Protein Alignment Jheh2 and Ephx1

DIOPT Version :10

• Sequence 1: NP_611386.2
• Gene: Jheh2 / 37181
• FlyBaseID: FBgn0034405
• Length: 463
• Species: Drosophila melanogaster
• Sequence 2: NP_036976.2
• Gene: Ephx1 / 25315
• RGDID: 2557
• Length: 455
• Species: Rattus norvegicus
• Alignment Length: 463
• Identity: 186/463 - (40%)
• Similarity: 271/463 - (58%)
• Gaps: 17/463 - (3%)

  Fly     4 IWPRILVGALTILVAVGYKNYRDLSAPGKRPDLDNNAYWGPTLKEPYRENKAILPFDISVKPEVI 68
            :|..:::.:|     :|:..|..:|...:......:.:|||..|...:|:::|.||.:....|.|
  Rat     1 MWLELVLASL-----LGFVIYWFVSRDKEETLPLGDGWWGPGSKPSAKEDESIRPFKVETSDEEI 60

  Fly    69 EDLIGQLSRPLKAQAPLEGVGFQYGFNANELAKVVKYWRDTYLPKWSEREEYLKKLDHYQTEIQG 133
            :||..::.| .:|..||||..|.||||:|.:.|||.|||:.:  .|.::.|.|.:..|::|:|:|
  Rat    61 KDLHQRIDR-FRASPPLEGSRFHYGFNSNYMKKVVSYWRNEF--DWRKQVEILNQYPHFKTKIEG 122

  Fly   134 LKIHFIHAKPSQV-KGQKPKKVLPLLLMHGWPGTVREFYDFIPLLTTPSD---KSDYVFEVIAPS 194
            |.|||||.||.|: .|:.||   |||::|||||:..|||..|||||.|..   ..::|||||.||
  Rat   123 LDIHFIHVKPPQLPSGRTPK---PLLMVHGWPGSFYEFYKIIPLLTDPKSHGLSDEHVFEVICPS 184

  Fly   195 LPGYGWSQGSSKTGFGVAQVAVVMRNLMLRVGFDKFLVQGGDWGSIIGSNVASLFPENVLGYHSN 259
            :||||:|:.|||.|......|.:...||.|:||.||.:|||||||:|.:|:|.:.|.:|.|.|.|
  Rat   185 IPGYGYSEASSKKGLNSVATARIFYKLMTRLGFQKFYIQGGDWGSLICTNMAQMVPNHVKGLHLN 249

  Fly   260 MCGNNSPMGQLKMVLASFFPSW--FVDSEYADFYKGLGHLFSTIMEEMGYAHIQASKPDTIGNAL 322
            |...:.....:..:|...|..:  :.:.:....|.....:|.:||.|.||.||||:||||:|.||
  Rat   250 MAFISRSFYTMTPLLGQRFGRFLGYTEKDIELLYPYKEKVFYSIMRESGYLHIQATKPDTVGCAL 314

  Fly   323 IDNPTGLASYILEKFSTWTNTAFRSLPDGGLTKRFTYDQLLDNVMIYYVTNSITTSMRLYSESMV 387
            .|:|.|||:||||||||||.:.:|.|.||||.::|:.|.||.|:|||:.|.:|.:|.|.|.|::.
  Rat   315 NDSPVGLAAYILEKFSTWTKSEYRELEDGGLERKFSLDDLLVNIMIYWTTGTIVSSQRYYKENLG 379

  Fly   388 ASQFALAVDSVPIKAKAGCTRFAHEITHFSDSVLANKFPNLVHSTHHRDGGHFPAFELPQQLYDD 452
            ........:.:.:....|.:.|..|:.|..:..:..|:|.|:..::...||||.|||.|:.|..|
  Rat   380 QGIMVHKHEGMKVFVPTGFSAFPSELLHAPEKWVKVKYPKLISYSYMERGGHFAAFEEPKLLAQD 444

  Fly   453 FVSFVQKA 460
            ...||..|
  Rat   445 IRKFVSLA 452

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jheh2	NP_611386.2	EHN	56..170	CDD:461913	52/114 (46%)
		Abhydrolase_1	156..370	CDD:395444	105/218 (48%)
Ephx1	NP_036976.2	EHN	48..157	CDD:461913	52/114 (46%)
		Abhydrolase_1	142..401	CDD:395444	114/261 (44%)