| Sequence 1: | NP_001188974.1 | Gene: | CG18605 / 37189 | FlyBaseID: | FBgn0034411 | Length: | 415 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_598858.2 | Gene: | Topors / 106021 | MGIID: | 2146189 | Length: | 1033 | Species: | Mus musculus |
| Alignment Length: | 433 | Identity: | 89/433 - (20%) |
|---|---|---|---|
| Similarity: | 164/433 - (37%) | Gaps: | 83/433 - (19%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 6 MVQWRIYVYANSLYSLPDRETGDFRGWSPEYFRLNPFEVHRVMMWVNRDVSVLIRTRKADIFYLY 70
Fly 71 ETIKNLLPRLKLDSEEFRKPMIHFFGANTDLFIHELINFARSPYDTLMAYECSTQYRALLDFDNG 135
Fly 136 PTTSAKSRDREFLSTRLHSFVEFTRRINYDDCGGFEADLEL--------EDEDFGELDDMMMERY 192
Fly 193 GGAPFLM----KMDGQLVTARIIPSSQANAPNQGQVNQQTQSQAQAQAQAQAQVQAQAQAQAQ-T 252
Fly 253 QAQTQAQALAQAQAQAQVQAQPQAQVQQA-------AAQPAQLLLPQLTQAVIQTQQRAVHQPQQ 310
Fly 311 SGQQSGPQHASSTAALATPLEDLELGFAIERSMFVGA---SNADQGGDFILPYGQVFRFANTNRA 372
Fly 373 ARPSNGNGSGSGVMNPPPAPPVPNNPRNASAHQGRRRRTQNQR 415 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| CG18605 | NP_001188974.1 | None | |||
| Topors | NP_598858.2 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..36 | ||
| Required for DNA-binding. /evidence=ECO:0000250 | 52..376 | 34/119 (29%) | |||
| RING | 103..146 | CDD:238093 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 414..477 | 13/63 (21%) | |||
| Interaction with SUMO1. /evidence=ECO:0000250 | 438..654 | 41/234 (18%) | |||
| Sumoylation and localization to discrete nuclear foci. /evidence=ECO:0000250 | 438..574 | 26/164 (16%) | |||
| Interaction with TOP1. /evidence=ECO:0000250 | 457..879 | 37/215 (17%) | |||
| Interaction with p53/TP53. /evidence=ECO:0000250 | 457..731 | 37/215 (17%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 496..692 | 30/174 (17%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 713..934 | ||||
| Interaction with UBE2I. /evidence=ECO:0000250 | 851..914 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 970..1033 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C167835929 | |
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG4430 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 1 | 1.000 | - | - | FOG0003652 | |
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 0 | 0.000 | Not matched by this tool. | |||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 4 | 3.830 | |||||