DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15097 and ivns1abp

DIOPT Version :9

Sequence 1:	NP_001261079.1	Gene:	CG15097 / 37172	FlyBaseID:	FBgn0034396	Length:	743	Species:	Drosophila melanogaster
Sequence 2:	XP_012816907.1	Gene:	ivns1abp / 100145550	XenbaseID:	XB-GENE-949332	Length:	665	Species:	Xenopus tropicalis

Alignment Length:	636	Identity:	168/636 - (26%)
Similarity:	291/636 - (45%)	Gaps:	89/636 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 GPNEEVLPQA--HHQNPGHCIASFAAINQMRNNAQLCDVRLEVGGDTINAHRVVLASVSPYFYAM 100
            |.:.:::|..  :.::.....:|.|.:|.:|.:.|.|||:|:|.|..:.|||.|||..||:.:.:
Frog    23 GTHRKMVPNGSLNFEDEQFIESSVAKLNALRKSGQFCDVKLQVCGHEMLAHRAVLACCSPFLFEI 87

  Fly   101 FNDDMLERTQGLVRLHDVDSSALRQLIDYTYTGEITITEQNVQVLLPASGLLQMHSVRDACCKFL 165
            ||.|.......|||..|::..|:..|::|.||.::......|:.:..|:..|::..|:..|..:|
Frog    88 FNSDGESHGISLVRFDDLNPDAVEVLLNYAYTSQLKAETDLVKDVYSAAKKLKIDRVKQVCGDYL 152

  Fly   166 LRQLHPSNCLGIRSFADAHSCKELHTRSHKYALQNFQQVVGTEEFLLLPFEEVRELISNSQLNIS 230
            |.::...:|:..|:|.:|.....|.::...|..::..::...|:||.||...: |::....:::.
Frog   153 LSKIDVQSCISYRNFVNAMGDWRLLSKIDNYIQEHLLEISEQEDFLKLPRLNL-EIMLEENVSLP 216

  Fly   231 SEERVFAAVINWVKHDLPTRRLHIAELMSNVRLPLVSRDFLM----------------------- 272
            |..:::..|||||:..:.....::..|:..|:....|.|..:
Frog   217 SNGKLYTKVINWVQRSIWENGENLDALLEEVQTLYYSADHKLLDASLLGEHTDAYEDNIQLIQKK 281

  Fly   273 -------------------------------SCVETETLMRDDSECKELLLEAMKYHLLPEQRSI 306
                                           ..:.:|....:...|..:|...:....|..:.|.
Frog   282 SPRENNHKNLSSSSSGSLSPTALTQSPKHEWKIIASEKKTNNTYLCLAVLNSMLCVIFLHGRNSP 346

  Fly   307 MGSQRTQER---------RPEG-----MKPYVFAVGG-------GSLFAI----HNEC----EVY 342
            :.|..:..|         :|:.     |.|..:|..|       |.|.|.    ..||    |.|
Frog   347 VNSPSSTPRLTKSLSLEIQPDDSLERVMSPMHYARSGLGTAELNGKLIAAGGYNREECLRTVECY 411

  Fly   343 NPRSNSWSPVAPMLWRRSRSGVTSLHKQLYVVGGYDGVS-DLATAESYNPLTNKWSNITPMGTKR 406
            :|.::.|:.:|||...|:|..:..|...||||||.:|.| ||:..|.|:|.:|.|.::..:.:.|
Frog   412 DPETDIWTFIAPMKTPRARFQMAVLMDHLYVVGGSNGHSDDLSCGEKYDPKSNVWISVPELRSNR 476

  Fly   407 SCLGICSYDALIYVCGGYD--GASCLSSMERYDPLTGIWSSCPAMSTRRRYCRLAVLENCIYSLG 469
            ...|:|:.:..:||.||.|  |...|.:.:.:||:|.:|:.|..::.||....:..|.|.:|.:|
Frog   477 CNAGVCALNGKLYVVGGSDPYGQKGLKNCDVFDPITRMWTCCAQLNIRRHQSAVCELGNKMYIIG 541

  Fly   470 GFDSTNYQSSVERFDPRVGRWQPVPSMSARRSSCGVASTDGHLYCIGGNDGTMCMSSGERFSLRR 534
            |.:|.|..:|||.::|....|..|..|:..|...|||..:|.|:.:||.|||..:|..|.:...|
Frog   542 GAESWNCLNSVECYNPENDTWTLVAPMNVARRGAGVAVYEGKLFVVGGFDGTHALSCVESYDPER 606

  Fly   535 NSWEPIAAMHSRRSTHEVVEVEGALFALGGNDGSSSLNSVERYDTRLNKWS 585
            |.|:.:.:|.|.||...:|.|...::|.||.||:..||::|.|:.:..:||
Frog   607 NEWKMMGSMTSARSNAGMVAVGDQIYAAGGFDGNEFLNTIEVYNPQTEEWS 657

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15097	NP_001261079.1	BTB	63..166	CDD:279045	34/102 (33%)
		PHA03098	65..539	CDD:222983	146/559 (26%)
		BACK	174..276	CDD:285009	22/155 (14%)
		Kelch	324..369	CDD:128874	17/59 (29%)
		KELCH repeat	359..402	CDD:276965	18/43 (42%)
		Kelch	370..415	CDD:128874	18/45 (40%)
		KELCH repeat	406..450	CDD:276965	15/45 (33%)
		Kelch	417..463	CDD:128874	15/47 (32%)
		KELCH repeat	453..496	CDD:276965	14/42 (33%)
		Kelch	464..510	CDD:128874	16/45 (36%)
		Kelch_1	499..543	CDD:279660	16/43 (37%)
		KELCH repeat	500..545	CDD:276965	17/44 (39%)
		KELCH repeat	547..590	CDD:276965	15/39 (38%)
		Kelch	559..603	CDD:128874	11/27 (41%)
ivns1abp	XP_012816907.1	BTB_POZ_NS1BP	41..164	CDD:349615	39/122 (32%)
		PHA03098	50..665	CDD:222983	164/609 (27%)
		KELCH repeat	381..424	CDD:276965	11/42 (26%)
		KELCH repeat	428..473	CDD:276965	18/44 (41%)
		KELCH repeat	476..521	CDD:276965	15/44 (34%)
		KELCH repeat	525..568	CDD:276965	14/42 (33%)
		KELCH repeat	572..616	CDD:276965	16/43 (37%)
		KELCH repeat	619..662	CDD:276965	15/39 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D312716at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010