Protein Alignment 5-HT1B and htr5ab

DIOPT Version :9

• Sequence 1: NP_001137708.2
• Gene: 5-HT1B / 37191
• FlyBaseID: FBgn0263116
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_001007122.1
• Gene: htr5ab / 368475
• ZFINID: ZDB-GENE-030616-574
• Length: 346
• Species: Danio rerio
• Alignment Length: 515
• Identity: 139/515 - (26%)
• Similarity: 200/515 - (38%)
• Gaps: 208/515 - (40%)

  Fly    96 VLGLMILVTIIGNVFVIAAIILERNLQNVANYLVASLAVADLFVACLVMPLGAVYEI-SNGWILG 159
            :|.::::.|.:.|:.|:..|:..|....|.:.||||:|::|:.||.|||||..|.|: ...||||
Zfish    36 LLAMLVVATFVWNLLVLVTILRVRTFHRVPHNLVASMAISDVMVAGLVMPLSLVRELYGRRWILG 100

  Fly   160 PELCDIWTSCDVLCCTASILHLVAIAADRYWTVT-NIDYNNLRTPRRVF-LMIFCVWFAALIVSL 222
            ..||.:|.|||||||||||.::.|||.||||::| :::| .|:|.:|:. :||...|..:.::||
Zfish   101 RALCQVWISCDVLCCTASIWNVTAIALDRYWSITRHLEY-TLKTRKRISNVMIGLTWLLSSVISL 164

  Fly   223 APQFGWKDPDYMKRIEEQHCMVSQDVGYQIFATCCTFYVPLLVILFLYWKIYIIARKRIQRRAQK 287
            :|.|||.: .|.:  :...|.|||:..|.:|:|...||:||.|:||:|||||..|:.||.
Zfish   165 SPLFGWGE-TYSE--DSLACQVSQEPSYTVFSTFGAFYLPLCVVLFVYWKIYKAAKFRIG----- 221

  Fly   288 SFNVTLTETDCDSAVRELKKERSKRRAERKRLEAGERTPVDGDGTGGQLQRRTRKRMRICFGRNT 352
                                                                         .|.|
Zfish   222 -------------------------------------------------------------SRKT 225

  Fly   353 NTANVVAGSEGAVARSMAAIAVDFASLAITREETEFSTSNYDNKSHAGTELTTVSSDADDYRTSN 417
            ||
Zfish   226 NT--------------------------------------------------------------- 227

  Fly   418 ANEIITLSQQVAHATQHHLIASHLNAITPLAQSIAMGGVGCLTTTTPSEKALSGAGTVAGAVAGG 482
                                      |||:|:.|.:         ..:|:....|.||..|....
Zfish   228 --------------------------ITPMAEVIEV---------KEAERQPQMAFTVRHATVSF 257

  Fly   483 SGSGSGEEGAGTEGKNAGVGLGGVLASIANPHQKLAKRRQLLEAKRERKAAQTLAIITGAFVICW 547
            ...|                                   :....::||:||..:.|:.|.||:||
Zfish   258 QTDG-----------------------------------ETWREQKERRAALMVGILIGVFVLCW 287

  Fly   548 LPFFVMALTMSLCKECEIHTAVASLFLWLGYFNSTLNPVIYTIFNPEFRRAFKRILFGRK 607
            :|||:..|.:.|| .|:|.....|:||||||.||..||:|||.||..:..|| |.||.|:
Zfish   288 IPFFLAELIIPLC-SCDIPPVWKSVFLWLGYSNSFFNPLIYTAFNKNYNNAF-RNLFSRQ 345

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
5-HT1B	NP_001137708.2	7tm_1	107..>288	CDD:278431	82/183 (45%)
htr5ab	NP_001007122.1	7tm_1	47..327	CDD:278431	126/483 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24247
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X5850
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.010