Protein Alignment 5-HT1B and Htr7

DIOPT Version :9

• Sequence 1: NP_001137708.2
• Gene: 5-HT1B / 37191
• FlyBaseID: FBgn0263116
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_001334371.1
• Gene: Htr7 / 15566
• MGIID: 99841
• Length: 470
• Species: Mus musculus
• Alignment Length: 534
• Identity: 127/534 - (23%)
• Similarity: 194/534 - (36%)
• Gaps: 211/534 - (39%)

  Fly    88 VKMIAMAVVLGLMILVTIIGNVFVIAAIILERNLQNVANYLVASLAVADLFVACLVMPLGAVYEI 152
            |:.:.:..:|.|:.|:||.||..|:.::...:.|:..:|||:.|||:|||.||..|||..:|.::
Mouse    82 VEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSVTDL 146

  Fly   153 SNG-WILGPELCDIWTSCDVLCCTASILHLVAIAADRYWTVTN-IDYNNLRTPRRVFLMIFCVWF 215
            ..| ||.|...|:::.:.||:||||||:.|..|:.|||..:|. :.|...:..:.:..||..||.
Mouse   147 IGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWL 211

  Fly   216 AALIVSLAPQFGWKDPDYMKRIEEQHCMVSQDVGYQIFATCCTFYVPLLVILFLYWKIYIIARKR 280
            .:..::|.|.|||.    ....:::.|::|||.||.|::|...||:|:.|:||:|::||..|||
Mouse   212 LSASITLPPLFGWA----QNVNDDKVCLISQDFGYTIYSTAVAFYIPMSVMLFMYYQIYKAARK- 271

  Fly   281 IQRRAQKSFNVTLTETDCDSAVRELKKERSKRRAERKRLEAGERTPVDGDGTGGQLQRRTRKRMR 345
                               ||.:.
Mouse   272 -------------------SAAKH----------------------------------------- 276

  Fly   346 ICFGRNTNTANVVAGSEGAVARSMAAIAVDFASLAITREETEFSTSNYDNKSHAGTELTTVSSDA 410
                                         .|:.....:.|:..|
Mouse   277 -----------------------------KFSGFPRVQPESVIS--------------------- 291

  Fly   411 DDYRTSNANEIITLSQQVAHATQHHLIASHLNAITPLAQSIAMGGVGCLTTTTPSEKALSGAGTV 475
                   .|.::.|.::|........:..|
Mouse   292 -------LNGVVKLQKEVEECANLSRLLKH----------------------------------- 314

  Fly   476 AGAVAGGSGSGSGEEGAGTEGKNAGVGLGGVLASIANPHQKLAKRRQLLEAKRERKAAQTLAIIT 540
                               |.||..:                        .|||:|||.||.||.
Mouse   315 -------------------ERKNISI------------------------FKREQKAATTLGIIV 336

  Fly   541 GAFVICWLPFFVMALTMS-LC-KECE-IHTAVASLFLWLGYFNSTLNPVIYTIFNPEFRRAFKRI 602
            |||.:||||||:::.... :| ..|. |...|....|||||.||.:||.||..||.:.|..::.:
Mouse   337 GAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTCLWLGYANSLINPFIYAFFNRDLRTTYRSL 401

  Fly   603 L------FGRKAAA 610
            |      ..||.:|
Mouse   402 LQCQYRNINRKLSA 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
5-HT1B	NP_001137708.2	7tm_1	107..>288	CDD:278431	68/182 (37%)
Htr7	NP_001334371.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3253
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030