Protein Alignment CG15097 and Klhl28

DIOPT Version :10

• Sequence 1: NP_001261079.1
• Gene: CG15097 / 37172
• FlyBaseID: FBgn0034396
• Length: 743
• Species: Drosophila melanogaster
• Sequence 2: NP_079983.1
• Gene: Klhl28 / 66689
• MGIID: 1913939
• Length: 571
• Species: Mus musculus
• Alignment Length: 572
• Identity: 208/572 - (36%)
• Similarity: 325/572 - (56%)
• Gaps: 21/572 - (3%)

  Fly    49 HQNPGHCIASFA---------AINQMRNNAQLCDVRLEVGGDTINAHRVVLASVSPYFYAMFNDD 104
            |..|.:.:|:..         .:|.:|.:.:|||:.|.||...|:||:|||||:||||.|||..:
Mouse     3 HTAPTYMLANLTHLHSEQLLQGLNLLRQHHELCDIILRVGDVKIHAHKVVLASISPYFKAMFTGN 67

  Fly   105 MLERTQGLVRLHDVDSSALRQLIDYTYTGEITITEQNVQVLLPASGLLQMHSVRDACCKFLLRQL 169
            :.|:....|....:|.:||:.:::|.|||.:.|::..|:.||||:.|||:..|...||.||..||
Mouse    68 LSEKENSEVEFQCIDEAALQAIVEYAYTGTVFISQDTVESLLPAANLLQIKLVLKECCAFLESQL 132

  Fly   170 HPSNCLGIRSFADAHSCKELHTRSHKYALQNFQQVVGTEEFLLLPFEEVRELISNSQLNISSEER 234
            .|.||:||..||:.:.|.:|:..:.|:..|||:.|..||||..|...::.|::||..||:::||.
Mouse   133 DPGNCIGISRFAETYGCHDLYLAATKFICQNFESVCQTEEFFELTHADLDEIVSNDCLNVATEET 197

  Fly   235 VFAAVINWVKHDLPTRRLHIAELMSNVRLPLVSRDFLMSCVETETLMRDDSECKELLLEAMKYHL 299
            ||.|:.:|:|:|:..|:.::|:|:::|||||:|..||....|...|:|||..||.||.||:|||.
Mouse   198 VFYALESWIKYDVQERQKYLAQLLNSVRLPLLSVKFLTRLYEANHLIRDDRTCKHLLNEALKYHF 262

  Fly   300 LPEQRSIMGSQRTQERRPEGMKPYVFAVGGGS-LFAIHNECEVYNPRSNSWSPVAPMLWRRSRSG 363
            :||.|  :..|.....||......:.||||.| |||..:..|:|.|:::||..:||:...|...|
Mouse   263 MPEHR--LSHQTVLMTRPRCAPKVLCAVGGKSGLFACLDSVEMYFPQNDSWIGLAPLNIPRYEFG 325

  Fly   364 VTSLHKQLYVVGGYD-----GVS---DLATAESYNPLTNKWSNITPMGTKRSCLGICSYDALIYV 420
            :..|.::::|:||.:     |::   ...:.|.:||.||.|:::..|...||.||:......::.
Mouse   326 ICVLDQKVFVIGGIETSVRPGMTVRKHENSVECWNPDTNTWTSLERMNESRSTLGVAVLAGEVFA 390

  Fly   421 CGGYDGASCLSSMERYDPLTGIWSSCPAMSTRRRYCRLAVLENCIYSLGGFDSTNYQSSVERFDP 485
            .|||||.|.|.|:|:|.|....|.....|:|.|.....|||:..:|::||:... :.:||||:||
Mouse   391 LGGYDGQSYLQSVEKYIPKIRQWQPVAPMTTTRSCFAAAVLDGMLYAIGGYGPA-HMNSVERYDP 454

  Fly   486 RVGRWQPVPSMSARRSSCGVASTDGHLYCIGGNDGTMCMSSGERFSLRRNSWEPIAAMHSRRSTH 550
            ....|:.|..|:.:|...||....|.::.:||::|...:||.||:...:|.|.....|...|:..
Mouse   455 SKDSWEMVAPMADKRIHFGVGVMLGFIFVVGGHNGVSHLSSIERYDPHQNQWTVCRPMKEPRTGV 519

  Fly   551 EVVEVEGALFALGGNDGSSSLNSVERYDTRLNKWSVVNAMVARRSSVGAAVL 602
            ....::..|:.:||:.|||.||:|::||...:.|.....|:..|.:.|...|
Mouse   520 GAAVIDNYLYVVGGHSGSSYLNTVQKYDPISDTWLDSAGMIYCRCNFGLTAL 571

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15097	NP_001261079.1	BTB_POZ	51..171	CDD:453885	50/128 (39%)
		PHA03098	65..539	CDD:222983	186/482 (39%)
		BACK	169..282	CDD:475122	46/112 (41%)
		KELCH repeat	359..402	CDD:276965	13/50 (26%)
		KELCH repeat	406..450	CDD:276965	16/43 (37%)
		KELCH repeat	453..496	CDD:276965	15/42 (36%)
		KELCH repeat	500..545	CDD:276965	14/44 (32%)
		KELCH repeat	547..590	CDD:276965	13/42 (31%)
		Kelch	559..603	CDD:128874	16/44 (36%)
Klhl28	NP_079983.1	PHA03098	35..553	CDD:222983	197/520 (38%)
		Kelch 1	284..331		18/46 (39%)
		KELCH repeat	321..372	CDD:276965	13/50 (26%)
		Kelch 2	332..386		15/53 (28%)
		KELCH repeat	376..419	CDD:276965	16/42 (38%)
		Kelch 3	387..433		18/45 (40%)
		KELCH repeat	423..465	CDD:276965	15/42 (36%)
		Kelch 4	435..479		15/44 (34%)
		KELCH repeat	469..513	CDD:276965	13/43 (30%)
		Kelch 5	480..526		11/45 (24%)
		KELCH repeat	516..559	CDD:276965	13/42 (31%)
		Kelch 6	528..570		15/41 (37%)