Protein Alignment Jheh3 and EPHX4

DIOPT Version :9

• Sequence 1: NP_611387.1
• Gene: Jheh3 / 37182
• FlyBaseID: FBgn0034406
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: NP_775838.3
• Gene: EPHX4 / 253152
• HGNCID: 23758
• Length: 362
• Species: Homo sapiens
• Alignment Length: 325
• Identity: 74/325 - (22%)
• Similarity: 117/325 - (36%)
• Gaps: 81/325 - (24%)

  Fly   134 GLNIHYIHEKVSEEAKEKKHVYPL-LLLHG-------WPGSVREFFDFIPMLTKHSNITDYAFEV 190
            ||..||:  ...|..|      || |||||       |...:|||              ...:.|
Human    80 GLRFHYV--AAGERGK------PLMLLLHGFPEFWYSWRYQLREF--------------KSEYRV 122

  Fly   191 VAPSLVGYGWSDAAT-RPGFNAAEMATVMRNLMLRLGHKKFFIQGGDWGSIIGSNLATLYPENVI 254
            ||..|.|||.:||.. |..:....:.|.:::::..||:.|..:.|.|||.:|...:|..|||.|:
Human   123 VALDLRGYGETDAPIHRQNYKLDCLITDIKDILDSLGYSKCVLIGHDWGGMIAWLIAICYPEMVM 187

  Fly   255 GY------HSNM---CVLHTPLAILKGIYGSFFPEKYLPSRFFVDHHFPVWEKWLELLEESGYFH 310
            ..      |.|:   .:|..|..:||..|..||...:.|...|..:.|.|.:.         .|.
Human   188 KLIVINFPHPNVFTEYILRHPAQLLKSSYYYFFQIPWFPEFMFSINDFKVLKH---------LFT 243

  Fly   311 IQATKPDTIGAALTSSPVGLASYILEKFQTCTNPGLKQDFGAIVTVFGLEAVLDNLMVYY----- 370
            ..:|.....|..||:                      :|..|.:.||.....|...:.:|
Human   244 SHSTGIGRKGCQLTT----------------------EDLEAYIYVFSQPGALSGPINHYRNIFS 286

  Fly   371 ---LTNSATTAARFYLENVSKTYRDLQLDRVQSPVPMGCARFRFDLASVTDWQLRDKFPNLTHSM 432
               |.:...|.....|...:..:.::::..|.........|... |:..:.|..:|: |::.:.:
Human   287 CLPLKHHMVTTPTLLLWGENDAFMEVEMAEVTKIYVKNYFRLTI-LSEASHWLQQDQ-PDIVNKL 349

  Fly   433  432
            Human   350  349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jheh3	NP_611387.1	EHN	60..165	CDD:283978	14/38 (37%)
		Abhydrolase	135..>251	CDD:304388	37/124 (30%)
EPHX4	NP_775838.3	MhpC	76..350	CDD:223669	74/325 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2361
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.940