMQFADEHGIMIIDECPSVD---TENFSQELLGKHKSSLEQLIHRDRNHPSVVMWSIANE 469
            |||||.:|..|.:||::|||||.|.   .::|....|..|...:::|:.||:|||:|||||:|||
  Rat   383 PYSEEVLQLCDRYGIVVIDECPGVGIVLPQSFGNVSLRHHLEVMDELVRRDKNHPAVVMWSVANE 447

  Fly   470 PRTGSVSADSYFELVANFTRSLDKTRPITAAIAVSNTQ---DKAGRSLDIISFNRYNAWYSNAGR 531
            |.:....|..||:.:...|::||.|||:|   .||||:   |.....:|:|..|.|.:||.:.|.
  Rat   448 PVSSLKPAGYYFKTLIAHTKALDPTRPVT---FVSNTRYDADLGAPYVDVICVNSYLSWYHDYGH 509

  Fly   532 LDMITQNVIDEAIAWNKRYNKPIIMSEYGADTLEGLHMQPAYVWSEEFQTEVFSRHFKAFDELRK 596
            |::|...:..:...|.|.|.||||.||||||.:.|||..|..::|||:||.:...:....||.||
  Rat   510 LEVIQLQLTSQFENWYKMYQKPIIQSEYGADAVSGLHEDPPRMFSEEYQTALLENYHLILDEKRK 574

  Fly   597 KGWFIGEFVWNFADFKTAQSYTRVGGNKKGVFTRARQPKAAAHLLRKRYFALGRD 651
            : :.|||.:||||||.|.||..||.|||||:|||.|.||.||.:||:||:.:..:
  Rat   575 E-YVIGELIWNFADFMTNQSPLRVTGNKKGIFTRQRNPKMAAFILRERYWRIANE 628

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15117	NP_725851.1	PRK10150	48..648	CDD:236657	291/615 (47%)
		Glyco_hydro_2_N	57..236	CDD:280926	89/188 (47%)
		Glyco_hydro_2	238..348	CDD:279093	44/109 (40%)
		Glyco_hydro_1	356..645	CDD:304882	147/294 (50%)
Gusb	NP_058711.3	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166338618
Domainoid	1	1.000	304	1.000	Domainoid score	I1331
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37271
Inparanoid	1	1.050	563	1.000	Inparanoid score	I1043
OMA	1	1.010	-	-		QHG61039
OrthoDB	1	1.010	-	-		D153017at33208
OrthoFinder	1	1.000	-	-		FOG0002553
OrthoInspector	1	1.000	-	-		otm44730
orthoMCL	1	0.900	-	-		OOG6_104811
Panther	1	1.100	-	-	LDO	PTHR10066
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3251
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	13.910