Protein Alignment 5-HT1B and Htr5b

DIOPT Version :9

• Sequence 1: NP_001137708.2
• Gene: 5-HT1B / 37191
• FlyBaseID: FBgn0263116
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_034613.2
• Gene: Htr5b / 15564
• MGIID: 96284
• Length: 370
• Species: Mus musculus
• Alignment Length: 516
• Identity: 140/516 - (27%)
• Similarity: 189/516 - (36%)
• Gaps: 207/516 - (40%)

  Fly    91 IAMAVVLGLMILVTIIGNVFVIAAIILERNLQNVANYLVASLAVADLFVACLVMPLGAVYEISNG 155
            :.:..:|.|:|:.|.:.|:.|:..|:..|....|.:.||||.||:|:.||.|||||..|.|:|.|
Mouse    53 VLVVTLLVLLIVATFLWNLLVLVTILRVRAFHRVPHNLVASTAVSDVLVAALVMPLSLVSELSVG 117

  Fly   156 --WILGPELCDIWTSCDVLCCTASILHLVAIAADRYWTVTNIDYNNLRTPRRV-FLMIFCVWFAA 217
              |.||..||.:|.|.|||||||||.::.|||.|||||:|......|||..|. .|||...|..:
Mouse   118 RRWQLGRSLCHVWISFDVLCCTASIWNVAAIALDRYWTITRHLQYTLRTRSRASALMIAITWALS 182

  Fly   218 LIVSLAP-QFGWKDPDYMKRIEEQHCMVSQDVGYQIFATCCTFYVPLLVILFLYWKIYIIARKRI 281
            .:::||| .|||.:. |..|:  |.|.|||:..|.:|:||..||:||.|:||:|||||..|:.|.
Mouse   183 ALIALAPLLFGWGEA-YDARL--QRCQVSQEPSYAVFSTCGAFYLPLAVVLFVYWKIYKAAKFRF 244

  Fly   282 QRRAQKSFNVTLTETDCDSAVRELKKERSKRRAERKRLEAGERTPVDGDGTGGQLQRRTRKRMRI 346
            .||.:....:..| |....|..|.:...:.||
Mouse   245 GRRRRAVVPLPAT-TQAKEAPPESEMVFTARR--------------------------------- 275

  Fly   347 CFGRNTNTANVVAGSEGAVARSMAAIAVDFASLAITREETEFSTSNYDNKSHAGTELTTVSSDAD 411
                                                |....|.||                  .|
Mouse   276 ------------------------------------RATVTFQTS------------------GD 286

  Fly   412 DYRTSNANEIITLSQQVAHATQHHLIASHLNAITPLAQSIAMGGVGCLTTTTPSEKALSGAGTVA 476
            .:|
Mouse   287 SWR-------------------------------------------------------------- 289

  Fly   477 GAVAGGSGSGSGEEGAGTEGKNAGVGLGGVLASIANPHQKLAKRRQLLEAKRERKAAQTLAIITG 541
                                                             .::|::||..:.|:.|
Mouse   290 -------------------------------------------------EQKEKRAAMMVGILIG 305

  Fly   542 AFVICWLPFFVMALTMSLCKECEIHTAVASLFLWLGYFNSTLNPVIYTIFNPEFRRAFKRI 602
            .||:||:|||:..|...|| .|.:.....|:||||||.||..||:|||.||..:..|||.:
Mouse   306 VFVLCWIPFFLTELISPLC-ACSLPPIWKSIFLWLGYSNSFFNPLIYTAFNKNYNNAFKSL 365

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
5-HT1B	NP_001137708.2	7tm_1	107..>288	CDD:278431	89/184 (48%)
Htr5b	NP_034613.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..36
		7tm_1	69..351	CDD:278431	128/484 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24247
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010