Protein Alignment Jheh2 and ephx5

DIOPT Version :10

• Sequence 1: NP_611386.2
• Gene: Jheh2 / 37181
• FlyBaseID: FBgn0034405
• Length: 463
• Species: Drosophila melanogaster
• Sequence 2: XP_021336553.1
• Gene: ephx5 / 322331
• ZFINID: ZDB-GENE-030131-1050
• Length: 480
• Species: Danio rerio
• Alignment Length: 455
• Identity: 186/455 - (40%)
• Similarity: 253/455 - (55%)
• Gaps: 24/455 - (5%)

  Fly    10 VGALTILVAVGYKNYRDLSAPGKRPDLDNNAYWGPTLKEPYRENKAILPFDISVKPEVIEDLIGQ 74
            ||||     :.|.::|  ..|...|..|  .:||...|. ..|:|.|..|.:....|.||||..:
Zfish    36 VGAL-----LCYLSWR--KGPKTIPIGD--GWWGAGQKS-LTEDKTIQRFVVKTSVEEIEDLHKR 90

  Fly    75 LSRPLKAQAPLEGVGFQYGFNANELAKVVKYWRDTYLPKWSEREEYLKKLDHYQTEIQGLKIHFI 139
            :.. .:...|||...|.||||:..|.:||.|||..:  .|.::.:.:.:..|::|:|:|:.:||:
Zfish    91 IDL-TRFTDPLEDSKFNYGFNSTYLRRVVSYWRHQF--NWEKQVKVINQYPHFKTKIEGIDVHFV 152

  Fly   140 HAKPSQVKGQKPKKVLPLLLMHGWPGTVREFYDFIPLLTTPSDKSDYVFEVIAPSLPGYGWSQGS 204
            |.:|.|..||   .|:||:::|||||:..|||..|||||  ...|:.|||||.||:||||:|:..
Zfish   153 HVRPLQKSGQ---TVVPLMMVHGWPGSFYEFYGIIPLLT--KTDSNVVFEVICPSIPGYGYSEAP 212

  Fly   205 SKTGFGVAQVAVVMRNLMLRVGFDKFLVQGGDWGSIIGSNVASLFPENVLGYHSNM--CGNNSPM 267
            .|.||...:.|.:...||.|:||.:|.|||||||:.|.||:|.:.|:.|.|.|.||  ...:|..
Zfish   213 HKKGFNTMEAARIFLKLMERLGFSEFYVQGGDWGAFITSNMAQMKPDCVRGLHLNMVIARTDSTA 277

  Fly   268 GQLKMVLASFFP--SWFVDSEYADFYKGLGHLFSTIMEEMGYAHIQASKPDTIGNALIDNPTGLA 330
            ..|.:|:..:.|  ..|...:....|..:......|:.|.||.||||:||||.|..|.|:|.|||
Zfish   278 QLLSLVIGRYLPFLVGFTKEDVRRLYPYMEKNIYDILRETGYLHIQATKPDTAGCGLNDSPVGLA 342

  Fly   331 SYILEKFSTWTNTAFRSLPDGGLTKRFTYDQLLDNVMIYYVTNSITTSMRLYSESMVASQFALAV 395
            :|||||||||||...|.|.||||.::|..|.||.|||||:.|.||..|||.|.|:: ...|...|
Zfish   343 AYILEKFSTWTNLENRDLEDGGLERKFNLDDLLTNVMIYWTTCSIIPSMRFYKENL-KKDFKTRV 406

  Fly   396 DSV-PIKAKAGCTRFAHEITHFSDSVLANKFPNLVHSTHHRDGGHFPAFELPQQLYDDFVSFVQK 459
            |.| .|....|...|..|:.|...:..:::|.::...|:...||||.|||.||.|..|.:.|.:|
Zfish   407 DRVTSIHVPTGLAAFPDELLHCPRAWASSRFSDVRSFTYMPRGGHFAAFEEPQLLAQDIIQFAEK 471

  Fly   460  459
            Zfish   472  471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jheh2	NP_611386.2	EHN	56..170	CDD:461913	41/113 (36%)
		Abhydrolase_1	156..370	CDD:395444	105/217 (48%)
ephx5	XP_021336553.1	EHN	72..180	CDD:461913	41/113 (36%)
		Abhydrolase_1	166..396	CDD:395444	113/231 (49%)