DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15096 and slc17a7

DIOPT Version :9

Sequence 1:	NP_611376.1	Gene:	CG15096 / 37170	FlyBaseID:	FBgn0034394	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_001072608.1	Gene:	slc17a7 / 780064	XenbaseID:	XB-GENE-5742677	Length:	576	Species:	Xenopus tropicalis

Alignment Length:	450	Identity:	149/450 - (33%)
Similarity:	242/450 - (53%)	Gaps:	13/450 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 GLGVRHFQVLLLFFALTVAYGCRVNLSVAVVAMTDAASVNP------DFPEYNWSEKTKSLLLSS 90
            ||..|:...::......:::|.|.||.||:|:|.:..:|..      :..::.|..:|..::..|
Frog    58 GLPRRYIIAIMSGLGFCISFGIRCNLGVAIVSMVNNNTVYKGNKIVIEQAQFTWDPETVGMIHGS 122

  Fly    91 FFWGYVITQVPAGQLARKYGGKVMILSGLAICSILNILTPICAKIGGWQLVCALRVVEGLCQGVV 155
            |||||::||:|.|.:.:|:....:....:...|.||:|.|..|::....::| :|:::||.:||.
Frog   123 FFWGYIVTQIPGGYICQKFAANRVFGFAIVATSTLNMLIPSAARVHFACVIC-VRILQGLVEGVT 186

  Fly   156 FPSTHTILSQWAPPKERATLGTCAYSGNQFGTILMLATSGVIAASPIGWPSIFYISGGIGCVWSV 220
            :|:.|.|.|:||||.||:.|.|.|:.|:..|.::.:..:||:.... ||.|:||:.|..|.:|.:
Frog   187 YPACHGIWSKWAPPLERSRLATTAFCGSYAGAVVAMPLAGVLVQYS-GWSSVFYVYGSFGIMWYM 250

  Fly   221 VYFFFGAGSPQECKSISAEEKKLIEMSQADEVSGGQEQPKEQLPTPWLSFFTSPAFLVLIVSHSV 285
            .:......||....:||.||||.||.|..:  |.|...|..:...||..||||.....:||::..
Frog   251 FWILVSYESPAIHPTISEEEKKYIEESIGE--STGLMNPMAKFKAPWRKFFTSMPVYAIIVANFC 313

  Fly   286 HNWGFWTLLTEIPSYMKNILGKDIKSNALLSSLPYVCMFAMSFVFSSISAQLNNRNCISRSTSRK 350
            .:|.|:.||...|:|.:.:.|.:|....|||:||::.|..:..:...|:..|..:..:|.:..||
Frog   314 RSWTFYLLLISQPAYFEEVFGFEISKVGLLSALPHLVMTIIVPIGGQIADFLRTKRIMSTTNVRK 378

  Fly   351 LFNSIGLWIPMVTLVGLGYVNPDQSELAVVLLCFTVGMNGATYLGFNTNHIDLSPNFAGILMGIT 415
            :.|..|..:....|:.:||.:  ...:|:..|...||.:|....|||.||:|::|.:|.|||||:
Frog   379 MMNCGGFGMEATLLLVVGYSH--SRGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGIS 441

  Fly   416 NGVANIMSIIAPLIVGFIVTNEHDPEQWRIVFFIAAGFYLVGNTLYVIFGKANVQPWNDP 475
            |||..:..::.||||| .:|.....|:|:.||.||:..:..|...|.||.....|||.:|
Frog   442 NGVGTLSGMVCPLIVG-AMTKHKTREEWQYVFLIASLVHYGGVLFYGIFASGEKQPWAEP 500

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15096	NP_611376.1	2A0114euk	36..480	CDD:129972	146/445 (33%)
CG15096	NP_611376.1	MFS	40..464	CDD:119392	140/429 (33%)
slc17a7	NP_001072608.1	2A0114euk	62..503	CDD:129972	146/445 (33%)
		MFS	67..490	CDD:119392	141/429 (33%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	517..547
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	52	1.000	Domainoid score	I11242
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53923
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.930