DRSC/TRiP Functional Genomics Resources

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Protein Alignment tn and trim45

DIOPT Version :9

Sequence 1:NP_001137707.1 Gene:tn / 37190 FlyBaseID:FBgn0265356 Length:1517 Species:Drosophila melanogaster
Sequence 2:XP_686393.2 Gene:trim45 / 558117 ZFINID:ZDB-GENE-070912-389 Length:574 Species:Danio rerio


Alignment Length:319 Identity:69/319 - (21%)
Similarity:119/319 - (37%) Gaps:84/319 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly    10 CCVCLDRYRIPKLLPCQHSFCMEPCMEGLVDYVRRQVK------------------CPECRAEHR 56
            |.||...||.||:|||.|:||.: |:..|..:..|:|.                  ||:|.:|..
Zfish    27 CGVCNRMYREPKILPCLHTFCAD-CVRQLEPFSVRRVNGDRRSPGEDNSGSGSTILCPQCDSEVD 90

  Fly    57 IPYNGVQAFPT-NVTLQR-FLELHIEITGELPDPTS-GQIMERCGVC-------------SEKAY 105
            :|.:||....| ::.|.. |.|..:.....|.|..| ....:||.||             .:|..
Zfish    91 LPPSGVDGLTTDHLALDEVFTETLVVNNSVLCDLCSDSDAGKRCEVCCVNLCDFCSQAHRRQKRT 155

  Fly   106 LSH-------------------------------CAHCEKKICEDC-----KSAHMDILRREITR 134
            .||                               |..|:..:|.:|     :..|.......|:|
Zfish   156 SSHSIQTLQELKSQGRLTRPILCSLHPGQELRLFCEPCDLTVCLECAATFHREHHCSSTHEVISR 220

  Fly   135 FNSQIR----RSLH----RLQDSLAIIEKNTMSLQTNAISVTEEIDEIYQRITKAIKDRSDQLKG 191
            :..:||    |||.    ||::||..::.:..::|....::..||....:....|::.....|..
Zfish   221 YGDRIRDLLVRSLKPRLARLEESLRRVDTSQEAMQARTDTLAGEIRAFARAYASAVEAHCCSLLR 285

  Fly   192 EIDRYLAVELRN-LTTLKENLDLEITNITSNCDTVDKYMNETVEWDDCELMDTKEIFLK 249
            .:|. |..:.|| |...|..|...::::....:..::.:   :...|.|::..|.:.::
Zfish   286 SLDD-LRTQRRNQLQLQKAQLQQALSDVRGGVEFTERLL---MCGSDAEILTAKGVTMR 340

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
tnNP_001137707.1 RING 9..54 CDD:238093 20/61 (33%)
zf-B_box 94..>122 CDD:279037 11/76 (14%)
iSH2_PI3K_IA_R 131..231 CDD:304922 23/108 (21%)
NHL_TRIM71_like 1234..1517 CDD:271324
YncE 1253..>1517 CDD:225926
NHL repeat 1258..1297 CDD:271324
WD40 repeat 1261..1304 CDD:293791
NHL repeat 1305..1344 CDD:271324
WD40 repeat 1345..1377 CDD:293791
NHL repeat 1352..1388 CDD:271324
NHL repeat 1396..1436 CDD:271324
WD40 repeat 1402..1439 CDD:293791
NHL repeat 1445..1475 CDD:271324
WD40 repeat 1446..1485 CDD:293791
NHL repeat 1491..1517 CDD:271324
trim45XP_686393.2 zf-B_box 173..209 CDD:279037 4/35 (11%)
Filamin 390..487 CDD:279024
IG_FLMN 392..491 CDD:214720
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D489543at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.920

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