DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tn and AT1G56500

DIOPT Version :9

Sequence 1:	NP_001137707.1	Gene:	tn / 37190	FlyBaseID:	FBgn0265356	Length:	1517	Species:	Drosophila melanogaster
Sequence 2:	NP_564718.2	Gene:	AT1G56500 / 842103	AraportID:	AT1G56500	Length:	1055	Species:	Arabidopsis thaliana

Alignment Length:	431	Identity:	92/431 - (21%)
Similarity:	151/431 - (35%)	Gaps:	142/431 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly  1194 LASSDDDGSKNGLGSPTSPTVAAAVAAAGITGAAGTIPKQVYLRKRQQLFQLGGRGSEPGSFT-- 1256
            :|....:|.:..|    ...||||:...|......:.|....|.|          .::|...|
plant   515 IAQIAGEGHRKDL----DDVVAAALTYYGGKNVLDSTPLPTRLEK----------DNDPRLATSP 565

  Fly  1257 --WPRGLAVGP-DNSIVVADSSNHRVQVFDSNGIFVKEF---GEYGNGEGEFDCLA-----GVAV 1310
              :|..||:.. :|.:.::||:::|:.|.|..|.|:.:.   ||.|..:|.|:..|     |:|.
plant   566 LKFPGKLAIDTLNNRLFISDSNHNRIIVTDLEGNFIVQIGSSGEEGFQDGSFEDAAFNRPQGLAY 630

  Fly  1311 N-RIGQYIIADRYNHRIQVLDPQGRFLRAFGSQGTADGKF-----------NYPW---------- 1353
            | :.....:||..||.::.:|.....::.....||....:           |.||
plant   631 NAKKNLLYVADTENHALREIDFVNERVQTLAGNGTKGSDYQGGRKGTKQLLNSPWDVCFEPVNEK 695

  Fly  1354 ----------------------------------GVTTDALGF--------------IYVCDKEN 1370
                                              |.|.....|              .|:.|.|:
plant   696 VYIAMAGQHQIWEYSVLDGITRVFSGNGYERNLNGSTPQTTSFAQPSGISLGPDLKEAYIADSES 760

  Fly  1371 HRVQV--FQSDGS--FVG----------KFG-SCGRG-EGQLEHPHYIAVSNTNRVIVSDSNNHR 1419
            ..::.  .|:.||  ..|          ||| :.|.| |..|:||..:..:|..::.::||.||:
plant   761 SSIRALDLQTGGSRLLAGGDPYFSENLFKFGDNDGVGAEVLLQHPLGVLCANDGQIYLTDSYNHK 825

  Fly  1420 IQIFDVNGKVLSTVGGEGS---DDG-----QFKFPRGVAVDDQGYIFVADSGNNRIQIFN----- 1471
            |:..|...|.:.|:.|.|.   .||     |...|.|:|:.:.|.:||||:.|:.|:..:
plant   826 IKKLDPVTKRVVTLAGTGKAGFKDGKVKGAQLSEPAGLAITENGRLFVADTNNSLIRYIDLNKGE 890

  Fly  1472 ----------------PDGSFLKTFGSWGSGDSEFKGLEGV 1496
                            |....||......|.|::...::.|
plant   891 DSEILTLELKGVQPPTPKAKSLKRLRKRASADTKIVKVDSV 931

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tn	NP_001137707.1	RING	9..54	CDD:238093
		zf-B_box	94..>122	CDD:279037
		iSH2_PI3K_IA_R	131..231	CDD:304922
		NHL_TRIM71_like	1234..1517	CDD:271324	83/391 (21%)
		YncE	1253..>1517	CDD:225926	80/372 (22%)
		NHL repeat	1258..1297	CDD:271324	13/42 (31%)
		WD40 repeat	1261..1304	CDD:293791	15/46 (33%)
		NHL repeat	1305..1344	CDD:271324	9/44 (20%)
		WD40 repeat	1345..1377	CDD:293791	9/102 (9%)
		NHL repeat	1352..1388	CDD:271324	15/108 (14%)
		NHL repeat	1396..1436	CDD:271324	12/39 (31%)
		WD40 repeat	1402..1439	CDD:293791	11/39 (28%)
		NHL repeat	1445..1475	CDD:271324	11/50 (22%)
		WD40 repeat	1446..1485	CDD:293791	13/59 (22%)
		NHL repeat	1491..1517	CDD:271324	1/6 (17%)
AT1G56500	NP_564718.2	PLN02919	1..1055	CDD:215497	92/431 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910