DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15096 and Slc17a4

DIOPT Version :9

Sequence 1:	NP_611376.1	Gene:	CG15096 / 37170	FlyBaseID:	FBgn0034394	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_001258143.1	Gene:	Slc17a4 / 679784	RGDID:	1584758	Length:	495	Species:	Rattus norvegicus

Alignment Length:	506	Identity:	155/506 - (30%)
Similarity:	251/506 - (49%)	Gaps:	64/506 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 DMEAK--------NSNKEDEAVGKHSGLGVRHFQVLLLFFALTVAYGCRVNLSVAVVAM--TDAA 68
            |::|:        |.|...|...|.....:||....:|.......|..::|||:|:.||  |.||
  Rat     6 DLKAREGGIPNDSNLNMTQEQSFKKGCCSLRHGLAFILHLCNFSVYTQQMNLSIAITAMVNTTAA 70

  Fly    69 SV------------NPDF----------PEYNWSEKTKSLLLSSFFWGYVITQVPAGQLARKYGG 111
            |.            :.||          |.|:|:.:.:.:||||..:|..:..:|.|.:|..:|.
  Rat    71 SSHANASIERPTTDSQDFWNETLQESKAPVYDWTPEIQGILLSSLNYGSFLAPIPTGYVAGVFGA 135

  Fly   112 KVMILSGLAICSILNILTPICAKIGGWQLVCALRVVEGLCQGVVFPSTHTILSQWAPPKERATLG 176
            |.::..||.:.|:|.:..|:.|: .|..|:..|||::|:.|.:|....:::.::||||.||:.|.
  Rat   136 KYVVGLGLLVSSVLTLFIPLAAE-AGVALLIVLRVIQGMSQVMVLTGQYSMWAKWAPPLERSQLI 199

  Fly   177 TCAYSGNQFGTILMLATSGVIAASPIGWPSIFYISGGIGCVWSVVYFFFGAGSPQECKSISAEEK 241
            |.|.||:..||.|:|...|::..: :|||.||||.|||||...:::|......||....||..||
  Rat   200 TIAASGSMLGTFLVLIAGGLLCQA-LGWPYIFYIFGGIGCACCLLWFPLVYDDPQNHPFISTGEK 263

  Fly   242 KLIEMSQADE-VSGGQEQP----KEQLPTPWLSFFTSPAFLVLIVSHSVHNWGFWTLLTEIPSYM 301
            :.|..|.|.| .|.|...|    .:.||. |          .::||:....|..:|::...|:|:
  Rat   264 RYIMCSLAQEDCSLGWSLPIKAMVKSLPL-W----------AIVVSYFCEYWLLFTIMAYTPTYI 317

  Fly   302 KNILGKDIKSNALLSSLPYVCMF-AMSFVFSSISAQ-LNNRNCISRSTSRKLFNSIGLWIPMVTL 364
            .::|..:::.:.:||:||:  || .:..:...:.|. |.:||.:...|.||||.::|:.:....|
  Rat   318 SSVLQANLRDSGILSALPF--MFGCVCIILGGLLADFLLSRNILRLVTIRKLFTALGVLVSSGIL 380

  Fly   365 VGLGYVNPDQSELAVVLLCFTVGM----NGATYLGFNTNHIDLSPNFAGILMGITNGVANIMSII 425
            |.|.:|:...|.....|:..:|..    :||.     .|.:|::|.:||.|.|:....:.:...|
  Rat   381 VPLPWVSSSLSTTMAFLVLSSVFASLCDSGAL-----INFLDIAPRYAGFLKGLLQVFSYLAGGI 440

  Fly   426 APLIVGFIVTNEHDPEQWRIVFFIAAGFYLVGNTLYVIFGKANVQPWNDPP 476
            ||.:.||.::.:.: ..||.||.:||...:||...|:|||:|.||.|...|
  Rat   441 APTVAGFFISQDSE-FGWRNVFLLAAAIDVVGLLFYLIFGRAEVQDWAKEP 490

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15096	NP_611376.1	2A0114euk	36..480	CDD:129972	149/476 (31%)
CG15096	NP_611376.1	MFS	40..464	CDD:119392	139/458 (30%)
Slc17a4	NP_001258143.1	MFS_SLC17	40..479	CDD:340876	140/459 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342518
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840