DRSC/TRiP Functional Genomics Resources

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Protein Alignment 5-HT1A and or90j1

DIOPT Version :9

Sequence 1:NP_001356890.1 Gene:5-HT1A / 37196 FlyBaseID:FBgn0004168 Length:846 Species:Drosophila melanogaster
Sequence 2:NP_001077338.1 Gene:or90j1 / 797763 ZFINID:ZDB-GENE-070806-32 Length:306 Species:Danio rerio


Alignment Length:256 Identity:50/256 - (19%)
Similarity:91/256 - (35%) Gaps:81/256 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly   220 FTQLLRMAVTSVLLG--LMILVTIIGNVFVIAAIILERNLQNVANYLVASLA--VADLFVA---- 276
            :|||:...:.::.:|  |.:...::.|:.|....:|.....||......:||  ..:.|||    
Zfish    54 YTQLIINDIITLSVGVTLYVFTCLLPNLNVAICCVLVLIASNVFKNTPLNLAGMAIERFVAVCYP 118

  Fly   277 ------CLV----MPLGAVYEISQGWILG--PELCDIWTSCDVLCCTASILHLVAIAV------- 322
                  |.|    :.:|.:      |::|  |.:.|.               ||.:|:       
Zfish   119 LHHAQICTVQNTKILIGII------WLMGALPGMLDF---------------LVVLALRPLSFFT 162

  Fly   323 -DRYWAVTNI-DYIHSRTSNRVFMMIF-C-VWTAAVIVSLAPQFGWK----DPDYLQR------- 372
             :|...:.|: |:.:...|:.||.::: | ||...........|..|    :|...|:       
Zfish   163 SNRICFLQNVFDFEYHVISHAVFNIVYMCSVWVLLFYTYFKVLFSAKAAASEPAQAQKARRTILL 227

  Fly   373 --IEQQKC------------MVSQDVSYQVFATCCTF----YVPLLVILALYWKIYQTARK 415
              ::...|            :.|:...|:.....|||    .:|.|:...:|....||.:|
Zfish   228 HGVQLLLCTLSLLTTVLDGALTSRFPDYRQIIYYCTFILTSILPRLLSPLIYGLRDQTFKK 288

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
5-HT1ANP_001356890.1 7tmA_5-HT1A_invertebrates 227..>413 CDD:320454 45/245 (18%)
TM helix 1 228..254 CDD:320454 4/27 (15%)
TM helix 2 261..287 CDD:320454 8/41 (20%)
TM helix 3 299..329 CDD:320454 5/37 (14%)
TM helix 4 340..362 CDD:320454 5/23 (22%)
TM helix 5 383..412 CDD:320454 7/32 (22%)
7tm_GPCRs <743..816 CDD:355774
TM helix 6 747..772 CDD:341315
TM helix 7 784..809 CDD:341315
or90j1NP_001077338.1 7tm_4 19..>140 CDD:304433 19/91 (21%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24247
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
11.100

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