Protein Alignment CG18190 and Mapre2

DIOPT Version :10

• Sequence 1: NP_611384.2
• Gene: CG18190 / 37179
• FlyBaseID: FBgn0034403
• Length: 248
• Species: Drosophila melanogaster
• Sequence 2: NP_001094470.1
• Gene: Mapre2 / 679221
• RGDID: 1590736
• Length: 326
• Species: Rattus norvegicus
• Alignment Length: 278
• Identity: 103/278 - (37%)
• Similarity: 154/278 - (55%)
• Gaps: 47/278 - (16%)

  Fly     4 LKLTVALTSVNAENMSRHDMLQWVNNMVHGHFKKIEELCSGAAYCQMMEMIFPNCINLKRVKMTA 68
            :.:.|..||:..|.|||||::.|||::|..::.|:|:|||||||||.|:|:||.||:||:||..|
  Rat    43 MAVNVYSTSITQETMSRHDIIAWVNDIVSLNYTKVEQLCSGAAYCQFMDMLFPGCISLKKVKFQA 107

  Fly    69 KLEHEYLHNLRLFQEAFNRLKLDKTVPIDRLIKGRFQDNFEFLQWFKKFFDSQAPGL-------- 125
            ||||||:||.:|.|.:|.|:.:||.:|:::|:|||||||.:|:||||||:|:...|.
  Rat   108 KLEHEYIHNFKLLQASFKRMNVDKVIPVEKLVKGRFQDNLDFIQWFKKFYDANYDGKEYDPVEAR 172

  Fly   126 ------------ENIKSL------ANAPLAKPIKPRQFAKERS----PVNA-----------NDD 157
                        |.|.:|      ||:|.|...|....||..|    |.:|           :|.
  Rat   173 QGQDAIPPPDPGEQIFNLPKKSHHANSPTAGAAKSSPAAKPGSTPSRPSSAKRASSSGSASRSDK 237

  Fly   158 ALK----ELIDEMKNLSLKREDIMEASNQIYNKLRLVEDLVNDMINNNQLVELCKRIQAVLYKTI 218
            .|:    :|.:::.:|.|..|.:.:..:..:.|||.:|.|..:....|.  :|.:|:..|||.:.
  Rat   238 DLETQVIQLNEQVHSLKLALEGVEKERDFYFGKLREIELLCQEHGQEND--DLVQRLMEVLYASD 300

  Fly   219 DGEINEEPVEVNEDNGDE 236
            :.|...|..||.|...|:
  Rat   301 EQEGQTEEPEVEEQTHDQ 318

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18190	NP_611384.2	BIM1	19..>124	CDD:227542	61/104 (59%)
		EB1	184..216	CDD:460870	10/31 (32%)
Mapre2	NP_001094470.1	BIM1	58..315	CDD:227542	97/258 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	170..239		14/68 (21%)
		DCTN1-binding. /evidence=ECO:0000250	186..326		35/135 (26%)
		APC-binding. /evidence=ECO:0000250	258..301		12/44 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	297..326		7/22 (32%)