Protein Alignment 5-HT1B and htr1e

DIOPT Version :9

• Sequence 1: NP_001137708.2
• Gene: 5-HT1B / 37191
• FlyBaseID: FBgn0263116
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: XP_002933964.1
• Gene: htr1e / 100380026
• XenbaseID: XB-GENE-965113
• Length: 362
• Species: Xenopus tropicalis
• Alignment Length: 537
• Identity: 140/537 - (26%)
• Similarity: 206/537 - (38%)
• Gaps: 221/537 - (41%)

  Fly    89 KMIAMAVVLGLMILVTIIGNVFVIAAIILERNLQNVANYLVASLAVADLFVACLVMPLGAVYEIS 153
            ||: :::.|.::.::|.:.|..||.||...:.|...||||:.||||.|..||.|||||...|.:.
 Frog    19 KML-ISLTLAIITILTTVLNSAVILAICTTKKLHQPANYLICSLAVTDFLVAILVMPLSITYIVM 82

  Fly   154 NGWILGPELCDIWTSCDVLCCTASILHLVAIAADRYWTVTN-IDYNNLRTPRRVFLMIFCVWFAA 217
            :.|.||..:|:||.|.|:.|||.|||||..||.||||.:|: |:|...||.:|..:||..||..:
 Frog    83 DTWTLGYVICEIWLSVDMTCCTCSILHLCVIALDRYWAITDAIEYARKRTVKRAGIMILTVWTIS 147

  Fly   218 LIVSLAPQFGWKDPDYMKRIEEQH-------CMVSQD-VGYQIFATCCTFYVPLLVILFLYWKIY 274
            :.:|:.|.| |::         .|       |::..| :.|.|::||..||:||.:||.||::||
 Frog   148 VFISIPPLF-WRN---------HHNINIPSKCIIQHDHLIYTIYSTCGAFYIPLTLILILYYRIY 202

  Fly   275 IIARKRIQRR------------AQKSF-NVTLTETDCDSAVRELKKERSKRRAERKRLEAGERTP 326
            ..|:...|:|            :|.|| :..||:|.|.|     :...|....|.:::.|..|||
 Frog   203 HAAKNLYQKRGSSRHLSNRSNDSQNSFAHCKLTQTFCVS-----EFSTSDPTTEFEKMNASVRTP 262

  Fly   327 VDGDGTGGQLQRRTRKRMRICFGRNTNTANVVAGSEGAVARSMAAIAVDFASLAITREETEFSTS 391
                                                                             
 Frog   263 ----------------------------------------------------------------- 262

  Fly   392 NYDNKSHAGTELTTVSSDADDYRTSNANEIITLSQQVAHATQHHLIASHLNAITPLAQSIAMGGV 456
            .|||             |.|.:
 Frog   263 PYDN-------------DIDIF------------------------------------------- 271

  Fly   457 GCLTTTTPSEKALSGAGTVAGAVAGGSGSGSGEEGAGTEGKNAGVGLGGVLASIANPHQKLAKRR 521
                                                                         ..|:
 Frog   272 -------------------------------------------------------------GDRQ 275

  Fly   522 QLLEAKRERKAAQTLAIITGAFVICWLPFFVMALTMSLCKECEIHTAVASLFLWLGYFNSTLNPV 586
            |.:.:.||||||:.|.:|.|||::.|||||:..|.:.: :.|.:...||....||||.||.:||:
 Frog   276 QQISSSRERKAARILGLILGAFILSWLPFFIKELVVGI-QLCTVSPEVADFLTWLGYVNSLVNPL 339

  Fly   587 IYTIFNPEFRRAFKRIL 603
            :||.||.:|:.|||:::
 Frog   340 LYTSFNDDFKLAFKKLI 356

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
5-HT1B	NP_001137708.2	7tm_1	107..>288	CDD:278431	80/201 (40%)
htr1e	XP_002933964.1	7tmA_5-HT1E	20..352	CDD:320457	136/530 (26%)
		TM helix 1	21..47	CDD:320457	7/26 (27%)
		TM helix 2	54..80	CDD:320457	16/25 (64%)
		TM helix 3	92..122	CDD:320457	19/29 (66%)
		TM helix 4	134..156	CDD:320457	7/21 (33%)
		TM helix 5	175..204	CDD:320457	14/28 (50%)
		TM helix 6	281..311	CDD:320457	17/29 (59%)
		TM helix 7	320..345	CDD:320457	12/24 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D310620at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920