| Sequence 1: | NP_001137708.2 | Gene: | 5-HT1B / 37191 | FlyBaseID: | FBgn0263116 | Length: | 629 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001356890.1 | Gene: | 5-HT1A / 37196 | FlyBaseID: | FBgn0004168 | Length: | 846 | Species: | Drosophila melanogaster |
| Alignment Length: | 727 | Identity: | 335/727 - (46%) |
|---|---|---|---|
| Similarity: | 399/727 - (54%) | Gaps: | 191/727 - (26%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 23 IELPAILLNESLFIELNGNLTQLVDTTSNLSQIVWNRS-----INGNG--NSNTFDLVDDEQERA 80
Fly 81 AVEFWLLVKMIAMAVVLGLMILVTIIGNVFVIAAIILERNLQNVANYLVASLAVADLFVACLVMP 145
Fly 146 LGAVYEISNGWILGPELCDIWTSCDVLCCTASILHLVAIAADRYWTVTNIDYNNLRTPRRVFLMI 210
Fly 211 FCVWFAALIVSLAPQFGWKDPDYMKRIEEQHCMVSQDVGYQIFATCCTFYVPLLVILFLYWKIYI 275
Fly 276 IARKRIQRRAQKSFNVTLTETDCD-SAVRELKKERSKRRAER---KRLEAGERTPVDGDGTGGQL 336
Fly 337 QRRTRKRMRICFGRNTNTANVVAGSEGAVARSMAAIAVDFASLAITREETEFSTSNYDNKSHAGT 401
Fly 402 ELTTVSSDADDYRTSNANEIITLSQQVAHATQH----HLIASHLNAITPLAQSIAMG-------- 454
Fly 455 -----------GVGCLTTTTPSEKALSGAGT-----------------------------VAGAV 479
Fly 480 AGGSGSGSGEEGAGT----------EGKNAGVGLGGV---------------------------- 506
Fly 507 -------------------------------LASIANPHQKLAKRRQLLEAKRERKAAQTLAIIT 540
Fly 541 GAFVICWLPFFVMALTMSLCKECEIHTAVASLFLWLGYFNSTLNPVIYTIFNPEFRRAFKRILFG 605
Fly 606 RKAAARARSAKI 617 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| 5-HT1B | NP_001137708.2 | 7tm_1 | 107..>288 | CDD:278431 | 157/180 (87%) |
| 5-HT1A | NP_001356890.1 | 7tmA_5-HT1A_invertebrates | 227..>413 | CDD:320454 | 161/185 (87%) |
| TM helix 1 | 228..254 | CDD:320454 | 21/25 (84%) | ||
| TM helix 2 | 261..287 | CDD:320454 | 25/25 (100%) | ||
| TM helix 3 | 299..329 | CDD:320454 | 27/29 (93%) | ||
| TM helix 4 | 340..362 | CDD:320454 | 17/21 (81%) | ||
| TM helix 5 | 383..412 | CDD:320454 | 25/28 (89%) | ||
| 7tm_GPCRs | <743..816 | CDD:355774 | 61/72 (85%) | ||
| TM helix 6 | 747..772 | CDD:341315 | 22/24 (92%) | ||
| TM helix 7 | 784..809 | CDD:341315 | 22/24 (92%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C45470085 | |
| Domainoid | 1 | 1.000 | 279 | 1.000 | Domainoid score | I1659 |
| eggNOG | 1 | 0.900 | - | - | E33208_3BCYC | |
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 305 | 1.000 | Inparanoid score | I2621 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D24048at7147 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0002041 | |
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 1 | 0.900 | - | - | OOG6_104614 | |
| Panther | 1 | 1.100 | - | - | P | PTHR24247 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| 9 | 8.800 | |||||