DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG18190 and Mapre3

DIOPT Version :9

Sequence 1:	NP_611384.2	Gene:	CG18190 / 37179	FlyBaseID:	FBgn0034403	Length:	248	Species:	Drosophila melanogaster
Sequence 2:	NP_001007657.1	Gene:	Mapre3 / 298848	RGDID:	1359297	Length:	281	Species:	Rattus norvegicus

Alignment Length:	283	Identity:	98/283 - (34%)
Similarity:	151/283 - (53%)	Gaps:	48/283 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LKLTVALTSVNAENMSRHDMLQWVNNMVHGHFKKIEELCSGAAYCQMMEMIFPNCINLKRVKMTA 68
            :.:.|..|||.:||:||||||.|||:.:|.::.|||:|||||||||.|:|:||.|::|::||..|
  Rat     1 MAVNVYSTSVTSENLSRHDMLAWVNDSLHLNYTKIEQLCSGAAYCQFMDMLFPGCVHLRKVKFQA 65

  Fly    69 KLEHEYLHNLRLFQEAFNRLKLDKTVPIDRLIKGRFQDNFEFLQWFKKFFDSQAPGLENIKSLAN 133
            ||||||:||.::.|.||.::.:||.:|:::|:||:|||||||:||||||||:...|.:....||.
  Rat    66 KLEHEYIHNFKVLQAAFKKMGVDKIIPVEKLVKGKFQDNFEFIQWFKKFFDANYDGKDYNPLLAR 130

  Fly   134 -----APLAKP------------------------------------IKPRQFAKERSPVNAN-- 155
                 ||...|                                    :.|....::..|...|
  Rat   131 QGQDVAPPPNPGDQIFNKSKKLIGTAVPQRTSPTGPKNMQTSGRLSNVAPPCILRKNPPSARNGG 195

  Fly   156 ---DDALKELIDEMKNLSLKREDIMEASNQIYNKLRLVEDLVNDMINNNQLVELCKRIQAVLYKT 217
               |..:.||..::.:|.|..:.:.:..:..::|||.:|.:..:..:.|..|  ...|..:||.|
  Rat   196 HEADAQILELNQQLLDLKLTVDGLEKERDFYFSKLRDIELICQEHESENSPV--ISGIIGILYAT 258

  Fly   218 IDGEINEEPVEVNEDNGDEGAEH 240
            .:|....|..|:.|...::..|:
  Rat   259 EEGFAPPEDDEIEEHQQEDQDEY 281

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18190	NP_611384.2	CH	19..>92	CDD:278723	42/72 (58%)
CG18190	NP_611384.2	EB1	184..216	CDD:281288	8/31 (26%)
Mapre3	NP_001007657.1	BIM1	16..279	CDD:227542	91/264 (34%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	157..181		0/23 (0%)
		DCTN1-binding. /evidence=ECO:0000250	217..281		14/65 (22%)
		APC-binding. /evidence=ECO:0000250	217..260		10/44 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	260..281		4/20 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352818
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5217
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1237523at2759
OrthoFinder	1	1.000	-	-		FOG0000490
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10623
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X303
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	9	8.810