DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG18605 and Topors

DIOPT Version :9

Sequence 1:	NP_001188974.1	Gene:	CG18605 / 37189	FlyBaseID:	FBgn0034411	Length:	415	Species:	Drosophila melanogaster
Sequence 2:	NP_001102128.1	Gene:	Topors / 362501	RGDID:	1305270	Length:	1042	Species:	Rattus norvegicus

Alignment Length:	436	Identity:	92/436 - (21%)
Similarity:	169/436 - (38%)	Gaps:	90/436 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 MVQWRIYVYANSLYSLPDRETGDFRGWSPEYFRLNPFEVHRVMMWVNRDVSVLIRTRKADIFYLY 70
            ::.:|..:|...:......:.|.:|..|.|:||.||..:||::.|:.|:::||.....:.:..:.
  Rat   257 IINFRRTLYRAGVRVRSIEDGGRYRDISAEFFRRNPACLHRLVPWLKRELTVLFGAHGSLVNIVQ 321

  Fly    71 ETIKNLLPRLKLDSEEFRKPMIHFFGANTDLFIHELINFARSPYDTLMAYECSTQYRALLDFDNG 135
            ..|.:.:.|..|:|:.|...:..|....|:.||||.|:|||||:: :.|::....|      |..
  Rat   322 HIIMSNVTRYDLESQAFVSDLRPFLLNRTEHFIHEFISFARSPFN-MAAFDQHANY------DCP 379

  Fly   136 PTTSAKSRDREFLSTRLHSFVEFTRRINYDDCGGFEADLEL--------EDEDFGELDDMMMERY 192
            |::...||....:.|           |:.|:....|.|:.:        :||..|.......:.:
  Rat   380 PSSEEGSRSDSSVIT-----------ISPDEAEAQELDVNVSTIRQAPWDDETPGPSYSNSEQVH 433

  Fly   193 GGAPFLM----KMDGQLVT---ARIIPSSQANAPNQGQVNQQTQSQAQAQAQAQAQVQAQAQAQA 250
            .|...|:    ..|.:||:   |..|...|||    ..||..:.|.:. .......|:..|:...
  Rat   434 VGVSSLLNSSDSSDEELVSGGAASQIQGVQAN----DDVNNDSDSSSD-NCVIVGFVKPLAERTP 493

  Fly   251 Q-TQAQTQAQALAQAQAQAQVQAQPQAQVQQA-------AAQPAQLLLPQLTQAVIQTQQRAVHQ 307
            : .:..:.::.|...:....|:.|.|.|...:       |:.|..:|
  Rat   494 ELVELSSDSEELGSYEKMETVKTQEQEQSYSSGDSDASRASSPRSVL------------------ 540

  Fly   308 PQQSGQQSGPQHASSTAALATPLEDLELGFAIERSMFVGA---SNADQGGDFILPYGQVFRFANT 369
              ...:|.|..|..|...:.:..|:       :||..:..   |::.:|.....||....|....
  Rat   541 --GKDEQMGKSHCDSDTRINSKKEE-------KRSTSLSTPRDSSSTRGDRACSPYNHRHRKGGR 596

  Fly   370 NRAARPSNGNGSGSGVMNPPPAPPVPNNPRNASAHQGRRRRTQNQR 415
            :|::...:.:.||             ::.||...|.| ::|.:|:|
  Rat   597 SRSSDSRSQSRSG-------------HDQRNHRKHHG-KKRLKNKR 628

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID
CG18605	NP_001188974.1	None
Topors	NP_001102128.1	RING	103..146	CDD:238093
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166339567
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4430
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003652
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.830