Protein Alignment 5-HT1A and or93a1

DIOPT Version :10

• Sequence 1: NP_001356890.1
• Gene: 5-HT1A / 37196
• FlyBaseID: FBgn0004168
• Length: 846
• Species: Drosophila melanogaster
• Sequence 2: XP_002665989.2
• Gene: or93a1 / 100331132
• ZFINID: ZDB-GENE-070806-34
• Length: 320
• Species: Danio rerio
• Alignment Length: 279
• Identity: 56/279 - (20%)
• Similarity: 101/279 - (36%)
• Gaps: 80/279 - (28%)

  Fly   209 NVTTSKVAED------DFTQLLRMAVTSVLL---GLMILVTIIGNVF-------VIAAIILERNL 257
            |||.|.:.:.      |...:|.::...:.|   |:||.......||       :...::....|
Zfish     5 NVTNSNITQTITPVDRDLKTILSVSSCVIFLYVNGVMIFTLRKKPVFQETSRYILFGHMLWVDTL 69

  Fly   258 QNVANYLVASLAVADLFV---ACLVMPLG--AVYEISQGWILGPELCDIWTSCDVLCCTASILHL 317
            ..|.:.::.:.||...||   .||::.:.  |:|::                        |.|:|
Zfish    70 NLVMSVVLFACAVFRPFVMKIVCLILLVAATALYQV------------------------STLNL 110

  Fly   318 VAIAVDRYWAVT-NIDYIHSRTSNRVFMMIFCVWTAAVIVSLAPQFGWKDPD------------- 368
            ..::::||.|:. .:.:....|..|..|.|..:|..:.|.||:....:...|
Zfish   111 ALMSLERYVAICFPLRHAEITTYGRTNMAIGVIWMISWIQSLSEIVIFYSIDTTNIAVNLFCSRT 175

  Fly   369 YLQRIEQQKCMVSQDVSYQVFATCCTFYVPLLVILALYWKIYQTARKRIHRRRPRPVDAAVNNNQ 433
            .|.|::..|   :.||::    ||..|.....:|:..|..|...|:             ..:.::
Zfish   176 TLFRLQIYK---NLDVAF----TCVYFVSVCFIIIFTYASIAAVAK-------------TASGDK 220

  Fly   434 PDGGAATDT-KLHRLRLRL 451
            .....||.| .||.::|.|
Zfish   221 ASAKKATKTVLLHLIQLGL 239

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
5-HT1A	NP_001356890.1	7tmA_5-HT1A_invertebrates	227..>413	CDD:320454	42/214 (20%)
		TM helix 1	228..254	CDD:320454	6/35 (17%)
		TM helix 2	261..287	CDD:320454	7/30 (23%)
		TM helix 3	299..329	CDD:320454	6/29 (21%)
		TM helix 4	340..362	CDD:320454	7/21 (33%)
		TM helix 5	383..412	CDD:320454	8/28 (29%)
		7tm_GPCRs	<743..816	CDD:475119
		TM helix 6	750..772	CDD:410628
		TM helix 7	784..809	CDD:410628
or93a1	XP_002665989.2	None