| Sequence 1: | NP_001356890.1 | Gene: | 5-HT1A / 37196 | FlyBaseID: | FBgn0004168 | Length: | 846 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_076917.1 | Gene: | HTR5A / 3361 | HGNCID: | 5300 | Length: | 357 | Species: | Homo sapiens |
| Alignment Length: | 625 | Identity: | 148/625 - (23%) |
|---|---|---|---|
| Similarity: | 219/625 - (35%) | Gaps: | 298/625 - (47%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 211 TTSKVAEDDF---TQLLRM--AVTSVLLGLMILVTIIGNVFVIAAIILERNLQNVANYLVASLAV 270
Fly 271 ADLFVACLVMPLGAVYEIS-QGWILGPELCDIWTSCDVLCCTASILHLVAIAVDRYWAVT-NIDY 333
Fly 334 -IHSR--TSNRVFMMIFCVWTAAVIVSLAP-QFGWKDPDYLQRIEQQKCMVSQDVSYQVFATCCT 394
Fly 395 FYVPLLVILALYWKIYQTARKRIHRRRPRPVDAAVNNNQPDGGAATDTKLHRLRLRLGRFSTAKS 459
Fly 460 KTGSAVGVSGPASGGRALGLVDGNSTNTVNTVEDTEFSSSNVDSKSRAGVEAPSTSGNQIATVSH 524
Fly 525 LVALAKQQGKSTAKSSAAVNGMAPSGRQEDDGQRPEHGEQEDREELEDQDEQVGPQPTTATSAMT 589
Fly 590 AAGTNESEDQCKANGVEVLEDPQLQQQLEQVQQLQKSVKSGGGGGASTSNATTITSISALSPQTP 654
Fly 655 TSQGVGIAAAAAGPMTAKTSTLTSCNQSHPLCGTANESPSTPEPRSRQPTTPQQQPHQQAHQQQQ 719
Fly 720 QQQQLSSIANPMQKVNKRKETLEAKRERKAAKTLAIITGAFVVCWLPFFVMALTMPLCAACQISD 784
Fly 785 SVASLFLWLGYFNSTLNPVIYTIFSPEFRQAFKRILFGGH 824 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| 5-HT1A | NP_001356890.1 | 7tmA_5-HT1A_invertebrates | 227..>413 | CDD:320454 | 86/191 (45%) |
| TM helix 1 | 228..254 | CDD:320454 | 8/25 (32%) | ||
| TM helix 2 | 261..287 | CDD:320454 | 15/25 (60%) | ||
| TM helix 3 | 299..329 | CDD:320454 | 19/29 (66%) | ||
| TM helix 4 | 340..362 | CDD:320454 | 8/22 (36%) | ||
| TM helix 5 | 383..412 | CDD:320454 | 16/28 (57%) | ||
| 7tm_GPCRs | <743..816 | CDD:355774 | 33/72 (46%) | ||
| TM helix 6 | 747..772 | CDD:341315 | 11/24 (46%) | ||
| TM helix 7 | 784..809 | CDD:341315 | 14/24 (58%) | ||
| HTR5A | NP_076917.1 | 7tmA_5-HT5 | 41..349 | CDD:320451 | 139/594 (23%) |
| TM helix 1 | 42..68 | CDD:320451 | 8/25 (32%) | ||
| TM helix 2 | 75..101 | CDD:320451 | 15/25 (60%) | ||
| TM helix 3 | 114..144 | CDD:320451 | 19/29 (66%) | ||
| TM helix 4 | 156..177 | CDD:320451 | 8/23 (35%) | ||
| TM helix 5 | 197..226 | CDD:320451 | 16/28 (57%) | ||
| TM helix 6 | 278..308 | CDD:320451 | 14/55 (25%) | ||
| TM helix 7 | 317..342 | CDD:320451 | 14/24 (58%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 1 | 1.100 | - | - | O | PTHR24247 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 2.010 | |||||