Protein Alignment CG15097 and Klhl8

DIOPT Version :10

• Sequence 1: NP_001261079.1
• Gene: CG15097 / 37172
• FlyBaseID: FBgn0034396
• Length: 743
• Species: Drosophila melanogaster
• Sequence 2: NP_001099465.1
• Gene: Klhl8 / 289457
• RGDID: 1304685
• Length: 621
• Species: Rattus norvegicus
• Alignment Length: 545
• Identity: 206/545 - (37%)
• Similarity: 311/545 - (57%)
• Gaps: 14/545 - (2%)

  Fly    68 NAQLCDVRLEVGGDTINAHRVVLASVSPYFYAMFNDDMLERTQGLVRLHDVDSSALRQLIDYTYT 132
            |.:||||.|:||...|:.|::.||.|.|||.|||..:|.|..|.|:.:.|.|..|:..|:.:.|:
  Rat    64 NGELCDVTLKVGSKLISCHKLALACVIPYFRAMFLSEMSEAKQALIEIRDFDGDAVEDLVKFVYS 128

  Fly   133 GEITITEQNVQVLLPASGLLQMHSVRDACCKFLLRQLHPSNCLGIRSFADAHSCKELHTRSHKYA 197
            ..:|:|..|||.||.|:.:||:..|..|||:::....||||||.:|:||::|:..:|...:.:||
  Rat   129 SRLTLTVDNVQPLLYAACILQVELVARACCEYMKLHFHPSNCLAVRAFAESHNRTDLMDMADQYA 193

  Fly   198 LQNFQQVVGTEEFLLLPFEEVRELISNSQLNISSEERVFAAVINWVKHDLPTRRLHIAELMSNVR 262
            .::|.:||..|:|:.:..:.:.:|:|:|.|||.||::|::|.|.|:..:.......:.|.::.||
  Rat   194 CEHFTEVVECEDFVSVSPQHLHKLLSSSDLNIDSEKQVYSAAIKWLLANPQHHPKWLDETLAQVR 258

  Fly   263 LPLVSRDFLMSCVETETLMRDDSECKELLLEAMKYHLLPEQRSIMG---SQRTQERR-PEGMKPY 323
            |||:..||||..|..|.:::.:.:|::||.||..|||....:.:..   |.||..|: ..|:
  Rat   259 LPLLPVDFLMGVVAKEQIVKQNLKCRDLLDEARNYHLHLSSKPVPDFEYSVRTTPRKHTAGV--- 320

  Fly   324 VFAVGG----GSLFAIHNECEVYNPRSNSWSPVAPMLWRRSRSGVTSLHKQLYVVGGYDGVSDLA 384
            :|.|||    |..|   ...|.|:..:|||.....|..||...||.|:..::|.|||:||...|.
  Rat   321 LFCVGGRGGSGDPF---RSIECYSINTNSWFFGPEMNSRRRHVGVISVEGKVYAVGGHDGNEHLG 382

  Fly   385 TAESYNPLTNKWSNITPMGTKRSCLGICSYDALIYVCGGYDGASCLSSMERYDPLTGIWSSCPAM 449
            :.|.::||||||.....|.|||..:.:.|....||..||.|..:|.|.:||||..:..||:...|
  Rat   383 SMEMFDPLTNKWMVKASMNTKRRGIALASLGGPIYAIGGLDDNTCFSDVERYDIESDQWSTVAPM 447

  Fly   450 STRRRYCRLAVLENCIYSLGGFDSTNYQSSVERFDPRVGRWQPVPSMSARRSSCGVASTDGHLYC 514
            :|.|.......|.|.:|::||.|.....|||||:.|.:.:|..|..|..||:..||:...|.||.
  Rat   448 NTPRGGVGSVALINHVYAVGGNDGVASLSSVERYHPHLDKWVEVKEMGQRRAGNGVSELHGCLYV 512

  Fly   515 IGGNDGTMCMSSGERFSLRRNSWEPIAAMHSRRSTHEVVEVEGALFALGGNDGSSSLNSVERYDT 579
            :||.|....:||.||:..|.|.|:.:||:.:.|....:..|.|.:||:||::|::.||:||.:|.
  Rat   513 VGGFDDNSPLSSVERYDPRSNKWDYVAALTTPRGGVGIATVMGKIFAVGGHNGNAYLNTVEAFDP 577

  Fly   580 RLNKWSVVNAMVARRSSVGAAVLEC 604
            .||||.:|..:...|:..|.||.:|
  Rat   578 VLNKWELVGPVSHCRAGAGVAVCDC 602

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15097	NP_001261079.1	BTB_POZ	51..171	CDD:453885	42/102 (41%)
		PHA03098	65..539	CDD:222983	181/478 (38%)
		BACK	169..282	CDD:475122	42/112 (38%)
		KELCH repeat	359..402	CDD:276965	18/42 (43%)
		KELCH repeat	406..450	CDD:276965	15/43 (35%)
		KELCH repeat	453..496	CDD:276965	15/42 (36%)
		KELCH repeat	500..545	CDD:276965	18/44 (41%)
		KELCH repeat	547..590	CDD:276965	18/42 (43%)
		Kelch	559..603	CDD:128874	19/43 (44%)
Klhl8	NP_001099465.1	BTB_POZ_KLHL8	53..172	CDD:349547	47/107 (44%)
		PHA03098	61..536	CDD:222983	180/477 (38%)
		KELCH repeat	357..400	CDD:276965	18/42 (43%)
		KELCH repeat	404..448	CDD:276965	15/43 (35%)
		KELCH repeat	451..496	CDD:276965	16/44 (36%)
		KELCH repeat	498..543	CDD:276965	18/44 (41%)
		KELCH repeat	545..587	CDD:276965	18/41 (44%)
		Kelch	556..601	CDD:128874	19/44 (43%)