DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG15097 and Plekhn1

DIOPT Version :9

Sequence 1:NP_001261079.1 Gene:CG15097 / 37172 FlyBaseID:FBgn0034396 Length:743 Species:Drosophila melanogaster
Sequence 2:NP_001008234.2 Gene:Plekhn1 / 231002 MGIID:2387630 Length:611 Species:Mus musculus


Alignment Length:504 Identity:99/504 - (19%)
Similarity:159/504 - (31%) Gaps:176/504 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly   130 TYTGEITITEQNV-----------QVL--LPASGLLQMHS----------VRDACCKFLLRQLH- 170
            |:.|.:.:||.|:           |:.  |||..|:..||          :........|::.| 
Mouse   135 TFQGLLPLTELNICPTDGSREHAFQITGPLPAPLLVLCHSEAELSHWLYHLEKQMALLGLQRCHS 199

  Fly   171 --PSNCLGIR----SFADAHSCKELHTR--SHKYALQNFQQVVGTEEFLLLPFEEVRE---LISN 224
              |...||.:    ....|:.|..:...  :.:..||:            ||.:|..:   ::..
Mouse   200 APPQGSLGDKPPWTQLRRAYGCGSMSGAICASRVKLQH------------LPSQEQWDRLLVLYP 252

  Fly   225 SQLNISSEERVFAAVINWVKHDLPTRRLHI---------------AELMSNVRLPLVS-RDFLMS 273
            :.|.|.|||....:    .|.:||...:||               ..|::.:|:...| .|:...
Mouse   253 ASLAIFSEEPEGLS----FKGELPLSAIHINLEEKEKEIRSFLIEGHLINTIRVVCASYEDYSQW 313

  Fly   274 CVETETLMRDDSECKELLLEAMKYHLLPEQRSIMGSQRTQERRPEGMKPYVFAVGGGSLFAIHNE 338
            .:...|:.|.|..           ||.|...|..|.|:..:         :...|.|||.:    
Mouse   314 LLCLRTVSRRDGA-----------HLPPGPESFPGLQKPTQ---------LVGRGRGSLSS---- 354

  Fly   339 CEVYNPRSNSWS---PVAPMLWRRSRSGV-TSLHKQLYVVGGYDGVSDLATAESYNPLTNKWSNI 399
                |.|| ||.   ||.|.......|.| |::......|......:.::|.:  ..:....|:.
Mouse   355 ----NGRS-SWKLECPVFPTSQSLPESSVPTTIGFPAPPVPNQTDSNCVSTGQ--KKMKPSDSSP 412

  Fly   400 TPMG-------------------TKRSCLGICSYDALIYVCGGYDGASCLSSMERY-DPLTGIWS 444
            :|.|                   ||.|.|.:.|...      ..|.:..:.....| ||.|    
Mouse   413 SPRGRAQREVSGSTVPLPLPLDLTKMSALNLDSGPE------AQDHSLDIPHSPLYADPYT---- 467

  Fly   445 SCPAMSTRRRYCRLAVLENCIYSLGGFDSTNYQSSVERF------DPRVGRWQPVP----SMSAR 499
              |..::|.:          |..:.|.|        |:|      .|......|.|    |:...
Mouse   468 --PPATSRHK----------ITDIQGLD--------EQFLCAIQTSPGPDLSSPFPPVSVSVPVS 512

  Fly   500 RSSCGVASTDGHLYCIGGNDGTMCMSSGERFSLRRNSWEPIAAMHSRRS 548
            .||.|::|:.|.|              |.....::.:.:|.|:...|.|
Mouse   513 ESSSGISSSPGPL--------------GSHLLTKKGALQPRASQRHRGS 547

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG15097NP_001261079.1 BTB 63..166 CDD:279045 12/58 (21%)
PHA03098 65..539 CDD:222983 95/493 (19%)
BACK 174..276 CDD:285009 23/126 (18%)
Kelch 324..369 CDD:128874 15/48 (31%)
KELCH repeat 359..402 CDD:276965 6/43 (14%)
Kelch 370..415 CDD:128874 10/63 (16%)
KELCH repeat 406..450 CDD:276965 9/44 (20%)
Kelch 417..463 CDD:128874 7/46 (15%)
KELCH repeat 453..496 CDD:276965 8/52 (15%)
Kelch 464..510 CDD:128874 13/55 (24%)
Kelch_1 499..543 CDD:279660 9/43 (21%)
KELCH repeat 500..545 CDD:276965 9/44 (20%)
KELCH repeat 547..590 CDD:276965 1/2 (50%)
Kelch 559..603 CDD:128874
Plekhn1NP_001008234.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..30
Interaction with C1QBP. /evidence=ECO:0000250|UniProtKB:Q494U1 61..100
PH-like 96..188 CDD:302622 12/52 (23%)
PH-like 223..341 CDD:302622 28/144 (19%)
PH 243..322 CDD:278594 15/82 (18%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 327..357 11/46 (24%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 371..431 8/61 (13%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 443..473 7/41 (17%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 494..611 15/68 (22%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 1 0.900 - - OOG6_111129
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.