Protein Alignment 5-HT1B and htr5aa

DIOPT Version :9

• Sequence 1: NP_001137708.2
• Gene: 5-HT1B / 37191
• FlyBaseID: FBgn0263116
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_001119882.2
• Gene: htr5aa / 100038775
• ZFINID: ZDB-GENE-060531-129
• Length: 345
• Species: Danio rerio
• Alignment Length: 560
• Identity: 151/560 - (26%)
• Similarity: 220/560 - (39%)
• Gaps: 220/560 - (39%)

  Fly    52 LSQIVWNRSINGNGNSNTFDLVDDEQERAAVEFWLLVKMIAMAVVLGLMILVTIIGNVFVIAAII 116
            :|.:..|.|.| |.:|:..::...:...:.:.|.|          |.::::.|...|:.|:..|:
Zfish     1 MSDVSQNSSFN-NQSSDYGNVYRPQTVFSVLTFTL----------LAMLVVATFFWNMLVLVTIL 54

  Fly   117 LERNLQNVANYLVASLAVADLFVACLVMPLGAVYEISNG--WILGPELCDIWTSCDVLCCTASIL 179
            ..|....|.:.||||:|::|:.||.|||||..|:|: ||  |.||..||.:|.|.|||||||||.
Zfish    55 RVRTFHRVPHNLVASMAISDVMVAALVMPLSLVHEL-NGRRWKLGRVLCQVWISFDVLCCTASIW 118

  Fly   180 HLVAIAADRYWTVT-NIDYNNLRTPRRVF-LMIFCVWFAALIVSLAPQFGWKDPDYMKRIEEQHC 242
            ::.|||.||||::| :::| .|:|.:::. :||...|..:.::||:|.|||.: .|.:  |...|
Zfish   119 NVTAIALDRYWSITRHLEY-TLKTRKKISNVMIGLTWLLSSVISLSPLFGWGE-TYSE--ENMEC 179

  Fly   243 MVSQDVGYQIFATCCTFYVPLLVILFLYWKIYIIARKRIQRRAQKSFNVTLTETDCDSAVRELKK 307
            .|||:..|.||:|...||:||.|:||:|||||..|:.||
Zfish   180 QVSQEPSYTIFSTFGAFYLPLCVVLFVYWKIYKAAKFRI-------------------------- 218

  Fly   308 ERSKRRAERKRLEAGERTPVDGDGTGGQLQRRTRKRMRICFGRNTNTANVVAGSEGAVARSMAAI 372
             .|||        ....|||   ...|:::..:|::.::.|
Zfish   219 -GSKR--------TNTITPV---AEAGEVKEASRQQPQMVF------------------------ 247

  Fly   373 AVDFASLAITREETEFSTSNYDNKSHAGTELTTVSSDADDYRTSNANEIITLSQQVAHATQHHLI 437
                                                                  .|.|||
Zfish   248 ------------------------------------------------------TVRHAT----- 253

  Fly   438 ASHLNAITPLAQSIAMGGVGCLTTTTPSEKALSGAGTVAGAVAGGSGSGSGEEGAGTEGKNAGVG 502
                                 :|..|.||
Zfish   254 ---------------------VTFQTDSE------------------------------------ 261

  Fly   503 LGGVLASIANPHQKLAKRRQLLEAKRERKAAQTLAIITGAFVICWLPFFVMALTMSLCKECEIHT 567
                           ..|.|     :|::||..:.|:.|.||:||:|||:..|...|| .|.|..
Zfish   262 ---------------TWREQ-----KEKRAALMVGILIGVFVLCWIPFFLTELITPLC-SCHIPP 305

  Fly   568 AVASLFLWLGYFNSTLNPVIYTIFNPEFRRAFKRILFGRK 607
            ...|:||||||.||..||:|||.||..:..|| |.||.|:
Zfish   306 IWKSVFLWLGYSNSFFNPLIYTAFNKNYNNAF-RNLFSRQ 344

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
5-HT1B	NP_001137708.2	7tm_1	107..>288	CDD:278431	83/184 (45%)
htr5aa	NP_001119882.2	7tm_1	45..326	CDD:278431	130/484 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24247
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X5850
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	4.010