Protein Alignment CG15097 and Ivns1abp

DIOPT Version :10

• Sequence 1: NP_001261079.1
• Gene: CG15097 / 37172
• FlyBaseID: FBgn0034396
• Length: 743
• Species: Drosophila melanogaster
• Sequence 2: NP_473443.2
• Gene: Ivns1abp / 117198
• MGIID: 2152389
• Length: 642
• Species: Mus musculus
• Alignment Length: 624
• Identity: 174/624 - (27%)
• Similarity: 285/624 - (45%)
• Gaps: 101/624 - (16%)

  Fly    57 ASFAAINQMRNNAQLCDVRLEVGGDTINAHRVVLASVSPYFYAMFNDDMLERTQGLVRLHDVDSS 121
            :|.|.:|.:|.:.|.|||||:|.|..:.|||.|||..|||.:.:||.|........|:|.|::..
Mouse    17 SSVAKLNALRKSGQFCDVRLQVCGHEMLAHRAVLACCSPYLFEIFNSDSDPHGVSHVKLDDLNPE 81

  Fly   122 ALRQLIDYTYTGEITITEQNVQVLLPASGLLQMHSVRDACCKFLLRQLHPSNCLGIRSFADAHSC 186
            |:..|::|.||.::...::.|:.:..|:..|:|..|:..|..:||.::..::|:..|:||.....
Mouse    82 AVEVLLNYAYTAQLKADKELVKDVYSAAKKLKMDRVKQVCGDYLLSRMDVTSCISYRNFASCMGD 146

  Fly   187 KELHTRSHKYALQNFQQVVGTEEFLLLPFEEVRELISNSQLNISSEERVFAAVINWVKHDLPTRR 251
            ..|..:...|..::..|:...||||.||..:: |::....:.:.|..:::..|||||:..:....
Mouse   147 SRLLNKVDAYIQEHLLQISEEEEFLKLPRLKL-EVMLEDNVCLPSNGKLYTKVINWVQRSIWENG 210

  Fly   252 LHIAELMSNVRLPLVSRDFLM-----SCVETETLMRDDSECK----------------------- 288
            ..:.|||..|:....|.|..:     ...:.|....||...:
Mouse   211 DSLEELMEEVQTLYYSADHKLLDGNPLDGQAEVFGSDDDHIQFVQKKPPRENGHKQISGSSTGCL 275

  Fly   289 ---ELLLEAMKYHLLPEQRSIMGSQRTQ------------------------------------- 313
               ...:::.|:     :..|:.|::|.
Mouse   276 SSPNASMQSPKH-----EWKIVASEKTSNNTYLCLAVLDSTFCVIFLHGRNSPQSSPTSTPKLSK 335

  Fly   314 ----ERRPE-----GMKPYVFAVGG-------GSLFAI----HNEC----EVYNPRSNSWSPVAP 354
                |.:|:     .|.|..:|..|       |.|.|.    ..||    |.|:|.::.||.:||
Mouse   336 SLSFEMQPDELLEKPMSPMQYARSGLGTAEMNGKLIAAGGYNREECLRTVECYDPHTDHWSFLAP 400

  Fly   355 MLWRRSRSGVTSLHKQLYVVGGYDGVS-DLATAESYNPLTNKWSNITPMGTKRSCLGICSYDALI 418
            |...|:|..:..|..|||||||.:|.| ||:..|.|:|..:.|:.:..:.|.|...|:|:.:..:
Mouse   401 MRTPRARFQMAVLMGQLYVVGGSNGHSDDLSCGEMYDPNIDDWTPVPELRTNRCNAGVCALNGKL 465

  Fly   419 YVCGGYD--GASCLSSMERYDPLTGIWSSCPAMSTRRRYCRLAVLENCIYSLGGFDSTNYQSSVE 481
            |:.||.|  |...|.:.:.:||:|..|:||..::.||....:..|...:|.:||.:|.|..::||
Mouse   466 YIVGGSDPYGQKGLKNCDVFDPVTKSWTSCAPLNIRRHQSAVCELGGYLYIIGGAESWNCLNTVE 530

  Fly   482 RFDPRVGRWQPVPSMSARRSSCGVASTDGHLYCIGGNDGTMCMSSGERFSLRRNSWEPIAAMHSR 546
            |::|....|..:..|:..|...|||..||.|:..||.||:..:|..|.:...||.|:.:..|.|.
Mouse   531 RYNPENNTWTLIAPMNVARRGAGVAVLDGKLFVGGGFDGSHAISCVEMYDPTRNEWKMMGNMTSP 595

  Fly   547 RSTHEVVEVEGALFALGGNDGSSSLNSVERYDTRLNKWS 585
            ||...:..|...::|:||.||:..||:||.|:.:.|:||
Mouse   596 RSNAGITTVGNTIYAVGGFDGNEFLNTVEVYNPQSNEWS 634

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15097	NP_001261079.1	BTB_POZ	51..171	CDD:453885	40/113 (35%)
		PHA03098	65..539	CDD:222983	153/568 (27%)
		BACK	169..282	CDD:475122	27/117 (23%)
		KELCH repeat	359..402	CDD:276965	18/43 (42%)
		KELCH repeat	406..450	CDD:276965	15/45 (33%)
		KELCH repeat	453..496	CDD:276965	12/42 (29%)
		KELCH repeat	500..545	CDD:276965	17/44 (39%)
		KELCH repeat	547..590	CDD:276965	16/39 (41%)
		Kelch	559..603	CDD:128874	13/27 (48%)
Ivns1abp	NP_473443.2	BTB_POZ_NS1BP	14..137	CDD:349615	41/119 (34%)
		BACK_NS1BP_IVNS1ABP	129..225	CDD:350577	24/96 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	257..281		0/23 (0%)
		NanM	349..627	CDD:442289	95/277 (34%)
		KELCH repeat	358..401	CDD:276965	12/42 (29%)
		Kelch 1	369..415		15/45 (33%)
		KELCH repeat	405..450	CDD:276965	18/44 (41%)
		Kelch 2	416..463		19/46 (41%)
		KELCH repeat	453..498	CDD:276965	15/44 (34%)
		Kelch 3	465..512		15/46 (33%)
		KELCH repeat	502..545	CDD:276965	12/42 (29%)
		Kelch 4	513..559		15/45 (33%)
		KELCH repeat	549..593	CDD:276965	16/43 (37%)
		Kelch 5	561..606		15/44 (34%)
		KELCH repeat	596..635	CDD:276965	16/39 (41%)
		Kelch 6	608..642		13/27 (48%)