DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment tn and ftr56

DIOPT Version :9

Sequence 1:	NP_001137707.1	Gene:	tn / 37190	FlyBaseID:	FBgn0265356	Length:	1517	Species:	Drosophila melanogaster
Sequence 2:	XP_003200605.1	Gene:	ftr56 / 561680	ZFINID:	ZDB-GENE-030131-2801	Length:	561	Species:	Danio rerio

Alignment Length:	350	Identity:	69/350 - (19%)
Similarity:	136/350 - (38%)	Gaps:	74/350 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 EQFEQLLTCCVCLDRYRIPKLLPCQHSFCMEPCMEGLVDY-----VRRQVKCPECRAEHRIPYNG 61
            |||    :|.|||:..:.|..:||.||:||. |   :.||     .:|...||:||.    .::.
Zfish     9 EQF----SCPVCLELLKNPVAIPCGHSYCMS-C---ITDYWHHEDEKRVYSCPQCRQ----TFSP 61

  Fly    62 VQAFPTNVTLQRFLEL------HIEITGELPDPTSGQIMERCGVCSEKAY--LSHCAHCEKKICE 118
            ..|...|..|...:|.      |   |..:|   :|.....|..|:.:.:  :..|..|....|:
Zfish    62 RPALNKNTMLAEVVEQLKKTKHH---TAAVP---AGDGDVECDSCTGRKHKAIKSCLVCLNSYCQ 120

  Fly   119 DCKSAHMDIL---RREITRFNSQIRRSLHRLQDSLAII-------------------EKNTMSLQ 161
            :....|.::.   |..:.....:::..:.|..|.|..|                   :..|:|..
Zfish   121 NHLEQHENLFKGKRHNLIDATGRLQEMICRKHDKLLEIYCRTDQRCICMLCMVDEHKDHETVSTS 185

  Fly   162 TNAISVTEEIDEIYQRITKAIKDRSDQLKGEIDRYLAVELRNLTTLKENLDLEITNITSNCDTVD 226
            .......:::.||.::..:.|:.|..:|: |::..:.:..|:..|..::.:...:.:..   :::
Zfish   186 AERTEKQKQLGEIQRKFQQQIQKRERKLQ-ELNEAVKIHERSAQTAVKDSERVFSELIR---SIE 246

  Fly   227 KYMNETVEWDDCELMDTKEIFLKTVE-FLRHFEYENNDYSRRVRFLVSID-PNQLVMNLATFGDL 289
            :..:|..:.    :.|.::|.:...| .|:..:.|.:|...:...|..:. .:..:..:.:|..|
Zfish   247 RKRSEVTQM----IRDQEKITVGRAEGLLKQLQQEIDDLRGKNAKLEQLSHTHDHICFIQSFASL 307

  Fly   290 NIAPHS--TPS---------GGSVS 303
            .:.|.|  .||         |.|||
Zfish   308 PVPPASPDVPSITVSSYDDVGKSVS 332

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tn	NP_001137707.1	RING	9..54	CDD:238093	19/49 (39%)
		zf-B_box	94..>122	CDD:279037	5/29 (17%)
		iSH2_PI3K_IA_R	131..231	CDD:304922	14/118 (12%)
		NHL_TRIM71_like	1234..1517	CDD:271324
		YncE	1253..>1517	CDD:225926
		NHL repeat	1258..1297	CDD:271324
		WD40 repeat	1261..1304	CDD:293791
		NHL repeat	1305..1344	CDD:271324
		WD40 repeat	1345..1377	CDD:293791
		NHL repeat	1352..1388	CDD:271324
		NHL repeat	1396..1436	CDD:271324
		WD40 repeat	1402..1439	CDD:293791
		NHL repeat	1445..1475	CDD:271324
		WD40 repeat	1446..1485	CDD:293791
		NHL repeat	1491..1517	CDD:271324
ftr56	XP_003200605.1	zf-C3HC4_4	13..55	CDD:291880	17/45 (38%)
		zf-B_box	145..183	CDD:279037	5/37 (14%)
		DUF4200	190..290	CDD:290574	16/107 (15%)
		SPRY_PRY_SNTX	367..534	CDD:294002
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	0	0.000