DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MetRS and aimp1b

DIOPT Version :9

Sequence 1:	NP_611382.1	Gene:	MetRS / 37177	FlyBaseID:	FBgn0034401	Length:	1022	Species:	Drosophila melanogaster
Sequence 2:	XP_021325469.1	Gene:	aimp1b / 494049	ZFINID:	ZDB-GENE-041212-13	Length:	346	Species:	Danio rerio

Alignment Length:	210	Identity:	45/210 - (21%)
Similarity:	76/210 - (36%)	Gaps:	46/210 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   847 KDKAIWQPEV---TKLL-----------DLKKQLEEAKKKTAT--------AAAPAAT------P 883
            |:||:.|..|   .|||           |||..|::.:|:.|.        :|:.|:|      |
Zfish    76 KEKAMLQASVREEKKLLVENAKLKKDIDDLKNLLQDTQKRKAVKLRQERALSASIASTSAQLGEP 140

  Fly   884 APS-NGSQSVQDLEKAIQEQGDKVRKLKG-STKDKTVWQPEVNI-----------LLDLKKQLEA 935
            ||| :.:.|...........|.:.|:.:| |.:...|...|..:           :||::|..::
Zfish   141 APSTHTAPSATQTHAHTHHDGRRRRERRGVSCESVCVLSREQKLDVSRLDLRVARILDVRKHPDS 205

  Fly   936 VQKAAKAAPAANAAPAASPAATADAAKVKALEDKIAQQAEKVRTLKATGDAAVWKPEVDILLSLK 1000
            .....:.......||....:...:....:.|...:......||::|..|..:..:     ||...
Zfish   206 ESLYVQEVELGEHAPRTVVSGLTNHVPPEQLLGSLVVLLCNVRSVKVRGVQSQAR-----LLCAV 265

  Fly  1001 NELAALTGTPVAGGQ 1015
            |:......||..|.|
Zfish   266 NQERMEPLTPPTGAQ 280

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MetRS	NP_611382.1	GstA	1..175	CDD:223698
		GST_N_family	1..65	CDD:238319
		GST_C_family	63..164	CDD:295467
		PRK12268	254..812	CDD:237029
		MetRS_core	255..625	CDD:173907
		Anticodon_Ia_Met	634..763	CDD:153411
		MetRS_RNA	828..868	CDD:238475	12/34 (35%)
		MetRS_RNA	895..938	CDD:238475	9/54 (17%)
		MetRS_RNA	966..1009	CDD:238475	8/42 (19%)
aimp1b	XP_021325469.1	PRK12267	<179..346	CDD:330948	18/107 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0143
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900