Protein Alignment 5-HT1B and Drd4

DIOPT Version :9

• Sequence 1: NP_001137708.2
• Gene: 5-HT1B / 37191
• FlyBaseID: FBgn0263116
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_031904.1
• Gene: Drd4 / 13491
• MGIID: 94926
• Length: 387
• Species: Mus musculus
• Alignment Length: 520
• Identity: 138/520 - (26%)
• Similarity: 204/520 - (39%)
• Gaps: 176/520 - (33%)

  Fly    92 AMAVVLGLMIL-VTIIGNVFVIAAIILERNLQNVANYLVASLAVADLFVACLVMPLGAVYEISNG 155
            |.|:|.|:::: :.:.||..|..::..||.||...||.:.|||.|||.:|.||:||....|:..|
Mouse    32 AAALVGGVLLIGLVLAGNSLVCVSVASERTLQTPTNYFIVSLAAADLLLAVLVLPLFVYSEVQGG 96

  Fly   156 -WILGPELCDIWTSCDVLCCTASILHLVAIAADRYWTVT-NIDYNNLRTPRRVFLMIFCVWFAAL 218
             |:|.|.|||...:.||:.|||||.:|.||:.||:..|| .:.||  :..:...|:|...|..:.
Mouse    97 VWLLSPRLCDTLMAMDVMLCTASIFNLCAISVDRFVAVTVPLRYN--QQGQCQLLLIAATWLLSA 159

  Fly   219 IVSLAPQFGWKD-PDYMKRIEEQHCMVSQDVGYQIFATCCTFYVPLLVILFLYWKIYIIARKRIQ 282
            .|:.....|..| |.   |.....|:.::|  |.::::.|:|::|..::|.|||..:     |..
Mouse   160 AVASPVVCGLNDVPG---RDPAVCCLENRD--YVVYSSVCSFFLPCPLMLLLYWATF-----RGL 214

  Fly   283 RRAQKSFNVTLTETDCDSAVRELK-KERSKRRAERKRLEAGERTPVDGDGTGGQLQRRTRKRMRI 346
            ||.:              |.|..| ..|:.||      .:|...|| .|.|.|..
Mouse   215 RRWE--------------AARHTKLHSRAPRR------PSGPGPPV-SDPTQGPF---------- 248

  Fly   347 CFGRNTNTANVVAGSEGAVARSMAAIAVDFASLAITREETEFSTSNYDNKSHAGTELTTVSSDAD 411
                                                          :.:.......|.|..||:.
Mouse   249 ----------------------------------------------FPDCPPPLPSLRTSPSDSS 267

  Fly   412 DYRTSNANEIITLSQQVAHATQHHLIASHLNAITPLAQSIAMGGVGCLTTTTPSEKALSGAGTVA 476
            ...:.       |||:                  |.:.       |||...
Mouse   268 RPESE-------LSQR------------------PCSP-------GCLLAD-------------- 286

  Fly   477 GAVAGGSGSGSGEEGAGTEGKNAGVGLGGVLASIANPHQKLAKRRQLLEAK---RERKAAQTLAI 538
                                           |::..|.:..::||:  .||   |||||.:.|.:
Mouse   287 -------------------------------AALPQPPEPSSRRRR--GAKITGRERKAMRVLPV 318

  Fly   539 ITGAFVICWLPFFVMALTMSLCKECEIHTAVASLFLWLGYFNSTLNPVIYTIFNPEFRRAFKRIL 603
            :.|||::||.||||:.:|.:||..|.:...:.|...||||.||.|||:||||||.|||..|::.|
Mouse   319 VVGAFLVCWTPFFVVHITRALCPACFVSPRLVSAVTWLGYVNSALNPIIYTIFNAEFRSVFRKTL 383

  Fly   604  603
            Mouse   384  383

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
5-HT1B	NP_001137708.2	7tm_1	107..>288	CDD:278431	65/183 (36%)
Drd4	NP_031904.1	7tm_1	48..368	CDD:278431	123/487 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	224..247		9/29 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	287..306		6/20 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910