DRSC/TRiP Functional Genomics Resources

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Protein Alignment Jheh3 and Ephx4

DIOPT Version :9

Sequence 1:NP_611387.1 Gene:Jheh3 / 37182 FlyBaseID:FBgn0034406 Length:468 Species:Drosophila melanogaster
Sequence 2:NP_001001804.2 Gene:Ephx4 / 384214 MGIID:2686228 Length:359 Species:Mus musculus


Alignment Length:350 Identity:81/350 - (23%)
Similarity:125/350 - (35%) Gaps:101/350 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly   134 GLNIHYIHEKVSEEAKEKKHVYPL-LLLHG-------WPGSVREFFDFIPMLTKHSNITDYAFEV 190
            ||..||:  ...|..|      || |||||       |...:|||              ...:.|
Mouse    78 GLRFHYV--AAGERGK------PLMLLLHGFPEFWYSWRHQLREF--------------KSEYRV 120

  Fly   191 VAPSLVGYGWSDA-ATRPGFNAAEMATVMRNLMLRLGHKKFFIQGGDWGSIIGSNLATLYPEN-- 252
            ||..|.|||.||| |.:..:....:...:::::..||:.|..:.|.|||.:|...:|..|||.  
Mouse   121 VALDLRGYGESDAPAHQESYKLDCLIADIKDILDSLGYSKCVLIGHDWGGMIAWLIAVCYPEMIM 185

  Fly   253 ---VIGY-HSNM---CVLHTPLAILKGIYGSFFPEKYLPSRFFVDHHFPVWEKWLELLEESGYFH 310
               ||.: |.::   .:|..|..:.:..:..||.....|...|..:.|    |.|:.|     |.
Mouse   186 KLIVINFPHPSVFTEYILRHPAQLFRSSFYYFFQIPRFPEFMFSINDF----KALKHL-----FT 241

  Fly   311 IQATKPDTIGAALTSSPVGLASYILEKFQTCTNPGLKQDFGAIVTVFGLEAVLDNLMVYY----- 370
            .|:|.....|..||:                      :|..|.|.||.....|...:.:|     
Mouse   242 SQSTGIGRKGRQLTT----------------------EDLEAYVYVFSQPGALSGPINHYRNIFS 284

  Fly   371 ---LTNSATTAARFYLENVSKTYRDLQLDRVQSPVPMGCARFRFDLASVTDWQLRDKFPNLTHSM 432
               |.:...|.....|......:.::                  ::|.||...:::.| .||   
Mouse   285 CLPLKHHMVTTPTLLLWGEEDAFMEV------------------EMAEVTKIYVKNYF-RLT--- 327

  Fly   433 YFQQGSHFAALEMPAMLFNDFTAFV 457
            ...:|||:...:.|.::.....||:
Mouse   328 ILSEGSHWLQQDQPDIVNGLIWAFL 352

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Jheh3NP_611387.1 EHN 60..165 CDD:283978 14/38 (37%)
Abhydrolase 135..>251 CDD:304388 37/124 (30%)
Ephx4NP_001001804.2 MhpC 74..353 CDD:223669 81/349 (23%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R2361
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.940

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