DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG15096 and CG3036

DIOPT Version :9

Sequence 1:	NP_611376.1	Gene:	CG15096 / 37170	FlyBaseID:	FBgn0034394	Length:	491	Species:	Drosophila melanogaster
Sequence 2:	NP_001260058.1	Gene:	CG3036 / 33695	FlyBaseID:	FBgn0031645	Length:	493	Species:	Drosophila melanogaster

Alignment Length:	497	Identity:	152/497 - (30%)
Similarity:	248/497 - (49%)	Gaps:	66/497 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 VRHF----QV--LLLFFALTVAYGCRVNLSVAVVAM-----TDA-------------ASVNPD-- 73
            ||:|    ||  ||......:.|..||||::|:|.|     |.|             ::.:||
  Fly    12 VRNFLSCRQVLNLLTMLGFMLNYALRVNLTIAIVDMVRPNVTSAVNATLVGNSTAANSTASPDGV 76

  Fly    74 ------FPEYNWSEKTKSLLLSSFFWGYVITQVPAGQLARKYGGKVMILSGLAICSILNILTPIC 132
                  ||   |.....:.:|..|||||::|::|.|:||...||:.:....:...|:|.::||:.
  Fly    77 DVYEERFP---WDSYQTNFVLGCFFWGYILTELPGGRLAELIGGRRVFGHSMLWASLLTLITPLA 138

  Fly   133 AKIGGWQLVCALRVVEGLCQGVVFPSTHTILSQWAPPKERATLGTCAYSGNQFGTILMLATSGVI 197
            |.| .:.::..:|||.|...|..:|:.|.:.:.|.||.||          ::|.:.:|.::.|..
  Fly   139 AHI-NYVVLIVVRVVLGFMLGASWPAIHPVAAVWIPPMER----------SKFMSNMMASSLGAA 192

  Fly   198 AASPI--------GWPSIFYISGGIGCVWSVVYFFFGAGSPQECKSISAEEKKLIEMSQADEVSG 254
            ...||        ||.|:||::|.:|.:||:.:|.|...:|.....|||||::.||     |..|
  Fly   193 ITMPICGYLISVAGWASVFYLTGAVGLLWSLAWFTFVYETPATHPRISAEERREIE-----EAIG 252

  Fly   255 GQEQPKEQLPTPWLSFFTSPAFLVLIVSHSVHNWGFWTLLTEIPSYMKNILGKDIKSNALLSSLP 319
            .....|.....||.....|||...:|:.|.:..:||:|::.::|::|..||..|||.|.|.||||
  Fly   253 TTTSKKRPSHVPWGQLLCSPAVWAIIICHGLAVFGFFTVVNQLPTFMSKILHFDIKQNGLFSSLP 317

  Fly   320 YVCMFAMSFVFSSISAQLNNRNCISRSTSRKLFNSIGLWIP---MVTLVGLGYVNPDQSELAVVL 381
            |:..:.|:...|.::..|..:..:|.:.:||||.:..|.||   |:..|.|||    .:..:|.:
  Fly   318 YLGKYVMAVASSYLADYLRKKGTLSTTATRKLFTTFALVIPGLLMIVQVFLGY----DATWSVTI 378

  Fly   382 LCFTVGMNGATYLGFNTNHIDLSPNFAGILMGITNGVANIMSIIAPLIVGFIVTNEHDPEQWRIV 446
            ....:..:||...|:..|.:|::|||.|.:.|:.|.:::....::..:||.:...:.....|:||
  Fly   379 FSLALFAHGAVTAGYLGNGLDIAPNFGGTIFGLANTLSSFGGFLSTSMVGALTYKDQSFHSWQIV 443

  Fly   447 FFIAAGFYLVGNTLYVIFGKANVQPWNDPPAKPRRNSTPQVE 488
            |:|.|..|:....::.|.|...:||||:||.:.|.:...|.|
  Fly   444 FWILAATYISAAVVFAILGSGELQPWNNPPERVRISDVTQEE 485

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15096	NP_611376.1	2A0114euk	36..480	CDD:129972	148/486 (30%)
CG15096	NP_611376.1	MFS	40..464	CDD:119392	137/462 (30%)
CG3036	NP_001260058.1	2A0114euk	19..477	CDD:129972	146/480 (30%)
CG3036	NP_001260058.1	MFS	83..461	CDD:119392	122/400 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	116	1.000	Domainoid score	I288
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I245
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	1	1.000	-	-		mtm14983
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
	9	8.970