Protein Alignment Jheh2 and C45B11.6

DIOPT Version :10

• Sequence 1: NP_611386.2
• Gene: Jheh2 / 37181
• FlyBaseID: FBgn0034405
• Length: 463
• Species: Drosophila melanogaster
• Sequence 2: NP_001122878.1
• Gene: C45B11.6 / 6418708
• WormBaseID: WBGene00045379
• Length: 457
• Species: Caenorhabditis elegans
• Alignment Length: 498
• Identity: 120/498 - (24%)
• Similarity: 216/498 - (43%)
• Gaps: 105/498 - (21%)

  Fly     8 ILVGALTILVAVGYKNYRDLSAPGKRP-DLDNNAYWGPTLKEPYRENKAILPFDISVKPEVIEDL 71
            :::...:||:::    |  :..|...| ::|.:.||  .|.:|.:::..|..|.|.:|    |..
 Worm    10 VVISIFSILLSI----Y--IHKPDFPPLEIDPDDYW--KLDDPEKDDDTIYSFTIDIK----ESE 62

  Fly    72 IGQLSRPLKAQAPLEGV-GFQYGFNANELAKVVKYWRDTYLPKWSEREEYLKKLDHYQTEIQGLK 135
            :......|:::..|..: ...|....|||.:|:..:      .|.:.:.:|.....|:|||:|||
 Worm    63 VSNFKEKLESERFLPTLYDTNYDNYLNELKQVLLGF------NWKQHQHFLNTFKQYKTEIEGLK 121

  Fly   136 IHFIHAKPSQVKGQKPKKVLPLLLMHGWPGTVREFYDFIPLLTTPSDKS-DY------VFEVIAP 193
            |||:  :.|.....|..:|:|||:.||:||:..:|:..||:||.||... |:      .||||.|
 Worm   122 IHFL--RVSTPPKDKKSRVVPLLIFHGFPGSFWDFFKIIPILTNPSRHGFDFGVEEAIQFEVIVP 184

  Fly   194 SLPGYGWSQGSSKTGFGVAQVAVVMRNLMLRVGFDKFLVQGGD-WGSIIGSNVASLFPENVLGYH 257
            ||||:.:|...:|.||.....|.::..||.|:..:.:.|.|.: :||.:.:.::||:|..:.|.|
 Worm   185 SLPGFIFSDKPTKQGFNAIATARIIAKLMYRLNLNNYFVHGTEGYGSDVATLLSSLYPTRIAGLH 249

  Fly   258 -SNMCGNNS------------PMGQL------------------KMVLASFFPSWFVDSEYADFY 291
             ||...|.:            .|||.                  :|            ::.||::
 Worm   250 LSNPFVNPTFSTFTLAKYALKAMGQKDEDRENQENRETGKDNRDQM------------TDLADYF 302

  Fly   292 KGLGHLFSTIMEEMGYAHIQASKPDTIGNALIDNPTGLASYI------LEKFSTWTNTAFRSLPD 350
            |         .::..|    .:.....|.|.:::|:|.|.||      |..|...||
 Worm   303 K---------QDKFAY----PTNSQAFGAAFLNSPSGTAKYIESRWKQLSTFFAETN-------- 346

  Fly   351 GGLTKRFTYDQLLDNVMIYYVTNSITTSMRLYSESMVASQFALAVDSVPIKAKAGCTRFAHEITH 415
              |.:.||.|::...:.:|::|:::.:::.:...|.   .|.....|..::.....:........
 Worm   347 --LNELFTMDEIATEIYLYWLTDTLPSALTILDSSF---NFESVWLSSQVRIPTAVSYSKQTPWR 406

  Fly   416 FSDSVLANKFPNLVHSTHHRDGGHFPAFELPQQLYDDFVSFVQ 458
            .|..:|.:::.||...:....||.|...:...::.:|..|||:
 Worm   407 CSKDILEDRYLNLTRISELPKGGMFHHLQDGHKIAEDIFSFVE 449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jheh2	NP_611386.2	EHN	56..170	CDD:461913	34/114 (30%)
		Abhydrolase_1	156..370	CDD:395444	67/258 (26%)
C45B11.6	NP_001122878.1	EHN	51..154	CDD:461913	34/114 (30%)
		alpha/beta hydrolases	140..378	CDD:473884	69/272 (25%)