Protein Alignment CG15097 and Kbtbd2

DIOPT Version :10

• Sequence 1: NP_001261079.1
• Gene: CG15097 / 37172
• FlyBaseID: FBgn0034396
• Length: 743
• Species: Drosophila melanogaster
• Sequence 2: NP_666070.2
• Gene: Kbtbd2 / 210973
• MGIID: 2384811
• Length: 623
• Species: Mus musculus
• Alignment Length: 592
• Identity: 142/592 - (23%)
• Similarity: 246/592 - (41%)
• Gaps: 93/592 - (15%)

  Fly    73 DVRLEVGGDTINAHRVVLASVSPYFYAMFNDDMLERTQGLVRLHDVDSSALRQLIDYTYTGEITI 137
            |:.|.|.|.....|::|||:.|.||.|||...:.|..|..|.|.:||::||:.:|.|.|||.:.:
Mouse    32 DIVLIVEGTEFPCHKMVLATCSSYFRAMFMSGLSESKQTHVHLRNVDAAALQMIIAYAYTGNLAV 96

  Fly   138 TEQNVQVLLPASGLLQMHSVRDACCKFLLRQLHPSNCLGIRSFADAHSCKELHTRSHKYALQNFQ 202
            .:..|:.|...:..||:..|...|.::|:::::..||:.:.||||..||:||...:.:.....|.
Mouse    97 NDSTVEQLYETACFLQVEDVLQRCREYLIKKINAENCVRLLSFADLFSCEELKQSAKRMVEHKFT 161

  Fly   203 QVVGTEEFLLLPFEEVRELISNSQLNISSEERVFAAVINWVKHDLPTRRLHIAELMSNVRLPLVS 267
            .|...|.|:.|..:.:.:::|:..||:..||.|..|.:.|::::..:|..:::.::|.:|:..:|
Mouse   162 AVYRQEAFMQLSHDLLIDILSSDNLNVEKEETVREAAMLWLEYNTESRSQYLSSVLSQIRIDALS 226

  Fly   268 RDFLMSCVETETLMRDDSECKELLLEAMKYHLLPEQRSIMGSQRTQERRPEGMKPYVFAVGGGSL 332
                                 |:...|....|.|..:|:: .|...:..|:..||.:.......:
Mouse   227 ---------------------EVTQRAWFQGLPPNDKSVV-VQGLYKSMPKFFKPRLGMTKEEMM 269

  Fly   333 FAI----HNECEVYNPRSNSWSPVAPMLWRRSRSGVTSLHK---------QLYVVGG-------- 376
            ..|    .|.|.:|:  |..:||.|..:::.. |....|||         .:|:.||
Mouse   270 IFIEASSENPCSLYS--SVCYSPQAEKVYKLC-SPPADLHKVGTVVTPDNDIYIAGGQVPLKNTK 331

  Fly   377 --YDGVSDLATAES-------YNPLTNKWSNITPMGTKRSCLGICSYDALIYVCGG--YDGASCL 430
              :...|.|.||..       ::...|.|...|||...|....:...:..||..||  ..|....
Mouse   332 TNHSKTSKLQTAFRTVNCFYWFDAQQNTWFPKTPMLFVRVKPSLVCCEGYIYAIGGDSVGGELNR 396

  Fly   431 SSMERYDPLTGIWSSCPAMSTRRRYCRLAVLENCIYSLGGFDSTNYQSSVERFDPRVGRWQPVPS 495
            .::||||.....|:....:....::....|:.:|||.:    :.|....   :.||...|..:..
Mouse   397 RTVERYDTEKDEWTMVSPLPCAWQWSAAVVVHDCIYVM----TLNLMYC---YFPRSDSWVEMAM 454

  Fly   496 MSARRSSCGVASTDGHLYCIGG-----NDGTMCMSSG---------ERFSLRRNSWEPIAAMHSR 546
            ....||....|:....::.|||     |.| :.:.||         |.:.:.:|.|:..|.:.::
Mouse   455 RQTSRSFASAAAFGDKIFYIGGLHIATNSG-IRLPSGTVDGSSVTVEIYDVNKNEWKMAANIPAK 518

  Fly   547 RSTHEVVEVEGALFALGGNDGSSSLNS-----VERYDTRLNKWSVVNAMVAR---------RSSV 597
            |.:...|.......:|......:.||.     ..:||..|::||:...:..|         |.:|
Mouse   519 RYSDPCVRAVVISNSLCVFMRETHLNERAKYVTYQYDLELDRWSLRQHISERVLWDLGRDFRCTV 583

  Fly   598 GAAVLEC 604
            |.....|
Mouse   584 GKLYPSC 590

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15097	NP_001261079.1	BTB_POZ	51..171	CDD:453885	34/97 (35%)
		PHA03098	65..539	CDD:222983	126/511 (25%)
		BACK	169..282	CDD:475122	27/112 (24%)
		KELCH repeat	359..402	CDD:276965	14/68 (21%)
		KELCH repeat	406..450	CDD:276965	11/45 (24%)
		KELCH repeat	453..496	CDD:276965	8/42 (19%)
		KELCH repeat	500..545	CDD:276965	14/58 (24%)
		KELCH repeat	547..590	CDD:276965	10/47 (21%)
		Kelch	559..603	CDD:128874	12/57 (21%)
Kbtbd2	NP_666070.2	BTB_POZ_KBTBD2_BKLHD1	5..137	CDD:349579	36/104 (35%)
		PHA03098	23..516	CDD:222983	127/516 (25%)
		BACK_KBTBD2	128..223	CDD:350554	26/94 (28%)
		KELCH repeat	310..366	CDD:276965	10/55 (18%)
		Kelch 1. /evidence=ECO:0000255	317..380		13/62 (21%)
		KELCH repeat	374..415	CDD:276965	10/40 (25%)
		Kelch 2. /evidence=ECO:0000255	381..429		11/47 (23%)
		KELCH repeat	419..456	CDD:276965	8/43 (19%)
		Kelch 3. /evidence=ECO:0000255	431..469		9/44 (20%)
		KELCH repeat	459..516	CDD:276965	14/57 (25%)
		Kelch 4. /evidence=ECO:0000255	470..529		13/59 (22%)
		KELCH repeat	519..568	CDD:276965	10/48 (21%)
		Kelch 5. /evidence=ECO:0000255	535..581		8/45 (18%)