DRSC/TRiP Functional Genomics Resources

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Protein Alignment Jheh3 and EPHX3

DIOPT Version :9

Sequence 1:NP_611387.1 Gene:Jheh3 / 37182 FlyBaseID:FBgn0034406 Length:468 Species:Drosophila melanogaster
Sequence 2:NP_001136358.1 Gene:EPHX3 / 79852 HGNCID:23760 Length:360 Species:Homo sapiens


Alignment Length:284 Identity:66/284 - (23%)
Similarity:106/284 - (37%) Gaps:75/284 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly   134 GLNIHYIHEKVSEEAKEKKHVYPLLL-LHGWPGS-------VREFFDFIPMLTKHSNITDYAFEV 190
            ||.:||:        ...:...||:| |||:|.:       :|||              ...|.|
Human    84 GLRLHYV--------SAGRGNGPLMLFLHGFPENWFSWRYQLREF--------------QSRFHV 126

  Fly   191 VAPSLVGYGWSDAATRPGFNAAEMATV-MRNLMLRLGHKKFFIQGGDWGSIIGSNLATLYPENVI 254
            ||..|.|||.|||.........::..| :::::|.||:.|..:...|||:::..:.:..||.   
Human   127 VAVDLRGYGPSDAPRDVDCYTIDLLLVDIKDVILGLGYSKCILVAHDWGALLAWHFSIYYPS--- 188

  Fly   255 GYHSNMCVLHTPLAILKGIYGSFFPEKYLP--SRFFVDHHFPVWE-KWL--ELLEESGYFHIQAT 314
                    |...:.::.|...|.:.:..|.  |:||..|:..::: .||  :||..|.:..::.|
Human   189 --------LVERMVVVSGAPMSVYQDYSLHHISQFFRSHYMFLFQLPWLPEKLLSMSDFQILKTT 245

  Fly   315 KPDTIGAALTSSPVGLASYILEKFQTCTNPGLKQDFGAIVTVFGLEAVLDNLMVYY--------L 371
                    ||....|:         .|..|   .:..|.:..|.....|...:.||        |
Human   246 --------LTHRKTGI---------PCLTP---SELEAFLYNFSQPGGLTGPLNYYRNLFRNFPL 290

  Fly   372 TNSATTAARFYLENVSKTYRDLQL 395
            .....|.....|.....||.:|.|
Human   291 EPQELTTPTLLLWGEKDTYLELGL 314

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Jheh3NP_611387.1 EHN 60..165 CDD:283978 10/31 (32%)
Abhydrolase 135..>251 CDD:304388 33/124 (27%)
EPHX3NP_001136358.1 MhpC 80..351 CDD:223669 66/284 (23%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R2361
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.940

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