Protein Alignment Gpxl and GPX8

DIOPT Version :10

• Sequence 1: NP_611393.2
• Gene: Gpxl / 37194
• FlyBaseID: FBgn0034415
• Length: 193
• Species: Drosophila melanogaster
• Sequence 2: XP_006714694.1
• Gene: GPX8 / 493869
• HGNCID: 33100
• Length: 210
• Species: Homo sapiens
• Alignment Length: 182
• Identity: 59/182 - (32%)
• Similarity: 98/182 - (53%)
• Gaps: 6/182 - (3%)

  Fly    14 AVALVVVLQTRSRLQQDLQDMRWRL-TIHALTVRDTFGNPVQLDTFAG-HVLLIVNIASKCGLTL 76
            ||.|.:||.|.:.....|:.::.:: :.:|..|:|..|..|.|:.:.| .|.|:||:||.|.||.
Human    20 AVLLSIVLCTVTLFLLQLKFLKPKINSFYAFEVKDAKGRTVSLEKYKGKEVSLVVNVASDCQLTD 84

  Fly    77 SQYNGLRYLLEEYEDQGLRILNFPCNQFGGQMPESDGQEMLDHLRREGANIGHLFAKIDVKGAQA 141
            ..|.||:.|.:|:......:|.|||||||...|. ..:|:....|:.......:|.||.:.|::.
Human    85 RNYLGLKELHKEFGPSHFSVLAFPCNQFGESEPR-PSKEVESFARKNYGVTFPIFHKIKILGSEG 148

  Fly   142 DPLYK-LLTRHQHDIEWNFVKFLVDRKGNIHKRYGAELEPV-ALTDDIELLL 191
            :|.:: |:...:.:..|||.|:||:.:|.:.|.:..| ||: .:..||..|:
Human   149 EPAFRFLVDSSKKEPRWNFWKYLVNPEGQVVKFWKPE-EPIEVIRPDIAALV 199

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gpxl	NP_611393.2	GSH_Peroxidase	39..187	CDD:238207	49/150 (33%)
GPX8	XP_006714694.1	gpx7	46..199	CDD:131592	51/154 (33%)