DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MetRS and aimp1a

DIOPT Version :9

Sequence 1:	NP_611382.1	Gene:	MetRS / 37177	FlyBaseID:	FBgn0034401	Length:	1022	Species:	Drosophila melanogaster
Sequence 2:	NP_001039316.1	Gene:	aimp1a / 562232	ZFINID:	ZDB-GENE-060825-144	Length:	315	Species:	Danio rerio

Alignment Length:	234	Identity:	52/234 - (22%)
Similarity:	83/234 - (35%)	Gaps:	95/234 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly   778 TLLLPAGHQIGKPAPLFAKLEQSFIDELKGKYGGAQATNDAAHSQISAADLEKAVQAQADKVREL 842
            :|...:||     .|...:|||                        .||:.|:.::....:|:.|
Zfish     6 SLFKMSGH-----TPSLMRLEQ------------------------KAAEAEQIIEYLKQQVQLL 41

  Fly   843 KASTKDKAIWQ---PEVTKLL----DLKKQLEEAKKKTATAAAPAATPAPSNGSQSVQDLEKAIQ 900
                |:|||.|   .|..||:    .|||.:||.||                     |.|:|
Zfish    42 ----KEKAIVQATLKEEKKLMVENAKLKKDIEELKK---------------------QLLDK--- 78

  Fly   901 EQGDKVRKLKGSTKDKTVWQPEVNILLDLKK---QLEAVQKAAKAAPAANAAPAASPAATA---- 958
                  .|::|              ::|:..   .::.|.|...|.|..:|:|:|:...|.
Zfish    79 ------EKMRG--------------VIDVPSTEFSVQCVSKPTSADPPVSASPSAASTKTPSAKN 123

  Fly   959 --DAAKVKALEDKIAQQAEKVRTLKATGDAAVWKPEVDI 995
              :|.|:||  :|..::.||........||.|....:|:
Zfish   124 NDEAKKMKA--EKKGEKKEKKAAAPPQEDAKVDVSRLDL 160

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MetRS	NP_611382.1	GstA	1..175	CDD:223698
		GST_N_family	1..65	CDD:238319
		GST_C_family	63..164	CDD:295467
		PRK12268	254..812	CDD:237029	7/33 (21%)
		MetRS_core	255..625	CDD:173907
		Anticodon_Ia_Met	634..763	CDD:153411
		MetRS_RNA	828..868	CDD:238475	14/46 (30%)
		MetRS_RNA	895..938	CDD:238475	6/45 (13%)
		MetRS_RNA	966..1009	CDD:238475	7/30 (23%)
aimp1a	NP_001039316.1	ATP-synt_B	<5..81	CDD:304375	30/137 (22%)
aimp1a	NP_001039316.1	tRNA_bind_EMAP-II_like	153..255	CDD:239198	2/8 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0143
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900