Protein Alignment Jheh2 and Ephx1

DIOPT Version :10

• Sequence 1: NP_611386.2
• Gene: Jheh2 / 37181
• FlyBaseID: FBgn0034405
• Length: 463
• Species: Drosophila melanogaster
• Sequence 2: NP_034275.1
• Gene: Ephx1 / 13849
• MGIID: 95405
• Length: 455
• Species: Mus musculus
• Alignment Length: 428
• Identity: 181/428 - (42%)
• Similarity: 257/428 - (60%)
• Gaps: 12/428 - (2%)

  Fly    39 NAYWGPTLKEPYRENKAILPFDISVKPEVIEDLIGQLSRPLKAQAPLEGVGFQYGFNANELAKVV 103
            :.:|||..|...:|:::|.||.:....|.|:||..::.| .:|..||||..|.||||::.|.|||
Mouse    31 DGWWGPGSKPSAKEDESIRPFKVETSDEEIKDLHQRIDR-FRASPPLEGSRFHYGFNSSYLKKVV 94

  Fly   104 KYWRDTYLPKWSEREEYLKKLDHYQTEIQGLKIHFIHAKPSQV-KGQKPKKVLPLLLMHGWPGTV 167
            .:||:.:  .|.::.|.|.:..|::|:|:||.|||||.||.|: .|:.||   |||::|||||:.
Mouse    95 SFWRNEF--DWRKQVEILNQYPHFKTKIEGLDIHFIHVKPPQLPSGRTPK---PLLMVHGWPGSF 154

  Fly   168 REFYDFIPLLTTPSD---KSDYVFEVIAPSLPGYGWSQGSSKTGFGVAQVAVVMRNLMLRVGFDK 229
            .|||..|||||.|..   ..::|||||.||:||||:|:.|||.|......|.:...||.|:||.|
Mouse   155 YEFYKIIPLLTDPKTHGLSDEHVFEVICPSIPGYGFSEASSKKGLNSVATARIFYKLMSRLGFQK 219

  Fly   230 FLVQGGDWGSIIGSNVASLFPENVLGYHSNMCGNNSPMGQLKMVLASFFPSW--FVDSEYADFYK 292
            |.:|||||||:|.:|:|.:.|.:|.|.|.||...:..:..|..:|...|..:  :.:.:....|.
Mouse   220 FYIQGGDWGSLICTNIAQMVPNHVKGLHLNMSFISRNIYSLTPLLGQRFGRFLGYTEKDLELLYP 284

  Fly   293 GLGHLFSTIMEEMGYAHIQASKPDTIGNALIDNPTGLASYILEKFSTWTNTAFRSLPDGGLTKRF 357
            ....:|..||.|.||.||||:||||:|.||.|:|.|||:||||||||||.:.:|.|.||||.::|
Mouse   285 FKEKVFYNIMRESGYLHIQATKPDTVGCALNDSPVGLAAYILEKFSTWTKSEYRELEDGGLERKF 349

  Fly   358 TYDQLLDNVMIYYVTNSITTSMRLYSESMVASQFALAVDSVPIKAKAGCTRFAHEITHFSDSVLA 422
            :.:.||.|:|||:.|.:|.:|.|.|.|::.........:.:.:....|.:.|..||.|..:..:.
Mouse   350 SLEDLLTNIMIYWTTGTIVSSQRFYKENLGQGVMVHRHEGMKVFVPTGYSAFPSEILHAPEKWVK 414

  Fly   423 NKFPNLVHSTHHRDGGHFPAFELPQQLYDDFVSFVQKA 460
            .|:|.|:..::...||||.|||.|:.|..|...||..|
Mouse   415 VKYPKLISYSYMERGGHFAAFEEPKLLAQDIRKFVSLA 452

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jheh2	NP_611386.2	EHN	56..170	CDD:461913	51/114 (45%)
		Abhydrolase_1	156..370	CDD:395444	105/218 (48%)
Ephx1	NP_034275.1	EHN	48..157	CDD:461913	51/114 (45%)
		Abhydrolase_1	142..349	CDD:395444	100/209 (48%)