DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tn and F43G6.8

DIOPT Version :9

Sequence 1:	NP_001137707.1	Gene:	tn / 37190	FlyBaseID:	FBgn0265356	Length:	1517	Species:	Drosophila melanogaster
Sequence 2:	NP_496523.1	Gene:	F43G6.8 / 174815	WormBaseID:	WBGene00009660	Length:	263	Species:	Caenorhabditis elegans

Alignment Length:	81	Identity:	24/81 - (29%)
Similarity:	35/81 - (43%)	Gaps:	21/81 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 QFEQ---------LLTCCVCL------DRYRIPKLLPCQHSFCMEPCMEGLVDYVRRQVKCPECR 52
            ||||         ...|.:|.      |.| :|::|.|.|:.|.. |:|.|  .|...::||.||
Worm   183 QFEQQEVTGETPLWKLCEICAHQFSHSDEY-VPRVLVCGHTLCTS-CIEKL--DVGDGIRCPFCR 243

  Fly    53 AEHRIPYNGVQAFPTN 68
            ....:  ..::|.|.|
Worm   244 TWTNM--KRIEALPKN 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tn	NP_001137707.1	RING	9..54	CDD:238093	17/50 (34%)
		zf-B_box	94..>122	CDD:279037
		iSH2_PI3K_IA_R	131..231	CDD:304922
		NHL_TRIM71_like	1234..1517	CDD:271324
		YncE	1253..>1517	CDD:225926
		NHL repeat	1258..1297	CDD:271324
		WD40 repeat	1261..1304	CDD:293791
		NHL repeat	1305..1344	CDD:271324
		WD40 repeat	1345..1377	CDD:293791
		NHL repeat	1352..1388	CDD:271324
		NHL repeat	1396..1436	CDD:271324
		WD40 repeat	1402..1439	CDD:293791
		NHL repeat	1445..1475	CDD:271324
		WD40 repeat	1446..1485	CDD:293791
		NHL repeat	1491..1517	CDD:271324
F43G6.8	NP_496523.1	SMC_prok_B	<15..>188	CDD:274008	4/4 (100%)
F43G6.8	NP_496523.1	RING-HC_TRIM32_C-VII	198..243	CDD:319501	15/48 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D489543at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920